Adaptation and external validation of the European randomised study of screening for prostate cancer risk calculator for the Chinese population

2016 ◽  
Vol 20 (1) ◽  
pp. 99-104 ◽  
Author(s):  
P K Chiu ◽  
M J Roobol ◽  
D Nieboer ◽  
J Y Teoh ◽  
S K Yuen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
External Validation ◽  
Prostate Cancer Risk ◽  
Risk Calculator ◽  
Randomised Study

European Randomized Study of Screening for Prostate Cancer Risk Calculator: External Validation, Variability, and Clinical Significance

Urology ◽  
2017 ◽  
Vol 102 ◽  
pp. 85-91 ◽  
Author(s):  
Enrique Gómez-Gómez ◽  
Julia Carrasco-Valiente ◽  
Ana Blanca-Pedregosa ◽  
Beatriz Barco-Sánchez ◽  
Jose Luis Fernandez-Rueda ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Clinical Significance ◽  
Randomized Study ◽  
External Validation ◽  
Prostate Cancer Risk ◽  
Risk Calculator

1874: External Validation of the Prostate Cancer Risk Calculator

2007 ◽  
Vol 177 (4S) ◽  
pp. 622-622 ◽  
Author(s):  
David J. Hernandez ◽  
Misop Han ◽  
Elizabeth B. Humphreys ◽  
Leslie A. Mangold ◽  
Michael K. Brawer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
External Validation ◽  
Prostate Cancer Risk ◽  
Risk Calculator

scholarly journals Next-generation prostate cancer risk calculator for primary care physicians

2017 ◽  
Vol 12 (2) ◽  
pp. E64-70 ◽  
Author(s):  
Robert K. Nam ◽  
Raj Satkunasivam ◽  
Joseph L. Chin ◽  
Jonathan Izawa ◽  
John Trachtenberg ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Life Expectancy ◽  
Prostate Biopsy ◽  
Primary Care Physicians ◽  
Prostate Cancer Risk ◽  
Concordance Index ◽  
Risk Calculator ◽  
Next Generation ◽  
Term Survival

Introduction: Current prostate cancer risk calculators are limited in impact because only a probability of having prostate cancer is provided. We developed the next generation of prostate cancer risk calculator that incorporates life expectancy in order to better evaluate prostate cancer risk in context to a patient’s age and comorbidity.Methods: We combined two cohorts to develop the new risk calculator. The first was 5638 subjects who all underwent a prostate biopsy for prostate cancer detection. The second was 979 men diagnosed with prostate cancer with long-term survival data. Two regression models were used to create multivariable nomograms and an online prostate cancer risk calculator was developed.Results: Of the 5638 patients who underwent a prostate biopsy, 629 (11%) were diagnosed with aggressive prostate cancer (Gleason Score 7[4+3] or more). Of the 979 patients who underwent treatment for prostate cancer, the 10-year overall survival (OS) was 49.6% (95% confidence interval [CI] 46.6‒52.9). The first multivariable nomogram for cancer risk had a concordance index of 0.74 (95% CI 0.72, 0.76), and the second nomogram to predict survival had a concordance index of 0.71 (95% CI 0.69‒0.72). The nextgeneration prostate cancer risk calculator was developed online and is available at: http://riskcalc.org/ProstateCA_Screen_Tool.Conclusions: We have developed the next-generation prostate cancer risk calculator that incorporates a patient’s life expectancy based on age and comorbidity. This approach will better evaluate prostate cancer risk. Future studies examining other populations will be needed for validation.

PROSTATE BIOPSY OUTCOME PREDICTION – COMPARISON OF A NOVEL LOGISTIC REGRESSION-BASED MODEL, THE PROSTATE CANCER RISK CALCULATOR AND PSA ALONE

2008 ◽  
Vol 179 (4S) ◽  
pp. 640-641
Author(s):  
David J Hernandez ◽  
Misop Han ◽  
Elizabeth B Humphreys ◽  
Leslie A Mangold ◽  
Michael K Brawer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Logistic Regression ◽  
Cancer Risk ◽  
Prostate Biopsy ◽  
Outcome Prediction ◽  
Prostate Cancer Risk ◽  
Risk Calculator
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