scholarly journals Recombinant soluble gp130 protein reduces DEN-induced primary hepatocellular carcinoma in mice

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jing Hong ◽  
Hang Wang ◽  
Guoying Shen ◽  
Da Lin ◽  
Yanxue Lin ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Primary Hepatocellular Carcinoma ◽  
Soluble Gp130

Diagnostic Value of Serum Ferritin in Primary Hepatocellular Carcinoma

Digestion ◽  
1984 ◽  
Vol 30 (4) ◽  
pp. 236-241 ◽  
Author(s):  
E. Giannoulis ◽  
C. Arvanitakis ◽  
A. Nikopoulos ◽  
I. Doutsos ◽  
A. Tourkantonis
Keyword(s):  
Hepatocellular Carcinoma ◽  
Serum Ferritin ◽  
Diagnostic Value ◽  
Primary Hepatocellular Carcinoma

scholarly journals Effect of timing of surgical resection of primary hepatocellular carcinoma on survival outcomes in elderly patients and prediction of clinical models

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yongfei He ◽  
Tianyi Liang ◽  
Shutian Mo ◽  
Zijun Chen ◽  
Shuqi Zhao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Overall Survival ◽  
Liver Cancer ◽  
Elderly Patients ◽  
Surgical Resection ◽  
Influencing Factors ◽  
The Elderly ◽  
Primary Hepatocellular Carcinoma ◽  
Surgical Timing ◽  
Duration Of Surgery

Abstract Background The effect of time delay from diagnosis to surgery on the prognosis of elderly patients with liver cancer is not well known. We investigated the effect of surgical timing on the prognosis of elderly hepatocellular carcinoma patients undergoing surgical resection and constructed a Nomogram model to predict the overall survival of patients. Methods A retrospective analysis was performed on elderly patients with primary liver cancer after hepatectomy from 2012 to 2018. The effect of surgical timing on the prognosis of elderly patients with liver cancer was analyzed using the cut-off times of 18 days, 30 days, and 60 days. Cox was used to analyze the independent influencing factors of overall survival in patients, and a prognostic model was constructed. Results A total of 232 elderly hepatocellular carcinoma patients who underwent hepatectomy were enrolled in this study. The cut-off times of 18, 30, and 60 days were used. The duration of surgery had no significant effect on overall survival. Body Mass Index, Child-Pugh classification, Tumor size Max, and Length of stay were independent influencing factors for overall survival in the elderly Liver cancer patients after surgery. These factors combined with Liver cirrhosis and Venous tumor emboli were incorporated into a Nomogram. The nomogram was validated using the clinical data of the study patients, and exhibited better prediction for 1-year, 3-year, and 5-year overall survival. Conclusions We demonstrated that the operative time has no significant effect on delayed operation in the elderly patients with hepatocellular carcinoma, and a moderate delay may benefit some patients. The constructed Nomogram model is a good predictor of overall survival in elderly patients with hepatectomy.

scholarly journals Changes in Hepatic Hemodynamics due to Primary Liver Tumours

HPB Surgery ◽  
1996 ◽  
Vol 9 (4) ◽  
pp. 245-248 ◽  
Author(s):  
F. Jakab ◽  
Z. Ráth ◽  
F. Schmal ◽  
P. Nagy ◽  
J. Faller
Keyword(s):  
Hepatocellular Carcinoma ◽  
Blood Flow ◽  
Hepatic Artery ◽  
Hepatic Blood Flow ◽  
Primary Hepatocellular Carcinoma ◽  
Portal Venous Flow ◽  
Venous Flow ◽  
Control Value ◽  
Early Results ◽  
Total Hepatic Blood Flow

Data regarding the afferent circulation of the liver in patients with primary hepatocellular carcinoma are controversial, we have carried out measurement of hepatic arterial and portal venous flow intraoperatively by transit time ultrasonic volume flowmetry. In patients with primary hepatocellular carcinoma the hepatic artery flow increased to 0.55±0.211 compared with the control value of 0.37±0.102 1/min. (p<0.01). The portal venous flow decreased from 0.61±0.212 l/min, to 0.47±l/min. p<0.01). Due to the opposite changes in the afferent circulation the total hepatic blood flow did not change significantly, compared with controls.The ratio of hepatic arterial flow to portal vein flow increased to 1.239±0.246 in patients with hepatocellular carcinoma, which is double of the control value (0.66±0.259 l/min). After resection this ratio did not change.The resection did not alter hepatic artery or portal venous flow significantly, although the total hepatic blood flow decreased significantly (p<0.01).On the basis of our early results it is possible that the ratio of the two circulations may be to deel measured with doppler ultrasound and provide diagnostic information.

Mass screening of primary hepatocellular carcinoma by alpha-fetoprotein in a rural area of Taiwan - a dried blood spot method

2008 ◽  
Vol 8 (2) ◽  
pp. 100-104 ◽  
Author(s):  
Jaw-Ching Wu ◽  
Shou-Dong Lee ◽  
Kwang-Jen Hsiao ◽  
Sun-Sang Wang ◽  
Pesus Chou ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Rural Area ◽  
Mass Screening ◽  
Alpha Fetoprotein ◽  
Primary Hepatocellular Carcinoma ◽  
Dried Blood Spot ◽  
Blood Spot
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