scholarly journals Diffusion Tensor Imaging of the Internal Capsule and Corpus Callosum of Preterm Infants Born Under 28 Weeks Gestation

2011 ◽  
Vol 70 ◽  
pp. 149-149 ◽  
Author(s):  
J J Atkinson ◽  
L M Parkes ◽  
C Gamble ◽  
S M Ng ◽  
M Turner ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Corpus Callosum ◽  
Preterm Infants ◽  
Diffusion Tensor ◽  
Internal Capsule

scholarly journals Development of Corpus Callosum in Preterm Infants Is Affected by the Prematurity: In Vivo Assessment of Diffusion Tensor Imaging at Term-Equivalent Age

2011 ◽  
Vol 69 (3) ◽  
pp. 249-254 ◽  
Author(s):  
Tatsuji Hasegawa ◽  
Kei Yamada ◽  
Masafumi Morimoto ◽  
Shigemi Morioka ◽  
Takenori Tozawa ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Corpus Callosum ◽  
Preterm Infants ◽  
Diffusion Tensor ◽  
Equivalent Age ◽  
In Vivo Assessment

Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: A diffusion tensor imaging survey

2007 ◽  
Vol 92 (1-3) ◽  
pp. 211-224 ◽  
Author(s):  
Serge A. Mitelman ◽  
Yuliya Torosjan ◽  
Randall E. Newmark ◽  
Jason S. Schneiderman ◽  
King-Wai Chu ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Internal Capsule ◽  
Poor Outcome

Diffusion tensor imaging in hyperthyroidism: assessment of microstructural white matter abnormality with a tract-based spatial statistical analysis

2020 ◽  
Vol 61 (12) ◽  
pp. 1677-1683 ◽  
Author(s):  
Kerim Aslan ◽  
Hediye Pinar Gunbey ◽  
Sumeyra Cortcu ◽  
Onur Ozyurt ◽  
Ugur Avci ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corpus Callosum ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Imaging Study ◽  
Internal Capsule ◽  
Control Group ◽  
Corona Radiata ◽  
Microstructural Alterations

Background Metabolic, morphological, and functional brain changes associated with a neurological deficit in hyperthyroidism have been observed. However, changes in microstructural white matter (WM), which can explain the underlying pathophysiology of brain dysfunctions, have not been researched. Purpose To assess microstructural WM abnormality in patients with untreated or newly diagnosed hyperthyroidism using tract-based spatial statistics (TBSS). Material and Methods Eighteen patients with hyperthyroidism and 14 age- and sex-matched healthy controls were included in this study. TBSS were used in this diffusion tensor imaging study for a whole-brain voxel-wise analysis of fractional anisotropy, mean diffusivity, axial diffusivity (AD), and radial diffusivity (RD) of WM. Results When compared to the control group, TBSS showed a significant increase in the RD of the corpus callosum, anterior and posterior corona radiata, posterior thalamic radiation, cingulum, superior longitudinal fasciculus, and the retrolenticular region of the internal capsule in patients with hyperthyroidism ( P < 0.05), as well as a significant decrease in AD in the anterior corona radiata and the genu of corpus callosum ( P < 0.05). Conclusion This study showed that more regions are affected by the RD increase than the AD decrease in the WM tracts of patients with hyperthyroidism. These preliminary results suggest that demyelination is the main mechanism of microstructural alterations in the WM of hyperthyroid patients.

P02 - 361 White matter microstructural abnormalities in antisocial personality disorder: A pilot diffusion tensor imaging study

2011 ◽  
Vol 26 (S2) ◽  
pp. 957-957
Author(s):  
F. Sundram ◽  
Q. Deeley ◽  
S. Sarkar ◽  
E. Daly ◽  
R. Latham ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Personality Disorder ◽  
Corpus Callosum ◽  
Antisocial Personality Disorder ◽  
Diffusion Tensor ◽  
Internal Capsule ◽  
Uncinate Fasciculus ◽  
Antisocial Personality ◽  
The Right

IntroductionAntisocial personality disorder (ASPD) and psychopathy involve significant interpersonal and behavioural impairments. However, little is known about white matter (WM) abnormalities in tracts linking grey matter regions. A previous diffusion tensor imaging (DT-MRI) tractography study in ASPD and psychopathy revealed abnormalities in the right uncinate fasciculus, indicating fronto-limbic disconnectivity.ObjectivesIt is not clear whether WM abnormalities are restricted to only this tract or are more widespread. Therefore, we planned to use whole brain DT-MRI voxel-based analyses.AimsTo clarify if WM abnormalities extend beyond the frontal lobe.MethodsWe used whole brain DT-MRI to compare WM fractional anisotropy (FA) of 15 adults with ASPD and healthy age, handedness and IQ-matched controls. Also, within ASPD subjects, we related differences in FA to severity of psychopathy measures.ResultsSignificant WM FA reductions were found in ASPD subjects relative to controls. These were found bilaterally in the anterior corpus callosum. Right hemisphere FA reduction was found in the anterior corona radiata, uncinate fasciculus, inferior fronto-occipital fasciculus and internal capsule. Left hemisphere, FA deficits encompassed the inferior longitudinal fasciculus, inferior fronto-occipital fasciculus and internal capsule. There was a significant negative correlation between WM FA in the right uncinate fasciculus and corpus callosum and measures of psychopathy.ConclusionsWe report FA reduction in the uncinate fasciculus and anterior corpus callosum which may be associated with frontal and inter-hemispheric disconnectivity in ASPD, in addition to abnormalities in other tracts which directly or indirectly connect to prefrontal regions.

scholarly journals Diagnostic Value of Diffusion Tensor Imaging for Infants’ Brain Development Retardation Caused by Pre-Eclampsia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Qing-Na Xing ◽  
Yan-Chao Liu ◽  
De-Sheng Xuan ◽  
Hong-Lei Shang ◽  
Xin Zhao ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Brain Development ◽  
Preterm Infants ◽  
Diffusion Tensor ◽  
Internal Capsule ◽  
Diagnostic Value ◽  
Control Group ◽  
Positive Correlation ◽  
Brain White Matter ◽  
Medium Intensity

Objective. Pre-eclampsia (PE) can cause brain development delay in infants. This work aims to characterize the pattern differences of brain white matter development in premature infants under PE conditions and those without. Methods. Eighty preterm infants delivered by women with PE were selected as the PE group, and ninety-six preterm infants of the same period born to women without high-risk perinatal factors were used as control. All infants underwent diffusion tensor imaging (DTI) examination. The fractional anisotropy (FA) was measured in five regions of interests (ROIs), including posterior limbs of internal capsule (PLIC), splenium of the corpus callosum (SCC), superior frontal gyrus (SFG), superior parietal lobule (SPL), and superior occipital gyrus (SOG). The relationship between the FA values and postmenstrual age (PMA) was analyzed. Results. After adjusting for the birth weight and gestational ages, in the SCC and PLIC, the PMA and FA values showed a low-to-medium intensity positive correlation in the control group (r = 0.30, p = 0.003 ; r = 0.53, p < 0.0001 ), while no positive relevance was detected in the PE group (r = 0.08, p = 0.47 ; r = 0.19, p < 0.08 ). In the PE and control groups, in the SPL and SOG, the PMA and FA values showed a near-consistent positive correlation (r = 0.57, r = 0.55 vs. r = 0.31, r = 0.55; all p < 0.05 ). In the control group, in SFG, the PMA and FA values had a medium intensity positive correlation (r = 0.47, p < 0.0001 ), but there was no statistical difference in correlation in PE (r = 0.10, p = 0.39 ). Conclusion. PE may cause lagging brain development in the SCC, PLIC, and SFG during infancy. DTI may be an effective and sensitive detection tool.

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