scholarly journals Splicing mutation analysis reveals previously unrecognized pathways in lymph node-invasive breast cancer

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Stephanie N. Dorman ◽  
Coby Viner ◽  
Peter K. Rogan
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Mutation Analysis ◽  
Invasive Breast Cancer ◽  
Splicing Mutation

scholarly journals Epidemiological and pathological characteristics of post-surgical cases of invasive breast cancer among ethnicities of Iran in 2018: A single center cross-sectional study

2020 ◽  
Vol 26 (1) ◽  
pp. 6-9
Author(s):  
Soheila Sayad ◽  
Seyyed Ahmadi ◽  
Reza Nekouian ◽  
Mahshid Panahi ◽  
Khatereh Anbari
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Invasive Breast Cancer ◽  
Triple Negative ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Single Center ◽  
Cross Sectional ◽  
Familial History ◽  
Number Of Patients

Background: Present study aimed to investigate immunohistochemical parameters in post-surgical cases of invasive breast cancer. Methods: In this single center cross-sectional study we investigated ethnicity, familial history, type of cancer, stage of cancer, lymph node positivity, bilateral involvement, metastasis and immunohistochemical parameters (estrogen and progesterone receptor, human epidermal growth factor receptor 2, as well as frequency of triple positive and triple negative patients merely based on immunohistochemical parameters). Results: Frequency of positive familial history was 27.42% (16.31-38.52%). Lymph node involvement was detected in 55.93% (43.26-68.60%) of the cases. Frequency of positive HER2 was 38.60% (25.96-51.23%). There were 17.54% (7.67-27.42%) of triple positive and 7.02% (0.39-13.65%) of triple negative cases. The most common stage at the time of diagnosis was stage 3 with 43.33% (30.79-55.87%) frequency. In Lur/Lak population higher frequency of positive HER2 cases was detected whereas in Mazani population frequency of positive HER2 cases was low (p=0.0291). Conclusions: These results could contribute to understanding of breast cancer patterns among different ethnicities. In order to draw clear conclusion future investigations have to be done in several health centers, for longer time periods and with larger number of patients.

scholarly journals Prospective multicenter comparison of proliferation and other prognostic factors in lymph node negative lobular invasive breast cancer

2009 ◽  
Vol 121 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Einar Gudlaugsson ◽  
Ivar Skaland ◽  
Emiel A. M. Janssen ◽  
Paul J. van Diest ◽  
Feja J. Voorhorst ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Lymph Node ◽  
Invasive Breast Cancer ◽  
Node Negative
Sign in / Sign up

Export Citation Format

Share Document