scholarly journals Prediction of neurodevelopmental outcome after hypoxic–ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics

2012 ◽  
Vol 72 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Nora Tusor ◽  
Courtney Wusthoff ◽  
Natalie Smee ◽  
Nazakat Merchant ◽  
Tomoki Arichi ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Spatial Statistics ◽  
Diffusion Tensor ◽  
Neurodevelopmental Outcome ◽  
Hypoxic Ischemic Encephalopathy ◽  
Tract Based Spatial Statistics ◽  
Ischemic Encephalopathy

scholarly journals Correlation Between White Matter Injury Identified by Neonatal Diffusion Tensor Imaging and Neurodevelopmental Outcomes Following Term Neonatal Asphyxia and Therapeutic Hypothermia: An Exploratory Pilot Study

2019 ◽  
Vol 34 (10) ◽  
pp. 556-566 ◽  
Author(s):  
Gwendolyn J. Gerner ◽  
Eric I. Newman ◽  
V. Joanna Burton ◽  
Brenton Roman ◽  
Elizabeth A. Cristofalo ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Pilot Study ◽  
Therapeutic Hypothermia ◽  
Diffusion Tensor ◽  
White Matter Injury ◽  
Hypoxic Ischemic Encephalopathy ◽  
Group Differences ◽  
Neurodevelopmental Outcomes ◽  
Ischemic Encephalopathy

Aim: Hypoxic-ischemic encephalopathy is associated with damage to deep gray matter; however, white matter involvement has become recognized. This study explored differences between patients and clinical controls on diffusion tensor imaging, and relationships between diffusion tensor imaging and neurodevelopmental outcomes. Method: Diffusion tensor imaging was obtained for 31 neonates after hypoxic-ischemic encephalopathy treated with therapeutic hypothermia and 10 clinical controls. A subgroup of patients with hypoxic-ischemic encephalopathy (n = 14) had neurodevelopmental outcomes correlated with diffusion tensor imaging scalars. Results: Group differences in diffusion tensor imaging scalars were observed in the putamen, anterior and posterior centrum semiovale, and the splenium of the corpus callosum. Differences in these regions of interest were correlated with neurodevelopmental outcomes between ages 20 and 32 months. Conclusion: Therapeutic hypothermia may not be a complete intervention for hypoxic-ischemic encephalopathy, as neonatal white matter changes may continue to be evident, but further research is warranted. Patterns of white matter change on neonatal diffusion tensor imaging correlated with neurodevelopmental outcomes in this exploratory pilot study.

scholarly journals Diffusion Tensor Imaging on Teenagers, Born at Term With Moderate Hypoxic-ischemic Encephalopathy

2005 ◽  
Vol 58 (5) ◽  
pp. 936-940 ◽  
Author(s):  
Zoltan Nagy ◽  
Katarina Lindström ◽  
Helena Westerberg ◽  
Stefan Skare ◽  
Jesper Andersson ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy
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