scholarly journals Diffusion-weighted MR imaging within 24 h post-injury after traumatic spinal cord injury: a qualitative meta-analysis between T2-weighted imaging and diffusion-weighted MR imaging in 18 patients

Spinal Cord ◽  
2012 ◽  
Vol 50 (6) ◽  
pp. 426-431 ◽  
Author(s):  
M H Pouw ◽  
A M van der Vliet ◽  
A van Kampen ◽  
M M Thurnher ◽  
H van de Meent ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mr Imaging ◽  
Meta Analysis ◽  
Traumatic Spinal Cord Injury ◽  
Post Injury ◽  
Diffusion Weighted ◽  
Cord Injury ◽  
And Diffusion

MR Imaging for Assessing Injury Severity and Prognosis in Acute Traumatic Spinal Cord Injury

2019 ◽  
Vol 57 (2) ◽  
pp. 319-339 ◽  
Author(s):  
Jason F. Talbott ◽  
John Russell Huie ◽  
Adam R. Ferguson ◽  
Jacqueline C. Bresnahan ◽  
Michael S. Beattie ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mr Imaging ◽  
Injury Severity ◽  
Traumatic Spinal Cord Injury ◽  
Cord Injury

scholarly journals Axonal degeneration and demyelination following traumatic spinal cord injury: A systematic review and meta-analysis

2019 ◽  
Vol 97 ◽  
pp. 9-22 ◽  
Author(s):  
Zahra Hassannejad ◽  
Mahmoud Yousefifard ◽  
Yaser Azizi ◽  
Shayan Abdollah Zadegan ◽  
Kiavash Sajadi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Axonal Degeneration ◽  
Meta Analysis ◽  
Traumatic Spinal Cord Injury ◽  
Cord Injury

The Impact of Urgent (<8 Hours) Decompression on Neurologic Recovery in Traumatic Spinal Cord Injury: A Meta-Analysis

2020 ◽  
Vol 140 ◽  
pp. e185-e194
Author(s):  
Yihang Ma ◽  
Yuhang Zhu ◽  
Boyin Zhang ◽  
Yuntao Wu ◽  
Xiangji Liu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Meta Analysis ◽  
Traumatic Spinal Cord Injury ◽  
Neurologic Recovery ◽  
Cord Injury ◽  
The Impact

scholarly journals Mesenchymal stem cells promote augmented response of endogenous neural stem cells in spinal cord injury of rats

2016 ◽  
Vol 37 (3) ◽  
pp. 1355 ◽  
Author(s):  
Marta Rocha Araujo ◽  
Pablo Herthel Carvalho ◽  
Taís Silva de Paula ◽  
Bárbara Silva Okano ◽  
Ricardo Junqueira Del Carlo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Mesenchymal Stem Cells ◽  
Experimental Models ◽  
Neurological Deficits ◽  
Traumatic Spinal Cord Injury ◽  
Post Injury ◽  
Cord Injury ◽  
Significant Attenuation

Traumatic spinal cord injury results in severe neurological deficits, mostly irreversible. The cell therapy represents a strategy for treatment particularly with the use of stem cells with satisfactory results in several experimental models. The aim of the study was to compare the treatment of spinal cord injury (SCI) with and without mesenchymal stem cells (MSC), to investigate whether MSCs migrate and/or remain at the site of injury, and to analyze the effects of MSCs on inflammation, astrocytic reactivity and activation of endogenous stem cells. Three hours after SCI, animals received bone marrow-derived MSCs (1×107 in 1mL PBS, IV). Animals were euthanized 24 hours, 7 and 21 days post-injury. The MSC were not present in the site of the lesion and the immunofluorescent evaluation showed significant attenuation of inflammatory response with reduction in macrophages labeled with anti-CD68 antibody (ED1), decreased immunoreactivity of astrocytes (GFAP+) and greater activation of endogenous stem cells (nestin+) in the treated groups. Therefore, cell transplantation have a positive effect on recovery from traumatic spinal cord injury possibly due to the potential of MSCs to attenuate the immune response.

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