scholarly journals Inhibition of heme oxygenase activity using a microparticle formulation of zinc protoporphyrin in an acute hemolytic newborn mouse model

2015 ◽  
Vol 79 (2) ◽  
pp. 251-257 ◽  
Author(s):  
Kazumichi Fujioka ◽  
Flora Kalish ◽  
Ronald J. Wong ◽  
David K. Stevenson
Keyword(s):  
Mouse Model ◽  
Heme Oxygenase ◽  
Zinc Protoporphyrin ◽  
Newborn Mouse ◽  
Heme Oxygenase Activity ◽  
Oxygenase Activity

Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model

Neonatology ◽  
2017 ◽  
Vol 112 (4) ◽  
pp. 376-383 ◽  
Author(s):  
Stephanie Kourula ◽  
Joyce Ang ◽  
Hui Zhao ◽  
Flora Kalish ◽  
Peter Vandenabeele ◽  
...  
Keyword(s):  
Mouse Model ◽  
Heme Oxygenase ◽  
Neonatal Mouse ◽  
Heme Binding ◽  
Heme Oxygenase Activity ◽  
Oxygenase Activity

scholarly journals Suppression of hyperbilirubinemia in the rat neonate by chromium-protoporphyrin. Interactions of metalloporphyrins with microsomal heme oxygenase of human spleen.

1982 ◽  
Vol 156 (6) ◽  
pp. 1878-1883 ◽  
Author(s):  
G S Drummond ◽  
A Kappas
Keyword(s):  
Single Dose ◽  
Heme Oxygenase ◽  
Competitive Inhibitor ◽  
Bile Pigment ◽  
Human Spleen ◽  
Oxidation Activity ◽  
Heme Oxygenase Activity ◽  
Heme Degradation ◽  
Oxygenase Activity ◽  
Liver And Kidney

The synthetic metalloporphyrin, Cr-protoporphyrin, as a potent competitive inhibitor of heme oxygenase activity in rat spleen, liver, and kidney. When administered to neonatal animals in a single dose immediately after birth, Cr-protoporphyrin suppresses postnatal hyperbilirubinemia and produces a marked and sustained lowering of heme oxidation activity in liver, spleen, and kidney. The metalloporphyrin also potently inhibited the rate of heme degradation to bile pigment in human spleen.

Heme oxygenase activity causes transient hypersensitivity to oxidative ultraviolet a radiation that depends on release of iron from heme

2000 ◽  
Vol 28 (8) ◽  
pp. 1191-1196 ◽  
Author(s):  
Egil Kvam ◽  
Vidya Hejmadi ◽  
Stefan Ryter ◽  
Charareh Pourzand ◽  
Rex M Tyrrell
Keyword(s):  
Heme Oxygenase ◽  
Ultraviolet A ◽  
Heme Oxygenase Activity ◽  
Oxygenase Activity

scholarly journals Heme oxygenase activity and hemoglobin neurotoxicity are attenuated by inhibitors of the MEK/ERK pathway

2009 ◽  
Vol 56 (5) ◽  
pp. 922-928 ◽  
Author(s):  
Jing Chen-Roetling ◽  
Zhi Li ◽  
Mai Chen ◽  
Olatilewa O. Awe ◽  
Raymond F. Regan
Keyword(s):  
Heme Oxygenase ◽  
Erk Pathway ◽  
Heme Oxygenase Activity ◽  
Oxygenase Activity
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