scholarly journals Natural channel protein inserts and functions in a completely artificial, solid-supported bilayer membrane

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Xiaoyan Zhang ◽  
Wangyang Fu ◽  
Cornelia G. Palivan ◽  
Wolfgang Meier
Keyword(s):  
Bilayer Membrane ◽  
Channel Protein ◽  
Supported Bilayer ◽  
Natural Channel

Pulling on a Sphere Adhering to a Supported Bilayer Membrane

Langmuir ◽  
2000 ◽  
Vol 16 (7) ◽  
pp. 2991-2994 ◽  
Author(s):  
C. Tordeux ◽  
J.-B. Fournier
Keyword(s):  
Bilayer Membrane ◽  
Supported Bilayer

Order at the Edge of the Bilayer: Membrane Remodeling at the Edge of a Planar Supported Bilayer Is Accompanied by a Localized Phase Change

2010 ◽  
Vol 132 (27) ◽  
pp. 9320-9327 ◽  
Author(s):  
Andreia M. Smith ◽  
Madhuri Vinchurkar ◽  
Niels Gronbech-Jensen ◽  
Atul N. Parikh
Keyword(s):  
Phase Change ◽  
Bilayer Membrane ◽  
Membrane Remodeling ◽  
Supported Bilayer

Recent Advances in Novasome Formulation Technology

2014 ◽  
Vol 7 (2) ◽  
pp. 2407-2411
Author(s):  
J M Shah ◽  
N.H Shah ◽  
Hadiya P D
Keyword(s):  
Drug Delivery ◽  
Effective Means ◽  
Entrapment Efficiency ◽  
Bilayer Membrane ◽  
Water Soluble ◽  
Delivery Methods ◽  
Liposomal Drug ◽  
Pharmaceutical Technology ◽  
Insoluble Drugs ◽  
Novel Drug

Pharmaceutical technology has developed various newer modes of novel drug delivery aspects. Modifications in the previously existing drug delivery methods have led to various newly innovated technologies serving as a safe and effective means of improvement over the existing ones. Novasome technology is one of the new innovations of liposomes which have solved many of the problems related to liposomal drug delivery system. It offers a seven bilayer membrane which has the ability to incorporate both water soluble and insoluble drugs. It has an excellent entrapment efficiency which provides better medication. Formulation of novasomes is achieved in a high shear device. Due to its numerous advantages, novasomes have been used extensively in various fields like cosmetics, chemical, personal care, foods, pharmaceuticals and agrochemicals.

Excitation of Bilayer Membrane

1969 ◽  
Vol 9 (2) ◽  
pp. 49-66
Author(s):  
Masayuki TAKAGI
Keyword(s):  
Bilayer Membrane

scholarly journals Transmembrane signal transduction by cofactor transport

2021 ◽  
Author(s):  
Istvan Kocsis ◽  
Yudi Ding ◽  
Nicholas H. Williams ◽  
Christopher A. Hunter
Keyword(s):  
Signal Transduction ◽  
Lipid Bilayer ◽  
Metal Ion ◽  
Bilayer Membrane ◽  
Ester Hydrolysis ◽  
Lipid Bilayer Membrane ◽  
Metal Ion Cofactors

Synthetic transducers transport externally added metal ion cofactors across the lipid bilayer membrane of vesicles to trigger catalysis of ester hydrolysis in the inner compartment. Signal transduction activity is modulated by hydrazone formation.

scholarly journals Evaluation of the correlation between porphyrin accumulation in cancer cells and functional positions for application as a drug carrier

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Koshi Nishida ◽  
Toshifumi Tojo ◽  
Takeshi Kondo ◽  
Makoto Yuasa
Keyword(s):  
Cancer Cells ◽  
Drug Carrier ◽  
Bilayer Membrane ◽  
Phospholipid Bilayer ◽  
Membrane Permeation ◽  
Porphyrin Derivatives ◽  
Phospholipid Bilayer Membrane ◽  
Meso Position ◽  
Tumor Accumulation ◽  
Binding Position

AbstractPorphyrin derivatives accumulate selectively in cancer cells and are can be used as carriers of drugs. Until now, the substituents that bind to porphyrins (mainly at the meso-position) have been actively investigated, but the effect of the functional porphyrin positions (β-, meso-position) on tumor accumulation has not been investigated. Therefore, we investigated the correlation between the functional position of substituents and the accumulation of porphyrins in cancer cells using cancer cells. We found that the meso-derivative showed higher accumulation in cancer cells than the β-derivative, and porphyrins with less bulky substituent actively accumulate in cancer cells. When evaluating the intracellular distribution of porphyrin, we found that porphyrin was internalized by endocytosis and direct membrane permeation. As factors involved in these two permeation mechanisms, we evaluated the affinity between porphyrin-protein (endocytosis) and the permeability to the phospholipid bilayer membrane (direct membrane permeation). We found that the binding position of porphyrin affects the factors involved in the transmembrane permeation mechanisms and impacts the accumulation in cancer cells.

scholarly journals Alpha-dendrotoxin acceptor from bovine brain is a K+ channel protein. Evidence from the N-terminal sequence of its larger subunit

1990 ◽  
Vol 265 (33) ◽  
pp. 20094-20097
Author(s):  
V E Scott ◽  
D N Parcej ◽  
J N Keen ◽  
J B Findlay ◽  
J O Dolly
Keyword(s):  
Bovine Brain ◽  
K Channel ◽  
Terminal Sequence ◽  
Channel Protein
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