scholarly journals Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Yezheng Tao ◽  
Li Ma ◽  
Zhaohui Liao ◽  
Qiumin Le ◽  
Jialing Yu ◽  
...  
Keyword(s):  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Nuclear Signaling ◽  
Adult Hippocampus

scholarly journals The orphan nuclear receptor TLX: an emerging master regulator of cross-talk between microglia and neural precursor cells

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Paul J. Lucassen ◽  
Anne-Marie van Dam ◽  
Prasanna Kandel ◽  
Pascal Bielefeld ◽  
Aniko Korosi ◽  
...  
Keyword(s):  
Nuclear Receptor ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Orphan Nuclear Receptor ◽  
Health And Disease ◽  
Adult Hippocampus ◽  
Intensive Investigation ◽  
The Many ◽  
The Brain

Abstract Neuroinflammation and neurogenesis have both been the subject of intensive investigation over the past 20 years. The sheer complexity of their regulation and their ubiquity in various states of health and disease have sometimes obscured the progress that has been made in unraveling their mechanisms and regulation. A recent study by Kozareva et al. (Neuronal Signaling (2019) 3), provides evidence that the orphan nuclear receptor TLX is central to communication between microglia and neural precursor cells and could help us understand how inflammation, mediated by microglia, influences the development of new neurons in the adult hippocampus. Here, we put recent studies on TLX into the context of what is known about adult neurogenesis and microglial activation in the brain, along with the many hints that these processes must be inter-related.

Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus

2009 ◽  
Vol 23 (9) ◽  
pp. 3121-3128 ◽  
Author(s):  
Susanne A. Wolf ◽  
Barbara Steiner ◽  
Antje Wengner ◽  
Martin Lipp ◽  
Thomas Kammertoens ◽  
...  
Keyword(s):  
Immune Response ◽  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Neural Precursor ◽  
Peripheral Immune Response ◽  
Adult Hippocampus

scholarly journals c-jun is differentially expressed in embryonic and adult neural precursor cells

2017 ◽  
Vol 147 (6) ◽  
pp. 721-731 ◽  
Author(s):  
Fumiaki Kawashima ◽  
Kengo Saito ◽  
Hirofumi Kurata ◽  
Yoshihiro Maegaki ◽  
Tetsuji Mori
Keyword(s):  
Precursor Cells ◽  
Neural Precursor Cells ◽  
Differentially Expressed ◽  
Neural Precursor
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