scholarly journals Higher omega-3 index is associated with increased insulin sensitivity and more favourable metabolic profile in middle-aged overweight men

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Benjamin B. Albert ◽  
José G. B. Derraik ◽  
Christine M. Brennan ◽  
Janene B. Biggs ◽  
Greg C. Smith ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Metabolic Profile ◽  
Omega 3 ◽  
Middle Aged

scholarly journals Among overweight middle-aged men, first-borns have lower insulin sensitivity than second-borns

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Benjamin B. Albert ◽  
Martin de Bock ◽  
José G. B. Derraik ◽  
Christine M. Brennan ◽  
Janene B. Biggs ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Middle Aged

O2-10-01: OMEGA-3 FATTY ACID LEVELS ARE ASSOCIATED WITH BRAIN MRI MEASURES IN MIDDLE-AGED ADULTS FROM THE FRAMINGHAM HEART STUDY

2006 ◽  
Vol 14 (7S_Part_11) ◽  
pp. P644-P644
Author(s):  
Claudia L. Satizabal ◽  
Jayandra J. Himali ◽  
Alexa S. Beiser ◽  
Ramachandran S. Vasan ◽  
Charlie S. DeCarli ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Framingham Heart Study ◽  
Brain Mri ◽  
Omega 3 ◽  
Middle Aged ◽  
Omega 3 Fatty Acid ◽  
Heart Study ◽  
Middle Aged Adults

scholarly journals Association of Basal Metabolic Rate and Nutrients Oxidation with Cardiometabolic Risk Factors and Insulin Sensitivity in Sedentary Middle-Aged Adults

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1186
Author(s):  
Francisco J. Amaro-Gahete ◽  
Lucas Jurado-Fasoli ◽  
Jonatan R. Ruiz ◽  
Manuel J. Castillo
Keyword(s):  
Risk Factors ◽  
Insulin Sensitivity ◽  
Lean Mass ◽  
Basal Metabolic Rate ◽  
Plasma Insulin ◽  
Cardiometabolic Risk ◽  
Density Lipoprotein ◽  
Cardiometabolic Risk Factors ◽  
Middle Aged ◽  
Middle Aged Adults

This cross-sectional study aimed to examine the association of basal metabolic rate (BMR) and basal fat and carbohydrate oxidation (BFox and BCHox, respectively) with cardiometabolic risk factors and insulin sensitivity in sedentary middle-aged adults. A total of 71 healthy sedentary adults (37 women) aged 40–65 years participated in the current study. Data were collected during the baseline assessments of the FIT-AGEING randomized controlled trial. BMR was measured via indirect calorimetry, and BFox and BCHox estimated by stoichiometric equations. Blood pressure, glucose, insulin, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides plasma levels were selected as cardiometabolic risk factors and assessed following standard procedures. We observed positive associations of BMR with plasma insulin and the homeostatic model assessment of insulin resistance index (HOMA; all p < 0.05) which were attenuated or disappeared after controlling by sex, age, and/or lean mass. There were positive associations between BFox and the quantitative insulin sensitivity check index (QUICKI; p < 0.015), while negative associations were noted between BFox and plasma insulin and HOMA (p < 0.015). There was a significant negative association between BCHox with QUICKI (p < 0.01), whereas significant positive relationships were obtained when BCHox was associated with plasma insulin and HOMA (p < 0.01). These associations persisted in almost all cases when controlling by sex, age and/or lean mass. No further relationships were found when BMR, BFox, and BCHox were associated with other cardiometabolic risk factors. In conclusion, our study findings support that greater BFox and lower BCHox are related to improved insulin sensitivity, whereas BMR seems to be not associated with neither cardiometabolic risk nor insulin sensitivity in sedentary middle-aged adults. Further intervention studies are necessary to well-understand the physiological mechanism implied in this relationship.

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