scholarly journals Association between the DOCK7, PCSK9 and GALNT2 Gene Polymorphisms and Serum Lipid levels

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Tao Guo ◽  
Rui-Xing Yin ◽  
Feng Huang ◽  
Li-Mei Yao ◽  
Wei-Xiong Lin ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels

Apolipoprotein B gene polymorphisms: Prevalence and impact on serum lipid levels in hypercholesterolemic individuals from Brazil

2000 ◽  
Vol 151 (1) ◽  
pp. 264-265
Author(s):  
S.A. Cavalli ◽  
L.A. Salazar ◽  
M.H. Hirata ◽  
N. Forti ◽  
J. Diament ◽  
...  
Keyword(s):  
Apolipoprotein B ◽  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Apolipoprotein B Gene

scholarly journals Interactions of the Apolipoprotein A5 Gene Polymorphisms and Alcohol Consumption on Serum Lipid Levels

PLoS ONE ◽  
2011 ◽  
Vol 6 (3) ◽  
pp. e17954 ◽  
Author(s):  
Rui-Xing Yin ◽  
Yi-Yang Li ◽  
Wan-Ying Liu ◽  
Lin Zhang ◽  
Jin-Zhen Wu
Keyword(s):  
Alcohol Consumption ◽  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Apolipoprotein A5 ◽  
Serum Lipid Levels

scholarly journals ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses

2011 ◽  
Vol 10 (1) ◽  
pp. 56 ◽  
Author(s):  
Vana Kolovou ◽  
Genovefa Kolovou ◽  
Apostolia Marvaki ◽  
Agathi Karakosta ◽  
Georgios Vasilopoulos ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Atp Binding ◽  
Lipid Levels ◽  
Atp Binding Cassette Transporter ◽  
Serum Lipid Levels ◽  
Atp Binding Cassette

Association of apolipoprotein A5 gene polymorphisms and serum lipid levels

2011 ◽  
Vol 21 (12) ◽  
pp. 947-956 ◽  
Author(s):  
Y.-Y. Li ◽  
R.-X. Yin ◽  
C.-Q. Lai ◽  
M. Li ◽  
X.-J. Long ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Apolipoprotein A5 ◽  
Serum Lipid Levels

scholarly journals Association between CYP2C19 gene polymorphisms and lipid metabolism in Chinese patients with ischemic stroke

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052093465
Author(s):  
Yunxue Bai ◽  
Ruicheng Huang ◽  
Lagen Wan ◽  
Rui Zhao
Keyword(s):  
Ischemic Stroke ◽  
Lipid Metabolism ◽  
Gene Polymorphisms ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Cyp2c19 Gene

Objective The CYP2C19 genetic variation may be involved in the development of atherosclerotic cardiovascular disease (ASCVD). Serum lipid levels are important risk factors for ASCVD, but the effect of the CYP2C19 gene on serum lipid metabolism remains unclear. This retrospective cohort study investigated the relationship between the CYP2C19 gene polymorphism and serum lipid levels in patients with ischemic stroke (IS). Methods IS patients (n = 230) and control subjects (n = 100) were enrolled. All patients were diagnosed with IS via clinical manifestations and brain magnetic resonance imaging. All patients were genotyped. Results Triglyceride (TG), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-c), and apolipoprotein B (ApoB) levels were significantly higher and high-density lipoprotein-cholesterol (HDL-c) and apolipoprotein A1 (ApoA1) levels were significantly lower in the IS group compared with the control group. Lower ApoA1 levels and higher ApoB levels were significant predictive factors for IS. Patients with higher ApoB levels had a higher risk of IS recurrence. Compared with extensive metabolizers, intermediate and poor CYP2C19 metabolizers had a higher risk of IS recurrence. Conclusions Our study indicates CYP2C19 gene polymorphisms are related to lipid metabolism in patients with IS. IS patients who are poor CYP2C19 metabolizers may have a higher risk of disease recurrence.

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