scholarly journals Screening for neuropathic pain after spinal cord injury with the Spinal Cord Injury Pain Instrument (SCIPI): a preliminary validation study

Spinal Cord ◽  
2014 ◽  
Vol 52 (5) ◽  
pp. 407-412 ◽  
Author(s):  
T N Bryce ◽  
J S Richards ◽  
C H Bombardier ◽  
M P Dijkers ◽  
J R Fann ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Validation Study ◽  
Preliminary Validation ◽  
Cord Injury ◽  
Spinal Cord Injury Pain

Poster 20 Preliminary Validation of the Spinal Cord Injury Pain Instrument (SCIPI), a Neuropathic Pain Screening tool

2013 ◽  
Vol 94 (10) ◽  
pp. e19
Author(s):  
Thomas Bryce ◽  
J Scott Richards ◽  
Marcel PJM. Dijkers ◽  
Larry Brooks ◽  
Jesse R. Fann ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Screening Tool ◽  
Preliminary Validation ◽  
Cord Injury ◽  
Spinal Cord Injury Pain

Neuropathic pain following spinal cord injury pain: mechanisms and treatment

2009 ◽  
Vol 1 ◽  
pp. S3-S11 ◽  
Author(s):  
Nanna Brix Finnerup ◽  
Cathrine Baastrup ◽  
Troels Staehelin Jensen
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Pain Mechanisms ◽  
Cord Injury ◽  
Spinal Cord Injury Pain

Intravenous Lidocaine Relieves Spinal Cord Injury Pain

2005 ◽  
Vol 102 (5) ◽  
pp. 1023-1030 ◽  
Author(s):  
Nanna B. Finnerup ◽  
Fin Biering-Sørensen ◽  
Inger L. Johannesen ◽  
Astrid J. Terkelsen ◽  
Gitte I. Juhl ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Sodium Channel ◽  
Spontaneous Pain ◽  
Channel Blockers ◽  
Double Blind ◽  
Cord Injury ◽  
Predictive Role ◽  
Spinal Cord Injury Pain

Background Neuropathic pain in spinal cord injury is a common challenging therapeutic condition. The current study examines the analgesic effect of the sodium channel blocker lidocaine on neuropathic pain in patients with spinal cord injury and the predictive role of concomitant evoked pain on pain relief with lidocaine. Methods Twenty-four spinal cord injury patients with neuropathic pain at or below the level of injury were randomized and completed a double-blind crossover trial of 5 mg/kg lidocaine and placebo infused over 30 min. Twelve patients reported evoked pain, and 12 patients had no evoked pain. Spontaneous and evoked pains were assessed using a visual analog scale and quantitative sensory testing. Results Lidocaine significantly reduced spontaneous pain in all patients (P < 0.01) and in each of the two groups with (P < 0.01) and without (P = 0.048) evoked pain, with no difference in number of responders (pain reduction > or = 33%) between the patients with (n = 6) and without (n = 5) evoked pain. Lidocaine significantly relieved both at-level and below-level neuropathic pain and decreased brush-evoked dysesthesia but not cold allodynia, pinprick hyperalgesia, or pain evoked by repetitive pinprick. Conclusions Lidocaine reduced neuropathic pain at and below the level of injury irrespective of the presence or absence of evoked pain. Results are consistent with a central-acting effect of sodium channel blockers acting on neuronal hyperexcitability. Agents (such as anticonvulsants or antiarrhythmics) with sodium channel-blocking properties may be a treatment option for spinal cord injury pain.

scholarly journals 1-kHz high-frequency spinal cord stimulation alleviates chronic refractory pain after spinal cord injury: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Chiaki Yamada ◽  
Aiko Maeda ◽  
Katsuyuki Matsushita ◽  
Shoko Nakayama ◽  
Kazuhiro Shirozu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Spinal Cord Stimulation ◽  
High Frequency ◽  
Cervical Vertebrae ◽  
Intractable Pain ◽  
Target Area ◽  
Positive Effects ◽  
Cord Injury

Abstract Background Patients with spinal cord injury (SCI) frequently complain of intractable pain that is resistant to conservative treatments. Here, we report the successful application of 1-kHz high-frequency spinal cord stimulation (SCS) in a patient with refractory neuropathic pain secondary to SCI. Case presentation A 69-year-old male diagnosed with SCI (C4 American Spinal Injury Association Impairment Scale A) presented with severe at-level bilateral upper extremity neuropathic pain. Temporary improvement in his symptoms with a nerve block implied peripheral component involvement. The patient received SCS, and though the tip of the leads could not reach the cervical vertebrae, a 1-kHz frequency stimulus relieved the intractable pain. Conclusions SCI-related symptoms may include peripheral components; SCS may have a considerable effect on intractable pain. Even when the SCS electrode lead cannot be positioned in the target area, 1-kHz high-frequency SCS may still produce positive effects.

Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury

2021 ◽  
Author(s):  
Andrew D. Gaudet ◽  
Laura K. Fonken ◽  
Monica T. Ayala ◽  
Steven F. Maier ◽  
Linda R. Watkins
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Cord Injury
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