scholarly journals Variants in the Regulatory Region of WNT5A Reduced Risk of Cardiac Conotruncal Malformations in the Chinese Population

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Peiqiang Li ◽  
Haijie Li ◽  
Yufang Zheng ◽  
Bin Qiao ◽  
Wenyuan Duan ◽  
...  
Keyword(s):  
Chinese Population ◽  
Regulatory Region ◽  
Conotruncal Malformations ◽  
Reduced Risk

scholarly journals The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population

Oncotarget ◽  
2016 ◽  
Vol 7 (22) ◽  
pp. 31972-31979 ◽  
Author(s):  
Xiaotian Yuan ◽  
Yan Meng ◽  
Ping Li ◽  
Nan Ge ◽  
Feng Kong ◽  
...  
Keyword(s):  
Chinese Population ◽  
Han Chinese ◽  
Han Chinese Population ◽  
Upper Tract ◽  
Urothelial Carcinomas ◽  
Reduced Risk

Relationship Between Time of Day Physical Exercise and the Reduced Risk of Coronary Artery Disease in a Chinese Population

2014 ◽  
Vol 24 (2) ◽  
pp. 139-147 ◽  
Author(s):  
Huan Zhao ◽  
Xiao-Qiu Chu ◽  
Xiao-Qing Lian ◽  
Ze-Mu Wang ◽  
Wei Gao ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Physical Exercise ◽  
Chinese Population ◽  
Time Of Day ◽  
Protective Effects ◽  
Time Activity ◽  
Artery Disease ◽  
Reduced Risk

Purpose:Exercise leads to a lower risk of coronary artery disease (CAD). However, whether time of day physical exercise has effects on CAD is still unclear. The present study is to investigate the relationship between time of day physical exercise and angiography determined CAD in a Chinese population.Subjects:A total of 1,129 consecutive participants who underwent coronary angiography for the first time were enrolled in our study. Participants were divided into non-CAD group and CAD group according to the result of coronary angiography. We used a predesigned questionnaire—the work-related activity, leisure-time activity, and physical exercise information were recorded in the form of self-reporting.Results:Doing physical exercise was associated with a reduced risk of CAD, after adjusting the established and potential confounders, with an adjusted odds ratio (OR) of 0.48 (95% CI, 0.35–0.67) compared with those who did not any physical exercise. Moreover, the risk of CAD could linearly decrease with increase of intensity, duration and frequency of exercise. Further stratification analysis revealed that the protective effects of exercise were more significant in the afternoon and evening group than in the morning and forenoon group. The adjusted ORs of doing physical exercise in morning, forenoon, afternoon, and evening groups were 0.53 (0.36–0.78), 0.51(0.27–0.96), 0.46(0.25–0.85), 0.43(0.28–0.66), respectively, compared with nonexerciser (p < .05).Conclusions:Doing physical exercise can decrease the risk of CAD, and exercising in the afternoon or evening may have more significant effects on the prevention of CAD than in other time of day.

rs11098403 polymorphism near NDST3 is associated with a reduced risk of schizophrenia in a Han Chinese population

2014 ◽  
Vol 581 ◽  
pp. 42-45 ◽  
Author(s):  
Li-Ze Gu ◽  
Teng Jiang ◽  
Zao-Huo Cheng ◽  
Yue-Chun Zhang ◽  
Meng-Meng Ou ◽  
...  
Keyword(s):  
Chinese Population ◽  
Han Chinese ◽  
Han Chinese Population ◽  
Reduced Risk

scholarly journals Dinucleotide polymorphism ofp73 gene is associated with a reduced risk of lung cancer in a Chinese population

2005 ◽  
Vol 114 (3) ◽  
pp. 455-460 ◽  
Author(s):  
Zhibin Hu ◽  
Xiaoping Miao ◽  
Hongxia Ma ◽  
Wen Tan ◽  
Xinru Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Chinese Population ◽  
Reduced Risk

scholarly journals Effects of sleep habits on acute myocardial infarction risk and severity of coronary artery disease in Chinese population

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoqing Lian ◽  
Jie Gu ◽  
Sibo Wang ◽  
Jianjun Yan ◽  
Xiaowen Chen ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Sleep Duration ◽  
Chinese Population ◽  
Gensini Score ◽  
Sleep Habits ◽  
Short Sleep Duration ◽  
Short Sleep ◽  
Increased Risk ◽  
Artery Disease ◽  
Reduced Risk

Abstract Background Growing evidence indicates that poor sleep harms health. Early to bed and early to rise is considered as a healthy lifestyle in Chinese population. The current study aimed to examine the effects of sleep habits on acute myocardial infarction (AMI) risk and severity of coronary artery disease (CAD) in Chinese population from two centers. Methods A total of 873 patients including 314 AMI cases and 559 controls were recruited from the inpatient cardiology department of the Affiliated Jiangning Hospital and the First Affiliated Hospital of Nanjing Medical University. 559 controls included 395 CAD cases and 164 non-CAD cases. We used a 17-item sleep factors questionnaire (SFQ) to evaluate sleep habits comprehensively by face-to-face interview. The severity of CAD was assessed by Gensini score in AMI and CAD groups. The effects of sleep factors on AMI risk and Gensini score were examined by unconditional logistic regression. Results After mutually adjustment for other sleep factors and demographic characteristics, the timing of sleep (24:00 and after) and morning waking (after 7:00) and sleep duration (< 6 h) were associated with increased risk of AMI (OR = 4.005, P < 0.001, OR = 2.544, P = 0.011 and OR = 2.968, P < 0.001, respectively). Lower level of light exposure at night was correlated with reduced risk of AMI (OR = 0.243, P = 0.009). In subgroup analysis by age, both late sleep timing and short sleep duration were associated with increased risk of AMI regardless of age. In subjects with age ≤ 65 years, daytime napping was related to reduced risk of AMI (OR = 0.645, P = 0.046). In subjects with age > 65 years, the frequency of night-time waking (3 times) was associated with increased risk of AMI (OR = 3.467, P = 0.035). Short sleep duration was correlated with increased risk of high Gensini score (OR = 2.374, P < 0.001). Conclusion Sleep insufficiency is an important risk factor both for AMI risk and CAD severity. Late sleeping is also associated with increased risk of AMI. In young and middle-aged people, regular naps may have a protective effect. Graphic abstract

scholarly journals A polymorphism in miR-1262 regulatory region confers the risk of lung cancer in Chinese population

2017 ◽  
Vol 141 (5) ◽  
pp. 958-966 ◽  
Author(s):  
Kaipeng Xie ◽  
Mengxi Chen ◽  
Meng Zhu ◽  
Cheng Wang ◽  
Na Qin ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Chinese Population ◽  
Regulatory Region
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