scholarly journals AhR expression and polymorphisms are associated with risk of coronary arterial disease in Chinese population

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Shian Huang ◽  
Xiaorong Shui ◽  
Yuan He ◽  
Yiqiang Xue ◽  
Jianwen Li ◽  
...  
Keyword(s):  
Chinese Population ◽  
Arterial Disease ◽  
Coronary Arterial Disease

Association of Green Tea Consumption and Coronary Arterial Disease Risk in a Chinese Population in Guangzhou

2019 ◽  
Vol 25 (4) ◽  
pp. 435-440 ◽  
Author(s):  
Qiuling Xiang ◽  
Jun Pang ◽  
Ying Chen ◽  
Dongxi Hong ◽  
Zhen Zhang ◽  
...  
Keyword(s):  
Green Tea ◽  
Chinese Population ◽  
Disease Risk ◽  
Arterial Disease ◽  
Tea Consumption ◽  
Coronary Arterial Disease

Coronary arterial disease associated with arteriosclerosis in lower extremity: angiographic analysis

1993 ◽  
Vol 29 (6) ◽  
pp. 1163
Author(s):  
Ji Hye Kim ◽  
Jin Wook Chung ◽  
Seon Kyu Lee ◽  
Joon Koo Han ◽  
Jae Hyung Park ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Arterial Disease ◽  
Coronary Arterial Disease

scholarly journals Urinary fatty acid binding protein 3 (uFABP3) is a potential biomarker for peripheral arterial disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Abdelrahman Zamzam ◽  
Muzammil H. Syed ◽  
John Harlock ◽  
John Eikelboom ◽  
Krishna K. Singh ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Arterial Disease ◽  
Prior History ◽  
P Value ◽  
Fatty Acid Binding ◽  
Coronary Arterial Disease ◽  
Acid Binding Protein ◽  
Potential Biomarker

AbstractPlasma levels of fatty acid binding protein 3 (pFABP3) are elevated in patients with peripheral artery disease (PAD). Since the kidney filters FABP3 from circulation, we investigated whether urinary fatty acid binding protein 3 (uFABP3) is associated with PAD, and also explored its potential as a diagnostic biomarker for this disease state. A total of 130 patients were recruited from outpatient clinics at St. Michael’s Hospital, comprising of 65 patients with PAD and 65 patients without PAD (non-PAD). Levels of uFABP3 normalized for urine creatinine (uFABP3/uCr) were 1.7-folds higher in patients with PAD [median (IQR) 4.41 (2.79–8.08)] compared with non-PAD controls [median (IQR) 2.49 (1.78–3.12), p-value = 0.001]. Subgroup analysis demonstrated no significant effect of cardiovascular risk factors (age, sex, hypertension, hypercholesteremia, diabetes and smoking) on uFABP3/uCr in both PAD and non-PAD patients. Spearmen correlation studies demonstrated a significant negative correlation between uFABP3/uCr and ABI (ρ = − 0.436; p-value = 0.001). Regression analysis demonstrated that uFABP3/Cr levels were associated with PAD independently of age, sex, hypercholesterolemia, smoking, prior history of coronary arterial disease and Estimated Glomerular Filtration rate (eGFR) [odds ratio: 2.34 (95% confidence interval: 1.47–3.75) p-value < 0.001]. Lastly, receiver operator curve (ROC) analysis demonstrated unadjusted area under the curve (AUC) for uFABP3/Cr of 0.79, which improved to 0.86 after adjusting for eGFR, age, hypercholesteremia, smoking and diabetes. In conclusion, our results demonstrate a strong association between uFABP3/Cr and PAD and suggest the potential of uFABP3/Cr in identifying patients with PAD.

scholarly journals Brain natriuretic peptide: Diagnostic potential in dogs

2009 ◽  
Vol 63 (5-6) ◽  
pp. 381-392
Author(s):  
Ljubica Spasojevic-Kosic
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Natriuretic Peptides ◽  
Arterial Disease ◽  
Cardiac Insufficiency ◽  
Everyday Clinical Practice ◽  
Coronary Arterial Disease ◽  
Diagnostic Potential ◽  
Adequate Method

The endocrine role of the heart is evident in the secretion of noradrenaline and natriuretic peptides. The secretion of natriuretic peptides presents a useful mechanism for different conditions of cardiac dysfunction. Brain natriuretic peptide (BNP) has been accepted in human cardiology as a biomarker for cardiac insufficiency and coronary arterial disease. The specificity of the BNP structure is specie-specific, so that the testing of diagnostic and prognostic potential in dogs requires the existence of a test that is a homologue for that animal specie. The existence of an adequate method for measuring BNP concentration makes possible its implementation as a screening test in everyday clinical practice. .

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