scholarly journals Morphology controlling method for amorphous silica nanoparticles and jellyfish-like nanowires and their luminescence properties

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Haitao Liu ◽  
Zhaohui Huang ◽  
Juntong Huang ◽  
Song Xu ◽  
Minghao Fang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Luminescence Properties

scholarly journals Insights on toxicity, safe handling and disposal of silica aerogels and amorphous nanoparticles

2021 ◽  
Author(s):  
João P. Vareda ◽  
Carlos A. García-González ◽  
Artur J. M. Valente ◽  
Rosana Simón-Vázquez ◽  
Marina Stipetic ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Silica Aerogels ◽  
Safe Handling ◽  
Synthetic Amorphous Silica ◽  
Amorphous Nanoparticles

The toxicity and ecotoxicity effects, handling and disposal of synthetic amorphous silica nanoparticles and aerogels are reviewed and discussed.

Cellular internalization and stress response of ingested amorphous silica nanoparticles in the midgut of Drosophila melanogaster

2013 ◽  
Vol 1830 (1) ◽  
pp. 2256-2266 ◽  
Author(s):  
Ashutosh Pandey ◽  
Swati Chandra ◽  
Lalit Kumar Singh Chauhan ◽  
Gopeshwar Narayan ◽  
Debapratim Kar Chowdhuri
Keyword(s):  
Drosophila Melanogaster ◽  
Stress Response ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Cellular Internalization

scholarly journals Combined Action of Human Commensal Bacteria and Amorphous Silica Nanoparticles on the Viability and Immune Responses of Dendritic Cells

2017 ◽  
Vol 24 (10) ◽  
Author(s):  
Giulia Malachin ◽  
Elisa Lubian ◽  
Fabrizio Mancin ◽  
Emanuele Papini ◽  
Regina Tavano
Keyword(s):  
Dendritic Cells ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Pathogenic Bacteria ◽  
Bacterial Species ◽  
Commensal Bacteria ◽  
Content Type ◽  
E Coli ◽  
Synergistic Induction ◽  
Ifn Γ

ABSTRACT Dendritic cells (DCs) regulate the host-microbe balance in the gut and skin, tissues likely exposed to nanoparticles (NPs) present in drugs, food, and cosmetics. We analyzed the viability and the activation of DCs incubated with extracellular media (EMs) obtained from cultures of commensal bacteria (Escherichia coli, Staphylococcus epidermidis) or pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus aureus) in the presence of amorphous silica nanoparticles (SiO2 NPs). EMs and NPs synergistically increased the levels of cytotoxicity and cytokine production, with different nanoparticle dose-response characteristics being found, depending on the bacterial species. E. coli and S. epidermidis EMs plus NPs at nontoxic doses stimulated the secretion of interleukin-1β (IL-1β), IL-12, IL-10, and IL-6, while E. coli and S. epidermidis EMs plus NPs at toxic doses stimulated the secretion of gamma interferon (IFN-γ), tumor necrosis factor alpha (TNF-α), IL-4, and IL-5. On the contrary, S. aureus and P. aeruginosa EMs induced cytokines only when they were combined with NPs at toxic concentrations. The induction of maturation markers (CD86, CD80, CD83, intercellular adhesion molecule 1, and major histocompatibility complex class II) by commensal bacteria but not by pathogenic ones was improved in the presence of noncytotoxic SiO2 NP doses. DCs consistently supported the proliferation and differentiation of CD4+ and CD8+ T cells secreting IFN-γ and IL-17A. The synergistic induction of CD86 was due to nonprotein molecules present in the EMs from all bacteria tested. At variance with this finding, the synergistic induction of IL-1β was prevalently mediated by proteins in the case of E. coli EMs and by nonproteins in the case of S. epidermidis EMs. A bacterial costimulus did not act on DCs after adsorption on SiO2 NPs but rather acted as an independent agonist. The inflammatory and immune actions of DCs stimulated by commensal bacterial agonists might be altered by the simultaneous exposure to engineered or environmental NPs.

Emerging investigator series: Long-term exposure of amorphous silica nanoparticles disrupts the lysosomal and cholesterol homeostasis in macrophages

2021 ◽  
Author(s):  
Ronglin Ma ◽  
Xiaoming Cai ◽  
Ye Zhou ◽  
Xi Liu ◽  
Di Wu ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Cholesterol Homeostasis

Amorphous silica nanoparticles (ASiNPs) are generally considered to be biocompatible with limited acute toxicity. These nanoparticles were therefore exploited in diverse nanoproducts (e.g. foods and cosmetics) and may be released...

Microarray-assisted size-effect study of amorphous silica nanoparticles on human bronchial epithelial cells

Nanoscale ◽  
2019 ◽  
Vol 11 (47) ◽  
pp. 22907-22923 ◽  
Author(s):  
Yang Li ◽  
Junchao Duan ◽  
Xiangyuan Chai ◽  
Man Yang ◽  
Ji Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Epithelial Cells ◽  
Size Effect ◽  
Toxic Effect ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Effect Study ◽  
Human Bronchial Epithelial Cells ◽  
Bronchial Epithelial ◽  
Size Dependent

Silica nanoparticles produced size-dependent toxic effect on the gene expression profile of BEAS-2B cells.

scholarly journals Genotoxicity of amorphous silica nanoparticles: Status and prospects

2019 ◽  
Vol 16 ◽  
pp. 106-125 ◽  
Author(s):  
Mostafa Yazdimamaghani ◽  
Philip J. Moos ◽  
Marina A. Dobrovolskaia ◽  
Hamidreza Ghandehari
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

2020 ◽  
Vol 5 (12) ◽  
pp. 886-909 ◽  
Author(s):  
Jonas G. Croissant ◽  
Kimberly S. Butler ◽  
Jeffrey I. Zink ◽  
C. Jeffrey Brinker
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Environmental Implications ◽  
Synthetic Amorphous Silica ◽  
Nanoparticles Toxicity

A facile method to study the bioaccumulation kinetics of amorphous silica nanoparticles by quantum dot embedding

2018 ◽  
Vol 5 (12) ◽  
pp. 2830-2841
Author(s):  
Xiao-Mei Zang ◽  
Jia-Ming Li ◽  
Ying Wang ◽  
Yue-Yue Liu ◽  
Zhong-Bo Wei ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Kinetics Of

A facile method was developed to study the bioaccumulation kinetics of amorphous silica nanoparticles (AmSiNPs) by embedding the particles with quantum dots (QDs) and then using Cd as the tracer.

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