scholarly journals Functional outcome of very preterm–born and small-for-gestational-age children at school age

2012 ◽  
Vol 72 (6) ◽  
pp. 641-648 ◽  
Author(s):  
Jozien C. Tanis ◽  
Meike H. van der Ree ◽  
Elise Roze ◽  
Anna E. Huis in ‘t Veld ◽  
Paul P. van den Berg ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183519 ◽  
Author(s):  
Sakari Lemola ◽  
Nadine Oser ◽  
Natalie Urfer-Maurer ◽  
Serge Brand ◽  
Edith Holsboer-Trachsler ◽  
...  

2012 ◽  
Vol 40 (S1) ◽  
pp. 34-34
Author(s):  
J. C. Tanis ◽  
K. N. Van Braeckel ◽  
J. M. Kerstjens ◽  
I. F. Bocca-Tjeertes ◽  
S. A. Reijneveld ◽  
...  

2008 ◽  
Vol 23 (8) ◽  
pp. 1309-1315 ◽  
Author(s):  
Alexander Rakow ◽  
Stefan Johansson ◽  
Lena Legnevall ◽  
Robin Sevastik ◽  
Gianni Celsi ◽  
...  

Neonatology ◽  
2013 ◽  
Vol 103 (4) ◽  
pp. 293-299 ◽  
Author(s):  
Inger F.A. Bocca-Tjeertes ◽  
Sijmen A. Reijneveld ◽  
Jorien M. Kerstjens ◽  
Andrea F. de Winter ◽  
Arend F. Bos

1990 ◽  
Vol 23 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Henk Wierenga ◽  
Ronald Brand ◽  
Theo Geudeke ◽  
Herman P. van Geijn ◽  
Hans van der Harten ◽  
...  

2018 ◽  
Vol 104 (2) ◽  
pp. F192-F198 ◽  
Author(s):  
Erik A Jensen ◽  
Elizabeth E Foglia ◽  
Kevin C Dysart ◽  
Rebecca A Simmons ◽  
Zubair H Aghai ◽  
...  

ObjectiveTo characterise the excess risk for death, grade 3–4 intraventricular haemorrhage (IVH), bronchopulmonary dysplasia (BPD) and stage 3–5 retinopathy of prematurity independently associated with birth small for gestational age (SGA) among very preterm infants, stratified by completed weeks of gestation.MethodsRetrospective cohort study using the Optum Neonatal Database. Study infants were born <32 weeks gestation without severe congenital anomalies. SGA was defined as a birth weight <10th percentile. The excess outcome risk independently associated with SGA birth among SGA babies was assessed using adjusted risk differences (aRDs).ResultsOf 6708 infants sampled from 717 US hospitals, 743 (11.1%) were SGA. SGA compared with non-SGA infants experienced higher unadjusted rates of each study outcome except grade 3–4 IVH among survivors. The excess risk independently associated with SGA birth varied by outcome and gestational age. The highest aRD for death (0.27; 95% CI 0.13 to 0.40) occurred among infants born at 24 weeks gestation and declined as gestational age increased. In contrast, the peak aRDs for BPD among survivors (0.32; 95% CI 0.20 to 0.44) and the composites of death or BPD (0.35; 95% CI 0.24 to 0.46) and death or major morbidity (0.35; 95% CI 0.24 to 0.45) occurred at 27 weeks gestation. The risk-adjusted probability of dying or developing one or more of the evaluated morbidities among SGA infants was similar to that of non-SGA infants born approximately 2–3 weeks less mature.ConclusionThe excess risk for neonatal morbidity and mortality associated with being born SGA varies by adverse outcome and gestational age.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Preethi Mathew ◽  
Kerstin Pannek ◽  
Pamela Snow ◽  
M. Giulia D'Acunto ◽  
Andrea Guzzetta ◽  
...  

Background. The etiology of motor impairments in preterm infants is multifactorial and incompletely understood. Whether corpus callosum development is related to impaired motor function is unclear. Potential associations between motor-related measures and diffusion tensor imaging (DTI) of the corpus callosum in preterm infants were explored.Methods. Eight very preterm infants (gestational age of 28–32 weeks) underwent the Hammersmith neonatal neurological examination and DTI assessments at gestational age of 42 weeks. The total Hammersmith score and a motor-specific score (sum of Hammersmith motor subcategories) were calculated. Six corpus callosum regions of interest were defined on the mid-sagittal DTI slice—genu, rostral body, anterior midbody, posterior midbody, isthmus, and splenium. The fractional anisotropy (FA) and mean diffusivity (MD) of these regions were computed, and correlations between these and Hammersmith measures were sought.Results. Anterior midbody FA measures correlated positively with total Hammersmith (rho=0.929,P=0.001) and motor-specific scores (rho=0.857,P=0.007). Total Hammersmith scores also negatively correlated with anterior midbody MD measures (rho=−0.714,P=0.047).Discussion. These results suggest the integrity of corpus callosum axons, particularly anterior midbody axons, is important in mediating neurological functions. Greater callosal maturation was associated with greater motor function. Corpus callosum DTI may prove to be a valuable screening or prognostic marker.


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