scholarly journals Multiscale Kinetic Modeling of Liposomal Doxorubicin Delivery Quantifies the Role of Tumor and Drug-Specific Parameters in Local Delivery to Tumors

2012 ◽  
Vol 1 (11) ◽  
pp. 15 ◽  
Author(s):  
BS Hendriks ◽  
JG Reynolds ◽  
SG Klinz ◽  
E Geretti ◽  
H Lee ◽  
...  
Keyword(s):  
Kinetic Modeling ◽  
Liposomal Doxorubicin ◽  
Local Delivery ◽  
Doxorubicin Delivery

scholarly journals Arsenic Removal by Advanced Electrocoagulation Processes: The Role of Oxidants Generated and Kinetic Modeling

Catalysts ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 928
Author(s):  
Micah Flor V. Montefalcon ◽  
Meliton R. Chiong ◽  
Augustus C. Resurreccion ◽  
Sergi Garcia-Segura ◽  
Joey D. Ocon
Keyword(s):  
Kinetic Modeling ◽  
Arsenic Removal ◽  
Fold Increase ◽  
Electrochemical Treatment ◽  
Promising Alternative ◽  
Iron Electrodes ◽  
Removal Capacity ◽  
Naturally Occurring ◽  
Treatment Technologies

Arsenic (As) is a naturally occurring element in the environment that poses significant risks to human health. Several treatment technologies have been successfully used in the treatment of As-contaminated waters. However, limited literature has explored advanced electrocoagulation (EC) processes for As removal. The present study evaluates the As removal performance of electrocoagulation, electrochemical peroxidation (ECP), and photo-assisted electrochemical peroxidation (PECP) technologies at circumneutral pH using electroactive iron electrodes. The influence of As speciation and the role of oxidants in As removal were investigated. We have identified the ECP process to be a promising alternative for the conventional EC with around 4-fold increase in arsenic removal capacity at a competitive cost of 0.0060 $/m3. Results also indicated that the rate of As(III) oxidation at the outset of electrochemical treatment dictates the extent of As removal. Both ECP and PECP processes reached greater than 96% As(III) conversion at 1 C/L and achieved 86% and 96% As removal at 5 C/L, respectively. Finally, the mechanism of As(III) oxidation was evaluated, and results showed that Fe(IV) is the intermediate oxidant generated in advanced EC processes, and the contribution of •OH brought by UV irradiation is insignificant.

scholarly journals Low Intensity Ultrasound Mediated Liposomal Doxorubicin Delivery Using Polymer Microbubbles

2015 ◽  
Vol 13 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Francois T. H. Yu ◽  
Xucai Chen ◽  
Jianjun Wang ◽  
Bin Qin ◽  
Flordeliza S. Villanueva
Keyword(s):  
Liposomal Doxorubicin ◽  
Low Intensity ◽  
Low Intensity Ultrasound ◽  
Doxorubicin Delivery

scholarly journals Physiological Role of Kv1.3 Channel in T Lymphocyte Cell Investigated Quantitatively by Kinetic Modeling

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e89975 ◽  
Author(s):  
Panpan Hou ◽  
Rong Zhang ◽  
Yongfeng Liu ◽  
Jing Feng ◽  
Wei Wang ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Kinetic Modeling ◽  
Physiological Role ◽  
Kv1.3 Channel ◽  
Lymphocyte Cell

scholarly journals Downstream Paradigm in Enamine Catalysis: Comment on “On Stereocontrol in Organocatalytic α-Chlorinations of Aldehydes”

2021 ◽  
Author(s):  
Jordi Bures ◽  
Alan Armstrong ◽  
Donna Blackmond
Keyword(s):  
Kinetic Modeling ◽  
Catalytic Cycle ◽  
Enamine Catalysis

<p>We present kinetic modeling results in order to evaluate different mechanistic proposals that have been presented concerning the role of “downstream intermediates” in enamine catalysis. The focus of the debate is the identity and role of aminal intermediates. Are the aminals <i>syn</i> or are they <i>anti</i>, or are both observed? Do they lie on the catalytic cycle, as we suggest, or are they off-cycle species?</p>

Sign in / Sign up

Export Citation Format

Share Document