scholarly journals An adenosine A3 receptor agonist inhibits DSS-induced colitis in mice through modulation of the NF-κB signaling pathway

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Tianhua Ren ◽  
Ting Tian ◽  
Xiao Feng ◽  
Shicai Ye ◽  
Hao Wang ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Receptor Agonist ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist

scholarly journals Erratum to: The effects of the adenosine A3 receptor agonist IB-MECA on sodium taurocholate-induced experimental acute pancreatitis

2013 ◽  
Vol 36 (9) ◽  
pp. 1167-1167
Author(s):  
Beata Prozorow-Krol ◽  
Agnieszka Korolczuk ◽  
Grazyna Czechowska ◽  
Maria Slomka ◽  
Agnieszka Madro ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Receptor Agonist ◽  
Sodium Taurocholate ◽  
Experimental Acute Pancreatitis ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist

scholarly journals The effects of the adenosine A3 receptor agonist IB-MECA on sodium taurocholate-induced experimental acute pancreatitis

2013 ◽  
Vol 36 (9) ◽  
pp. 1126-1132 ◽  
Author(s):  
Beata Prozorow-Krol ◽  
Agnieszka Korolczuk ◽  
Grazyna Czechowska ◽  
Maria Slomka ◽  
Agnieszka Madro ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Receptor Agonist ◽  
Sodium Taurocholate ◽  
Experimental Acute Pancreatitis ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist

scholarly journals IB-MECA, an Adenosine A3 Receptor Agonist, Does Not Influence Survival of Lethally γ-Irradiated Mice

2012 ◽  
pp. 649-654
Author(s):  
M. HOFER ◽  
M. POSPÍŠIL ◽  
L. DUŠEK ◽  
Z. HOFEROVÁ ◽  
D. KOMŮRKOVÁ
Keyword(s):  
Receptor Agonist ◽  
Combined Treatment ◽  
Radiation Doses ◽  
Moderate Increase ◽  
Adenosine A3 Receptor ◽  
Post Irradiation ◽  
Administration Routes ◽  
Treatment Regimens ◽  
Drug Doses ◽  
Adenosine A3 Receptor Agonist

In our previous studies, IB-MECA, an adenosine A3 receptor agonist, was found to stimulate proliferation of hematopoietic progenitor and precursor cells in mice. This property of IB-MECA was considered to be responsible for its ability to support regeneration of suppressed hematopoiesis after irradiation with sublethal doses of γ-rays when the drug was given in a post-irradiation treatment regimen. This study was aimed at assessing the ability of IB-MECA to influence a 30-day survival of lethally irradiated mice. In a series of experiments, IB-MECA was administered following various lethal radiation doses in various numbers of drug doses and various administration routes. Though in some of these experiments a moderate increase in 30-day survival was observed in IB-MECA-treated mice, the differences in comparison with the controls were not significantly different. It can be inferred from these results and those of previous studies assessing the effects of IB-MECA after sublethal radiation doses that IB-MECA can probably influence only a substantially preserved hematopoiesis like that remaining after sublethal irradiation. Future studies should be aimed at evaluation of the abilities of IB-MECA to influence post-irradiation survival when administered as a part of combined treatment regimens.

scholarly journals Neuroprotective Roles of the Adenosine A3 Receptor Agonist AST-004 in Mouse Model of Traumatic Brain Injury

2021 ◽  
Author(s):  
Eda Bozdemir ◽  
Fabio A. Vigil ◽  
Sang H. Chun ◽  
Liliana Espinoza ◽  
Vladislav Bugay ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mouse Model ◽  
Receptor Agonist ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist

Protection from myocardial stunning by ischaemia and hypoxia with the adenosine A3 receptor agonist, IB-MECA

2003 ◽  
Vol 477 (3) ◽  
pp. 235-245 ◽  
Author(s):  
Helen L Maddock ◽  
Neil M Gardner ◽  
Nassirah Khandoudi ◽  
Antoine Bril ◽  
Kenneth J Broadley
Keyword(s):  
Myocardial Stunning ◽  
Receptor Agonist ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist

scholarly journals Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats

1996 ◽  
Vol 308 (3) ◽  
pp. 311-314 ◽  
Author(s):  
Erno A. Van Schaick ◽  
Kenneth A. Jacobson ◽  
Hea O. Kim ◽  
Adriaan P. Ijzerman ◽  
Meindert Danhof
Keyword(s):  
Histamine Release ◽  
Receptor Agonist ◽  
Hemodynamic Effects ◽  
Adenosine A3 Receptor ◽  
Conscious Rats ◽  
Adenosine A3 Receptor Agonist

Adenosine A3 receptor agonist acts as a homeostatic regulator of bone marrow hematopoiesis

2007 ◽  
Vol 61 (6) ◽  
pp. 356-359 ◽  
Author(s):  
Michal Hofer ◽  
Milan Pospíšil ◽  
Vladimír Znojil ◽  
Jiřina Holá ◽  
Antonín Vacek ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Receptor Agonist ◽  
Adenosine A3 Receptor ◽  
Adenosine A3 Receptor Agonist
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