scholarly journals Volume Changes of Whole Brain Gray and White Matter in Children Patients with Tourette's Syndrome: Evidence from Voxel-Based Morphometry

2011 ◽  
Vol 70 ◽  
pp. 187-187 ◽  
Author(s):  
Y Liu ◽  
Y Peng ◽  
P Gao ◽  
B Nie
2008 ◽  
Vol 65 (1) ◽  
pp. 86-90 ◽  
Author(s):  
Aihong Yu ◽  
Kuncheng Li ◽  
Lin Li ◽  
Baoci Shan ◽  
Yuping Wang ◽  
...  

2010 ◽  
Vol 20 ◽  
pp. S303-S304
Author(s):  
T. Sobanski ◽  
G. Wagner ◽  
G. Peikert ◽  
U. Gruhn ◽  
H. Sauer ◽  
...  

2008 ◽  
Vol 6 (4) ◽  
pp. 147470490800600 ◽  
Author(s):  
Matthew Euler ◽  
Robert J. Thoma ◽  
Lauren Parks ◽  
Steven W. Gangestad ◽  
Ronald A. Yeo

Composite measures of fluctuating asymmetry (FA) of skeletal features are commonly used to estimate developmental instability (DI), the imprecise expression of developmental design due to perturbations during an individual's growth and maturation. Though many studies have detailed important behavioral correlates of FA, very little is known about its possible neuroanatomical correlates. In this study we obtained structural brain MRI scans from 20 adults and utilized voxel-based morphometry (VBM) to identify specific regions linked to FA. Greater FA predicted greater whole brain white matter volume, and a trend in the same direction was noted for whole brain gray matter volume. Greater FA was associated with significantly greater gray and white matter volumes in discrete brain regions, most prominently in the frontal lobes and in the right cerebral hemisphere. Developmental studies are needed to identify when FA-related brain differences emerge and to elucidate the specific neurobiological mechanisms leading to these differences.


2019 ◽  
Vol 61 (3) ◽  
pp. 395-403
Author(s):  
Biao Li ◽  
Yu-Xin Liu ◽  
Hai-Jun Li ◽  
Qing Yuan ◽  
Pei-Wen Zhu ◽  
...  

Background We know little about the pathogenesis and diagnosis of retinal detachment. Purpose To assess spontaneous changes in the cerebral cortex of patients with retinal detachment using voxel-based morphometry and to explore the relationship between retinal detachment and clinical behavioral performance. Material and Methods Patients (14 men, 6 women; average age = 49.15 ± 10.32 years) with rhegmatogenous retinal detachment (duration of 24.05 ± 19.61 days) and 20 matched healthy controls were recruited. All participants underwent repeated functional magnetic resonance imaging scans. The original three-dimensional T1 brain images were analyzed using voxel-based morphometry and whole brain white matter volume and whole brain gray matter volume were compared with those of the control group. A receiver operating characteristic (ROC) curve was used to classify the mean gray matter volume values of the patients with retinal detachment compared with the controls. Results Compared with the controls, whole brain gray matter volume was significantly reduced in patients with retinal detachment, as evidenced by changes in the right inferior frontal gyrus, right superior temporal gyrus, right anterior cingulate gyrus, and right cuneus. In addition, the posterior lobe of the cerebellum, left hippocampus, left cingulate gyrus, and left middle temporal gyrus were also obviously atrophied. Furthermore, whole brain white matter volume of the patients with retinal detachment showed a slight reduction. The ROC curve analysis of each brain region showed that the accuracy of the area under the curve was high. Conclusion We proved that patients with retinal detachment had unusual changes in the gray matter volume and white matter volume in vision-related brain regions, which could reveal potential pathological mechanisms of retinal detachment.


2006 ◽  
Vol 59 (5) ◽  
pp. 872-873 ◽  
Author(s):  
Jan Kassubek ◽  
Freimut D. Juengling ◽  
Andrea G. Ludolph

Sign in / Sign up

Export Citation Format

Share Document