scholarly journals A spontaneous depressive pattern in adult female rhesus macaques

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Dongdong Qin ◽  
Joshua Rizak ◽  
Xunxun Chu ◽  
Zhifei Li ◽  
Shangchuan Yang ◽  
...  
Keyword(s):  
Adult Female ◽  
Rhesus Macaques ◽  
Female Rhesus ◽  
Female Rhesus Macaques

scholarly journals Intermittent pair-housing, pair relationship qualities, and HPA activity in adult female rhesus macaques

2018 ◽  
Vol 80 (5) ◽  
pp. e22762
Author(s):  
Darcy L. Hannibal ◽  
Lauren C. Cassidy ◽  
Jessica Vandeleest ◽  
Stuart Semple ◽  
Allison Barnard ◽  
...  
Keyword(s):  
Adult Female ◽  
Rhesus Macaques ◽  
Relationship Qualities ◽  
Female Rhesus ◽  
Female Rhesus Macaques

Affiliation and aggression among adult female rhesus macaques: a genetic analysis of paternal cohorts

Behaviour ◽  
2002 ◽  
Vol 139 (2) ◽  
pp. 371-391 ◽  
Author(s):  
Wolf Jürgen Streich ◽  
Anja Widdig ◽  
Fred Bercovitch ◽  
Peter Nürnberg ◽  
Michael Krawczak
Keyword(s):  
Genetic Analysis ◽  
Adult Female ◽  
Rhesus Macaques ◽  
Female Rhesus ◽  
Female Rhesus Macaques

scholarly journals Heritability and relationship of oxytocin receptor gene variants with social behavior and central oxytocin in colony-reared adult female rhesus macaques

2019 ◽  
Author(s):  
Desirée De Leon ◽  
Hasse Walum ◽  
Kai M. McCormack ◽  
Jamie L. LaPrairie ◽  
Stephen G. Lindell ◽  
...  
Keyword(s):  
Social Behavior ◽  
Adult Female ◽  
Complex Traits ◽  
Statistical Power ◽  
Environmental Control ◽  
Rhesus Macaques ◽  
Receptor Gene ◽  
Human Studies ◽  
Female Rhesus ◽  
Female Rhesus Macaques

AbstractThe genetic contributions to sociality are an important research focus for understanding individual variation in social function and risk of social deficits in neurodevelopmental disorders (e.g. autism). The neuropeptide oxytocin (OXT) and its receptor, OXTR, influence social behavior across species. In humans and animals, common variants within the OXTR gene (OXTR) have been associated with varying socio-behavioral traits. However, the reported magnitude of influence of individual variants on complex behavior has been inconsistent. Compared to human studies, non-human primate (NHP) studies in controlled environments have the potential to result in robust effects detectable in relatively small samples. Here we estimate heritability of social behavior and central OXT concentrations in 214 socially-housed adult female rhesus macaques, a species sharing high similarity with humans in genetics, physiology, brain and social complexity. We present a bioinformatically-informed approach for identifying single nucleotide polymorphisms (SNPs) with likely biological relevance. We tested 13 common SNPs in regulatory and coding regions of OXTR for associations with behavior (pro-social, anxiety-like, and aggressive) and OXT concentration in cerebrospinal fluid (CSF). We found moderate rates of heritability for both social behavior and CSF OXT concentrations. No tested SNPs showed significant associations with behaviors or CSF in this sample. Associations between OXT CSF and social behavior were not significant either. SNP effect sizes were generally comparable to those reported in human studies of complex traits. While environmental control and a socio-biological similarity with humans is an advantage of rhesus models for detecting smaller genetic effects, it is insufficient to obviate large sample sizes necessary for appropriate statistical power.

Social capital and physiological stress levels in free-ranging adult female rhesus macaques

2011 ◽  
Vol 102 (1) ◽  
pp. 76-83 ◽  
Author(s):  
L.J.N. Brent ◽  
S. Semple ◽  
C. Dubuc ◽  
M. Heistermann ◽  
A. MacLarnon
Keyword(s):  
Social Capital ◽  
Adult Female ◽  
Physiological Stress ◽  
Rhesus Macaques ◽  
Female Rhesus ◽  
Stress Levels ◽  
Free Ranging ◽  
Female Rhesus Macaques

scholarly journals Paternal relatedness and age proximity regulate social relationships among adult female rhesus macaques

2001 ◽  
Vol 98 (24) ◽  
pp. 13769-13773 ◽  
Author(s):  
A. Widdig ◽  
P. Nurnberg ◽  
M. Krawczak ◽  
W. J. Streich ◽  
F. B. Bercovitch
Keyword(s):  
Social Relationships ◽  
Adult Female ◽  
Rhesus Macaques ◽  
Female Rhesus ◽  
Female Rhesus Macaques

Paternal kin bias in the agonistic interventions of adult female rhesus macaques (Macaca mulatta)

2006 ◽  
Vol 61 (2) ◽  
pp. 205-214 ◽  
Author(s):  
Anja Widdig ◽  
Wolf Jürgen Streich ◽  
Peter Nürnberg ◽  
Peter J. P. Croucher ◽  
Fred B. Bercovitch ◽  
...  
Keyword(s):  
Adult Female ◽  
Macaca Mulatta ◽  
Rhesus Macaques ◽  
Female Rhesus ◽  
Female Rhesus Macaques
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