scholarly journals Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yifan Wang ◽  
Jingyi Liu ◽  
Xuhua Ying ◽  
Pengnian Charles Lin ◽  
Binhua P. Zhou
2013 ◽  
Vol 15 (2) ◽  
Author(s):  
Sahra Borges ◽  
Heike Döppler ◽  
Edith A Perez ◽  
Cathy A Andorfer ◽  
Zhifu Sun ◽  
...  

2013 ◽  
Author(s):  
Allal Ouhtit ◽  
Samineh Madani ◽  
Ishita Gupta ◽  
Somya Shanmuganathan ◽  
Hamad Al-Riyami ◽  
...  

Surgery ◽  
1997 ◽  
Vol 122 (2) ◽  
pp. 493-500 ◽  
Author(s):  
Daniel Albo ◽  
David H Berger ◽  
Thomas N Wang ◽  
Xiaolong Hu ◽  
Vicki Rothman ◽  
...  

2012 ◽  
Vol 91 (11-12) ◽  
pp. 950-960 ◽  
Author(s):  
Antonio Castro-Castro ◽  
Carsten Janke ◽  
Guillaume Montagnac ◽  
Perrine Paul-Gilloteaux ◽  
Philippe Chavrier

2011 ◽  
Vol 130 (3) ◽  
pp. 555-566 ◽  
Author(s):  
Nicole Kusuma ◽  
Delphine Denoyer ◽  
Johannes A. Eble ◽  
Richard P. Redvers ◽  
Belinda S. Parker ◽  
...  

2020 ◽  
Author(s):  
Xiaoning Yang ◽  
Junfeng Ma ◽  
Fanghua Gong ◽  
Yu Liu

Abstract Background Lung cancer is one of the most common causes of cancer-related deaths in the world, and non-small cell lung cancer (NSCLC) accounts for 85% of it. Studies have reported that microRNA-484 (miR-484) plays an important regulatory role in carcinogenesis and cancer development. Methods 25 clinical NSCLC samples were collected for microRNA array. The funvtion of miR-484 was investigated through Transwell and Mitgration assays. The expression levers of epithelial-mesenchymal transition (EMT) related factors were assessed by Western blot. Results miR-484 was up-regulated in tissues from NSCLC patients relative to tumor-adjacent normal tissues. Knocking-down miR-484 expression in A549 cells significantly suppressed tumor cell invasion and migration, suppressed epithelial-mesenchymal transition (EMT) process by increasing the expression of E-cadherin, and decreasing the expression of N-cadherin, vimentin, and MMP2. Upregulation of miR-484 expression in BEAS-2B normal lung epithelial cells significantly promoted tumor cell invasion and migration, decreased E-cadherin expression levels, and increased N-cadherin, vimentin, and MMP2 expression levels Conclusion miR-484 can promote tumor cell invasion and migration in NSCLC and may be a new target for NSCLC treatment.


Biochimie ◽  
2013 ◽  
Vol 95 (7) ◽  
pp. 1371-1378 ◽  
Author(s):  
Kelli Cristina Micocci ◽  
Ana Carolina Baptista Moreno Martin ◽  
Cyntia de Freitas Montenegro ◽  
Araceli Cristina Durante ◽  
Normand Pouliot ◽  
...  

2019 ◽  
Vol 11 (3) ◽  
pp. 109-117 ◽  
Author(s):  
Young Joon Suh ◽  
Matthew S Hall ◽  
Yu Ling Huang ◽  
So Youn Moon ◽  
Wei Song ◽  
...  

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