scholarly journals Preventive obesity agent montmorillonite adsorbs dietary lipids and enhances lipid excretion from the digestive tract

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Pengfei Xu ◽  
Shu Dai ◽  
Jing Wang ◽  
Jun Zhang ◽  
Jin Liu ◽  
...  
Author(s):  
T. Caceci ◽  
G. B. Chapman

The deleterious effects of agricultural insecticides on non-target organisms have been under investigation for a number of years. Most studies have dealt with the degree of toxicity, mechanism of action, metabolism, or distribution in the biosphere. There has been comparatively little interest in morphological effects of an insecticide at its site of entry. Toxaphene, a general-purpose organochlorine insecticide that is widely and heavily applied in the U.S. is quite toxic to fish. It can be absorbed via the gills or the gut. This study examined the effects of Toxaphene on the absorptive cells of the anterior intestinal bulb in goldfish (Carassius auratus). These cells are involved in the uptake of dietary lipids; since Toxaphene is lipid-soluble, this was considered the likeliest region of the digestive tract to exhibit damage due to its presence.


2012 ◽  
Vol 82 (2) ◽  
pp. 85-93 ◽  
Author(s):  
Y. Kim ◽  
H. Shin ◽  
S. Lee

In the present study, the nutritional quality of four grains including adlay (AD), buckwheat (BW), glutinous barley (GB), and white rice (WR) were evaluated in terms of plasma lipid parameters, gut transit time, and thickness of the aortic wall in rats. The rats were then raised for 4 weeks on the high-fat diet based on the American Institute of Nutrition-93 (AIN-93 G) diets containing 1 % cholesterol and 20 % dietary lipids. Forty male rats were divided into 4 groups and raised for 4 weeks with a diet containing one of the following grains: WR, AD, BW, or WB. The level of thiobarbituric acid-reactive substances (TBARS) in liver was shown to be higher in rats by the order of those fed WR, AD, GB, and BW. This indicates that other grains decreased oxidative stress in vivo more than WR. The superoxide dismutase, glutathione, glutathione peroxidase, and glutathione reductase levels in the AD, BW, and GB groups were significantly higher than those in the WR group (p < 0.05). Plasma lipid profiles differed significantly according to grain combination, and decreased aortic wall thickness was consistent with the finding of decreased plasma low-density lipoprotein cholesterol (LDL-C) (p < 0.05) and increased high-density lipoprotein (HDL-C) in rats fed AD, BW, and GB (p < 0.001). The antioxidant and hypolipidemic capacities of grains are quite high, especially those of adlay, buckwheat, and glutinous barley. In conclusion, this study has demonstrated that the whole grains had a cardioprotective effect. This effect was related to several mechanisms that corresponded to lowering plasma lipids, decreasing TBARS, and increasing antioxidant activities.


2018 ◽  
Author(s):  
F Junquera ◽  
E Brullet ◽  
E Martínez-Bauer ◽  
V Puig-Diví ◽  
M Miquel ◽  
...  
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