scholarly journals Klotho-related Molecules Upregulated by Smoking Habit in Apparently Healthy Men: A Cross-sectional Study

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Kaori Nakanishi ◽  
Makoto Nishida ◽  
Masaya Harada ◽  
Tohru Ohama ◽  
Noritaka Kawada ◽  
...  
Keyword(s):  
Smoking Habit ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Healthy Men ◽  
Apparently Healthy

scholarly journals Associations between dietary patterns and gene expression profiles of healthy men and women: a cross-sectional study

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Annie Bouchard-Mercier ◽  
Ann-Marie Paradis ◽  
Iwona Rudkowska ◽  
Simone Lemieux ◽  
Patrick Couture ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dietary Patterns ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Men And Women ◽  
Healthy Men

scholarly journals Tobacco Use among Adolescents of a Public School of Kaski District

2020 ◽  
Vol 10 (1) ◽  
pp. 59-63
Author(s):  
Sailaja Sharma ◽  
Ratna Shila Banstola ◽  
Sakuntala Pageni
Keyword(s):  
Public School ◽  
Tobacco Use ◽  
Smoking Habit ◽  
Peer Pressure ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Family Influence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Self Administered Questionnaire

Introduction: Tobacco is one of the proven risk factors, contributes substantially to the rising epidemic of non-communicable diseases. Methods: This cross-sectional study was conducted to determine the prevalence of tobacco use and associated factors among adolescents of a selected public School in Kaski district. Non-probability purposive sampling technique was adopted and data was collected with self-administered questionnaire from 168 respondents. Results: The prevalence of tobacco-use was 19.6 percent and mean age of initiation was13.84 years. The most common reasons for smoking were peer pressure (63.3%), imitation (27.3%), family influence (27.3%) and quest for new experience (21.2%). Tobacco-use was strongly associated with ethnicity (p=0.03), mother's education level (p=0.02), father's occupation (p=0.03), peer pressure (p=0.01) and friends smoking habit (p=0.03). Conclusion: Tobacco-focused interventions are required for school going adolescents to promote cessation among users and prevent its initiation.

scholarly journals Dysfunctional Adiposity Index as a Useful Clinical Tool for Early Identification of Adipose Tissue Morpho-Functional Abnormalities and Cardiometabolic Disorders in Apparently Healthy Subjects

2020 ◽  
Author(s):  
Juan Reyes-Barrera ◽  
Victor H. Sainz-Escárrega ◽  
Aida X. Medina-Urritia ◽  
Esteban Jorge-Galarza ◽  
Horacio Osorio-Alonso ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adipose Tissue ◽  
Clinical Practice ◽  
Early Identification ◽  
Healthy Subjects ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adiposity Index ◽  
Apparently Healthy

Abstract BackgroundCompared to body mass index (BMI), waist circumference (WC), and adiposity measurements, adipose tissue morpho-functionality evaluations are more consistent predictors of cardiometabolic abnormalities. However, these evaluations require determination of adipokines and other non-routine biochemical parameters, which is not feasible in clinical practice. The present study establishes dysfunctional adiposity index (DAI) as a simple, accessible, and reliable marker of early adipocytes morpho-functional abnormalities and cardiometabolic diseases.MethodsTo establish the DAI constant parameters, 340 subjects (134 males and 206 females) without cardiovascular risk factors were selected from a cross-sectional study. Then, DAI was calculated in 36 healthy subjects who underwent subcutaneous adipose tissue biopsy, for whom adipocytes number and size, body composition, circulating adipokines, glucose, insulin, and lipids were also determined. The correlation of DAI with adipocyte morphology (size/number of adipocytes) and functionality (adiponectin/leptin ratio) was analyzed. The receiver operating characteristic curve was used to define the optimal DAI cut-off point to identify metabolic abnormalities. Finally, the independent association of DAI with cardiometabolic abnormalities was determined in 1418 subjects from the cross-sectional study through multivariate analyses.ResultsThe constant parameters to calculate the DAI were [WC/[22.79+[2.68*BMI]]]*[triglycerides (TG, mmol/L)/1.37]*[1.19/high density lipoprotein-cholesterol (HDL-C, mmol/L)] for males, and [WC/[24.02+[2.37*BMI]]]*[TG(mmol/L)/1.32]*[1.43/HDL-C(mmol/L)] for females. In subjects underwent biopsy, DAI correlated with adipocytes mean area (r=0.358; p=0.032), adipocyte number (r=-0.381; p=0.024), adiponectin/leptin ratio (r=-0.483; p=0.003), and systemic inflammation markers. Compared to BMI, WC, and visceral fat, DAI was the only determination associated with insulin resistance (area under the curve: 0.743; p = 0.017). In the cross-sectional study, DAI ≥1.065 was independently associated with diabetes (OR: 1.96; 95%CI: 1.36-2.84), non-alcoholic fatty liver disease (OR: 2.57; 95%CI: 1.98-3.33), subclinical atherosclerosis (OR: 1.74; 95%CI: 1.02-2.94), and hypertension (OR: 1.44; 95%CI: 1.10-1.88).ConclusionsThe present study establishes the constant parameters to calculate the DAI and highlights that a DAI ≥ 1.065 is associated with early cardiometabolic abnormalities independently of adiposity and other risk factors. Since DAI is calculated using accessible parameters routinely used in the clinic, this indicator can be easily incorporated in clinical practice for the early identification of adipose tissue abnormalities in apparently healthy subjects.

scholarly journals Cigarette smoking and metabolic syndrome components: a cross-sectional study from Maracaibo City, Venezuela

F1000Research ◽  
2019 ◽  
Vol 7 ◽  
pp. 565 ◽  
Author(s):  
Valmore Bermudez ◽  
Luis Carlos Olivar ◽  
Wheeler Torres ◽  
Carla Navarro ◽  
Robys Gonzalez ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cigarette Smoking ◽  
Smoking Habit ◽  
Cross Sectional Study ◽  
Abdominal Circumference ◽  
Related Factor ◽  
Sectional Study ◽  
Cross Sectional ◽  
Former Smokers ◽  
Metabolic Syndrome Components

Background: A growing body of evidence suggests that cigarette smoking can cause the onset of metabolic syndrome prior to cardiovascular diseases. Therefore, the objective of this study was to evaluate the relationship between smoking habit and metabolic syndrome components in an adult population from Maracaibo city, Venezuela. Methods: The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study with random and multi-stage sampling. In this sub-study, 2212 adults from both genders were selected. On the basis of their medical background, they were classified as smokers, non-smokers and former smokers. Metabolic syndrome was defined according to Harmonizing 2009 criteria, using population-specific abdominal circumference cut-off points. The association between risk factors was evaluated using a logistic regression model. Results: In the studied population, 14.8% were smokers, 15.4% were former smokers. In the multivariate analysis, the presence of metabolic syndrome (smokers: OR, 1.54; 95% CI, 1.11–2.14; p=0.010) and its components were related to cigarette smoking, with the exception of hyperglycemia. High blood pressure was inversely associated with current smoking status (smokers: OR, 0.70 (0.51–0.95); p=0.025). Conclusion: Cigarette smoking represents a related factor with metabolic syndrome, being associated with low high-density lipoprotein-cholesterol, increased abdominal circumference and elevated triacylglyceride levels. Former smokers did not present a greater risk for developing this metabolic disease when compared to non-smokers. The effect of avoiding this habit should be evaluated in future studies in our population.

scholarly journals Community based hematological reference intervals among apparently healthy adolescents aged 12-17 years in Mekelle city, Tigrai, northern Ethiopia: A cross sectional study

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0234106
Author(s):  
Hagos Haileslasie ◽  
Aster Tsegaye ◽  
Gebreyohanes Teklehaymanot ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Reference Intervals ◽  
Northern Ethiopia ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Mekelle City ◽  
Apparently Healthy

Associations between white blood cells count and obesity in apparently healthy young adults

2020 ◽  
Vol 50 (6) ◽  
pp. 1013-1019
Author(s):  
Fatemeh Ghannadiasl
Keyword(s):  
Young Adults ◽  
Cardiovascular Diseases ◽  
Blood Cells ◽  
White Blood Cells ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Content Type ◽  
Apparently Healthy

Purpose The elevated white blood cells (WBCs) count has been reported to be a predictor of cardiovascular diseases, diabetes, hypertension and metabolic syndrome. This study aims to determine the associations between WBCs count and obesity in apparently healthy young adults. Design/methodology/approach In this cross-sectional study, the authors evaluated the body mass index (BMI) in 392 apparently healthy young adults of both sexes. The WBCs count was measured using standard counter techniques. The inclusion criteria were the agreement to participate in the study, between 18 and 25 years of age, lack of self-reported diseases such as cardiovascular diseases, hypertension, kidney and infectious diseases. Findings According to the BMI classification, underweight and overweight or obesity were observed in 14.58 and 11.48 per cent of young adults, respectively. The mean WBC was 6.5 ± 1.5 (×10³ cells/µL). Higher values of WBCs were found in women than in men (p = 0.02). The young adults with higher BMI had a higher WBCs count. There was a positive correlation between WBCs count and weight and BMI (r = 0.19 and r = 0.22, p < 0.001, respectively). Research limitations/implications This research was a cross-sectional study. Future studies are suggested using longitudinal studies to examine more relationships between obesity and WBCs count in apparently healthy young adults. Practical implications The results of this study provide evidence for weight management in this age group to reduce diseases associated with increased WBCs count. Originality/value The WBCs count was related to increasing levels of BMI per cent 2 C even in the normal range.

Sign in / Sign up

Export Citation Format

Share Document