scholarly journals Autonomic function after spinal cord lesion: animal guidelines and international standards

Spinal Cord ◽  
2009 ◽  
Vol 47 (1) ◽  
pp. 1-1 ◽  
Author(s):  
J J Wyndaele
Keyword(s):  
Spinal Cord ◽  
Autonomic Function ◽  
Spinal Cord Lesion ◽  
Lesion Animal ◽  
International Standards ◽  
Cord Lesion

Alteraciones sistémicas y metabólicas producidas por lesión medular

2019 ◽  
Vol 1 (1) ◽  
pp. 59-75
Author(s):  
Gabriel Guízar Sahagún
Keyword(s):  
Spinal Cord ◽  
Daily Living ◽  
Autonomic Function ◽  
Clinical Presentation ◽  
Scientific Literature ◽  
International Standards ◽  
Therapeutic Approaches ◽  
Cord Injury ◽  
Life Threatening ◽  
The Impact

Besides the well-known loss of motor and sensory capabilities, people with spinal cord injury (SCI) experience a broad range of systemic and metabolic abnormalities including, among others, dysfunction of cardiovascular, respiratory, gastrointestinal, urinary, and endocrine systems. These alterations are a significant challenge for patients with SCI because such disorders severely interfere with their daily living and can be potentially life-threatening. Most of these disorders are associated with impairment of regulation of the autonomic nervous system, arising from disruption of connections between higher brain centers and the spinal cord caudal to the injured zone. Thus, the higher and more complete the lesion, the greater the autonomic dysfunction and the severity of complications.This article summarizes the medical scientific literature on key systemic and metabolic alterations derived of SCI. It provides information primarily focused on the pathophysiology and clinical presentation of these disorders, as well as some guides to prevent and alleviate such complications. Due to the impact of these alterations, this topic must be a priority and diffuse to those involved with the care of people with SCI, including the patient himself/herself. We consider that any collaborative effort should be supported, like the development of international standards, to evaluate autonomic function after SCI, as well as the development of novel therapeutic approaches.

scholarly journals Anti-amphiphysin antibody-positive paraneoplastic neurological syndrome with a longitudinally extensive spinal cord lesion of the dorsal column

2014 ◽  
Vol 54 (7) ◽  
pp. 572-576 ◽  
Author(s):  
Shuichiro Neshige ◽  
Naoyuki Hara ◽  
Shinichi Takeshima ◽  
Hirotaka Iwaki ◽  
Yutaka Shimoe ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Paraneoplastic Neurological Syndrome ◽  
Dorsal Column ◽  
Spinal Cord Lesion ◽  
Neurological Syndrome ◽  
Cord Lesion

Cross-cultural adaptation of the spinal cord lesion-related coping strategies questionnaire for use in Iran

Injury ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. 1539-1544 ◽  
Author(s):  
Mohsen Saffari ◽  
Amir H. Pakpour ◽  
Mohammad Yaghobidoot ◽  
Faten Al Zaben ◽  
Harold G. Koenige
Keyword(s):  
Spinal Cord ◽  
Coping Strategies ◽  
Cultural Adaptation ◽  
Spinal Cord Lesion ◽  
Cross Cultural ◽  
Cross Cultural Adaptation ◽  
Cord Lesion

Reduction of Common Synaptic Drive to Ankle Dorsiflexor Motoneurons During Walking in Patients With Spinal Cord Lesion

2005 ◽  
Vol 94 (2) ◽  
pp. 934-942 ◽  
Author(s):  
N. L. Hansen ◽  
B. A. Conway ◽  
D. M. Halliday ◽  
S. Hansen ◽  
H. S. Pyndt ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Motor Unit ◽  
Healthy Subjects ◽  
Motor Units ◽  
Central Peak ◽  
Spinal Cord Lesion ◽  
Short Term ◽  
Physiological Markers ◽  
Synaptic Drive ◽  
Cord Lesion

It is possible to obtain information about the synaptic drive to motoneurons during walking by analyzing motor-unit coupling in the time and frequency domains. The purpose of the present study was to compare motor-unit coupling during walking in healthy subjects and patients with incomplete spinal cord lesion to obtain evidence of differences in the motoneuronal drive that result from the lesion. Such information is of importance for development of new strategies for gait restoration. Twenty patients with incomplete spinal cord lesion (SCL) participated in the study. Control experiments were performed in 11 healthy subjects. In all healthy subjects, short-term synchronization was evident in the discharge of tibialis anterior (TA) motor units during the swing phase of treadmill walking. This was identified from the presence of a narrow central peak in cumulant densities constructed from paired EMG recordings and from the presence of significant coherence between these signals in the 10- to 20-Hz band. Such indicators of short-term synchrony were either absent or very small in the patient group. The relationship between the amount of short-term synchrony and the magnitude of the 10- to 20-Hz coherence in the patients is discussed in relation to gait ability. It is suggested that supraspinal drive to the spinal cord is responsible for short-term synchrony and coherence in the 10- to 20-Hz frequency band during walking in healthy subjects. Absence or reduction of these features may serve as physiological markers of impaired supraspinal control of gait in SCL patients. Such markers could have diagnostic and prognostic value in relation to the recovery of locomotion in patients with central motor lesions.

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