scholarly journals Greatly improved sperm motility from vas deferens sperm retrieval: a case for accessory gland related subfertility in spinal cord injured man

Spinal Cord ◽  
1994 ◽  
Vol 32 (7) ◽  
pp. 501-504 ◽  
Author(s):  
J P Buch
2000 ◽  
pp. 712-715 ◽  
Author(s):  
NANCY L. BRACKETT ◽  
CHARLES M. LYNNE ◽  
TEODORO C. ABALLA ◽  
SEAN M. FERRELL

2000 ◽  
Vol 164 (3 Part 1) ◽  
pp. 712-715 ◽  
Author(s):  
NANCY L. BRACKETT ◽  
CHARLES M. LYNNE ◽  
TEODORO C. ABALLA ◽  
SEAN M. FERRELL

Author(s):  
Mikkel Fode ◽  
Jens Sønksen

While spinal cord injury (SCI) does not affect female fertility, the condition most often results in infertility in males due to anejaculation and reduced semen quality. Anejaculation is caused by disruption of the autonomic nerve fibres, which are normally responsible for the ejaculation. The reason for the poor sperm quality has not been firmly established. If spinal cord injured men cannot ejaculate by sexual intercourse or masturbation, ejaculation can be induced by either penile vibratory stimulation or electroejaculation. Only if these methods fail should surgical sperm retrieval be considered. The method of insemination depends largely on the total motile sperm count and patient preference. With the right treatment, it is possible for most SCI men to have children.


2006 ◽  
Vol 22 (5) ◽  
pp. 252-255 ◽  
Author(s):  
Yaprak Engin-Üstün ◽  
Cem Korkmaz ◽  
Namik Kemal Duru ◽  
İskender Başer

1996 ◽  
pp. 1632-1635 ◽  
Author(s):  
Nancy L. Brackett ◽  
Richard C. Davi ◽  
Osvaldo F. Padron ◽  
Charles M. Lynne

1996 ◽  
Vol 155 (5) ◽  
pp. 1632-1635 ◽  
Author(s):  
Nancy L. Brackett ◽  
Richard C. Davi ◽  
Osvaldo F. Padron ◽  
Charles M. Lynne

2019 ◽  
Vol 86 (3) ◽  
pp. 141-144
Author(s):  
Gianmartin Cito ◽  
Maria Elisabetta Coccia ◽  
Francesco Bertocci ◽  
Rita Picone ◽  
Andrea Cocci ◽  
...  

Introduction: Infertility may depend up to 27% of couples on both partners. In patients with obstructive azoospermia, testicular fine-needle aspiration represents a good option to retrieve spermatozoa, in order to perform an assisted reproductive treatment. In vitro maturation of testicular spermatozoa could be the better choice of treatment in view of the increased motility, improving fertilization and pregnancy rates. Case description: A 34-year-old azoospermic man and his 33-year-old partner referred for treatment of simultaneous male and female infertility factor. The woman presented a diminished ovarian reserve, with serum follicle stimulating hormone value of 27.15 IU/L. The man underwent trans-rectal and testicular ultrasounds that detected the congenital absence of proximal vas deferens on the right side and the absence of seminal vesicle and distal vas deferens on the left side. We proposed a chance to have their own biological child. The man underwent modified testicular fine-needle aspiration using a 18-gauge butterfly needle. Sperm retrieval was successful with 0.001 × 106 spermatozoa/mL and absence of motility. Testicular sperm suspension was cultured for 24 h to identify sperm viability, achieving 10% of sperm motility. Two metaphase II oocytes were retrieved and processed with intracytoplasmic sperm injection. Clinical pregnancy with live birth was obtained. Conclusion: Performing modified testicular fine-needle aspiration increases successful sperm retrieval. Testicular sperm in vitro culture for 24 h proved to be a real and practical technique to increase sperm motility, in order to select mature and viable spermatozoa and improve successful intracytoplasmic sperm injection outcomes.


2019 ◽  
Vol 26 (2) ◽  
Author(s):  
Aditya Pramanta ◽  
Johan Renaldo ◽  
Doddy M Soebadi

Objective: The patency rates after vasectomy reversal ranges from 71-97%, but there is 26-72% possibility of persistent infertility. Dysfunction or obstruction of the epididymis and oxidative stress are thought to be the important cause of male infertility by disrupting spermatozoa maturation process, causing poor sperm quality. Human erythropoietin or better known as EPO is a glycoprotein hormone that has been purified since three decades ago. Research on the EPO has evolved and become a major research topic the researchers aimed as a therapeutic agent. The cloning and expression of erythropoietin has developed recombinant erythropoietin as a drug that serves as an anti-oxidant, anti-apoptotic and anti-inflammatory. This study aimed to determine the effect of erythropoietin supplementation on sperm motility and morphology in Wistar rat after the release of the vas deferens’ ligation. Material & Methods: Twenty four male Wistar rats were randomly divided into four groups (6 each). On the vasectomy group, the vas deferens were serially ligated for 7 weeks using a non-absorbable suture. The vasectomy reversal group get the same surgical treatment and after 7 weeks the ligation were released. While as in the erythropoietin group, recombinant eryhtropoietin (1000 IU/kg) was administered intraperitoneally three times for 1 week after releasing the ligation. Normal control animals received no surgical manipulation and followed by sperm retrieval for analysis. Eosin-stained slides were prepared to assess the motility and morphology of sperm cells and observed under a light microscope. Results: Ligation of vas deferens significantly decreased sperm motility and morphology. Releasing the ligation of the vas deferens did not improve the sperm motility and morphology. Supplementing eryhtropoietin 1000 IU/kg 3 times for a week after releasing the ligation did not improve the sperm motility and morphology. Conclusion: Erythropoietin supplementation did not improve the sperm motility and morphology in Wistar rat after releasing the ligation of vas deferens.


2004 ◽  
Author(s):  
Leif Sandsjo ◽  
Lena Grundell ◽  
Kirsi Valtonen ◽  
Ann-Katrin Karlsson ◽  
Eira Viikari-Juntura

Sign in / Sign up

Export Citation Format

Share Document