scholarly journals Effect of additive oxygen gas on cellular response of lung cancer cells induced by atmospheric pressure helium plasma jet

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Hea Min Joh ◽  
Ji Ye Choi ◽  
Sun Ja Kim ◽  
T. H. Chung ◽  
Tae-Hong Kang
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Atmospheric Pressure ◽  
Cellular Response ◽  
Plasma Jet ◽  
Lung Cancer Cells ◽  
Helium Plasma ◽  
Oxygen Gas

Cytoskeletal changes during cellular response of the A549 lung cancer cells to continuous cisplatin treatment

2010 ◽  
Vol 34 (2) ◽  
pp. 197-211 ◽  
Author(s):  
Mariusz Andrzej Szczepański ◽  
Alina Grzanka ◽  
Anna Litwiniec ◽  
Lidia Gackowska ◽  
Izabela Kubiszewska ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Cellular Response ◽  
Lung Cancer Cells ◽  
A549 Lung

Effect of Atmospheric-Pressure Helium Plasma Jet on Cell Culture Medium

2013 ◽  
Vol 133 (5) ◽  
pp. 278-285
Author(s):  
Norimitsu Takamura ◽  
Douyan Wang ◽  
Takao Satoh ◽  
Takao Namihira ◽  
Hisato Saitoh ◽  
...  
Keyword(s):  
Cell Culture ◽  
Atmospheric Pressure ◽  
Culture Medium ◽  
Plasma Jet ◽  
Helium Plasma ◽  
Cell Culture Medium

Inhibitory effects of Actinidia Chinensis planch root extracts (acRoots) on human lung cancer cells through retinoic acid receptor beta

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Lingyan Wang ◽  
Jiayun Hou ◽  
Minghuan Zheng ◽  
Lin Shi
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Human Lung ◽  
Retinoic Acid Receptor ◽  
Lung Cancer Cells ◽  
Human Lung Cancer ◽  
Inhibitory Effects ◽  
The Core ◽  
Human Lung Cancer Cells ◽  
Receptor Beta

Actinidia Chinensis Planch roots (acRoots) are used to treat many cancers, although the anti-tumor mechanism by which acRoots inhibit cancer cell growth remains unclear. The present study aims at investigating inhibitory effects of acRoots on human lung cancer cells and potential mechanisms. Our data demonstrate that the inhibitory effects of acRoots on lung cancer cells depend on genetic backgrounds and phenotypes of cells. We furthermore found the expression of metabolism-associated gene profiles varied between acRoots-hypersensitive (H460) or hyposensitive lung cancer cells (H1299) after screening lung cancer cells with different genetic backgrounds. We selected retinoic acid receptor beta (RARB) as the core target within metabolism-associated core gene networks and evaluated RARB changes and roles in cells treated with acRoots at different concentrations and timeframes. Hypersensitive cancer cells with the deletion of RARB expression did not response to the treatment with acRoots, while RARB deletion did not change effects of acRoots on hyposensitive cells. Thus, it seems that RARB as the core target within metabolism-associated networks plays important roles in the regulation of lung cancer cell sensitivity to acRoots.

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