scholarly journals Graded oxygen saturation targets and retinopathy of prematurity in extremely preterm infants

2016 ◽  
Vol 80 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Rowena Cayabyab ◽  
Vasudha Arora ◽  
Fiona Wertheimer ◽  
Manuel Durand ◽  
Rangasamy Ramanathan
Keyword(s):  
Oxygen Saturation ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

scholarly journals Risk Factors Associated with Retinopathy of Prematurity in Very and Extremely Preterm Infants

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 420
Author(s):  
Claudia Ioana Borțea ◽  
Florina Stoica ◽  
Marioara Boia ◽  
Emil Radu Iacob ◽  
Mihai Dinu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Univariate Analysis ◽  
Significant Risk ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Surfactant Administration ◽  
Stage 1

Background and Objectives: Retinopathy of prematurity (ROP) is the leading cause of blindness in preterm infants. We studied the relationship between different perinatal characteristics, i.e., sex; gestational age (GA); birth weight (BW); C-reactive protein (CRP) and lactate dehydrogenase (LDH) concentrations; ventilation, continuous positive airway pressure (CPAP), and surfactant administration; and the incidence of Stage 1–3 ROP. Materials and Methods: This study included 247 preterm infants with gestational age (GA) < 32 weeks that were successfully screened for ROP. Univariate and multivariate binary analyses were performed to find the most significant risk factors for ROP (Stage 1–3), while multivariate multinomial analysis was used to find the most significant risk factors for specific ROP stages, i.e., Stage 1, 2, and 3. Results: The incidence of ROP (Stage 1–3) was 66.40% (164 infants), while that of Stage 1, 2, and 3 ROP was 15.38% (38 infants), 27.53% (68 infants), and 23.48% (58 infants), respectively. Following univariate analysis, multiple perinatal characteristics, i.e., GA; BW; and ventilation, CPAP, and surfactant administration, were found to be statistically significant risk factors for ROP (p < 0.001). However, in a multivariate model using the same characteristics, only BW and ventilation were significant ROP predictors (p < 0.001 and p < 0.05, respectively). Multivariate multinomial analysis revealed that BW was only significantly correlated with Stage 2 and 3 ROP (p < 0.05 and p < 0.001, respectively), while ventilation was only significantly correlated with Stage 2 ROP (p < 0.05). Conclusions: The results indicate that GA; BW; and the use of ventilation, CPAP, and surfactant were all significant risk factors for ROP (Stage 1–3), but only BW and ventilation were significantly correlated with ROP and specific stages of the disease, namely Stage 2 and 3 ROP and Stage 2 ROP, respectively, in multivariate models.

scholarly journals Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration

JAMA ◽  
2018 ◽  
Vol 319 (21) ◽  
pp. 2190 ◽  
Author(s):  
Lisa M. Askie ◽  
Brian A. Darlow ◽  
Neil Finer ◽  
Barbara Schmidt ◽  
Ben Stenson ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Preterm Infants ◽  
Meta Analysis ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

Increased 36-Week Survival with High Oxygen Saturation Target in Extremely Preterm Infants

2011 ◽  
Vol 364 (17) ◽  
pp. 1680-1682 ◽  
Author(s):  
Ben Stenson ◽  
Peter Brocklehurst ◽  
William Tarnow-Mordi
Keyword(s):  
Oxygen Saturation ◽  
Preterm Infants ◽  
High Oxygen ◽  
Extremely Preterm ◽  
Extremely Preterm Infants

Effect of fluctuation of oxygenation on the development of severe retinopathy of prematurity in extremely preterm infants

2020 ◽  
Vol 40 (3) ◽  
pp. 515-521
Author(s):  
Yousuke Imanishi ◽  
Katsuya Hirata ◽  
Masatoshi Nozaki ◽  
Narutaka Mochizuki ◽  
Shinya Hirano ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Extremely Preterm ◽  
Extremely Preterm Infants
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