scholarly journals The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action

Oncogene ◽  
2016 ◽  
Vol 35 (38) ◽  
pp. 5033-5042 ◽  
Author(s):  
A Griveau ◽  
G Devailly ◽  
L Eberst ◽  
N Navaratnam ◽  
B Le Calvé ◽  
...  
Keyword(s):  
Suppressive Action

scholarly journals Enzymatic Synthesis and Anti-Allergic Activities of Curcumin Oligosaccharides

2010 ◽  
Vol 3 ◽  
pp. BCI.S2768 ◽  
Author(s):  
Kei Shimoda ◽  
Hiroki Hamada
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Enzymatic Synthesis ◽  
Antibody Formation ◽  
Cyclodextrin Glucanotransferase ◽  
Enzymatic Method ◽  
Inhibitory Effects ◽  
Peritoneal Mast Cells ◽  
Rat Peritoneal Mast Cells ◽  
Suppressive Action

Curcumin 4‘- O-glucooligosaccharides were synthesized by a two step-enzymatic method using almond β-glucosidase and cyclodextrin glucanotransferase (CGTase). Curcumin was glucosylated to curcumin 4‘- O-β-D-glucopyranoside by almond β-glucosidase in 19% yield. Curcumin 4‘- O-β-D-glucopyranoside was converted into curcumin 4‘- O-β-glucooligosaccharides, i.e. 4‘- O-β-maltoside (51%) and 4‘- O-β-maltotrioside (25%), by further CGTase-catalyzed glycosylation. Curcumin 4‘- O-β-glycosides showed suppressive action on IgE antibody formation and inhibitory effects on histamine release from rat peritoneal mast cells.

scholarly journals EFFECT OF GLYCYRRHIZIN ON THE SUPPRESSIVE ACTION OF CORTISONE ON THE PITUITARY ADRENAL AXIS

1966 ◽  
Vol 13 (3) ◽  
pp. 234-244 ◽  
Author(s):  
AKIRA KUMAGAI ◽  
YOSHITSUGU ASANUMA ◽  
SABURO YANO ◽  
KAZUYUKI TAKEUCHI ◽  
YASUHIKO MORIMOTO ◽  
...  
Keyword(s):  
Adrenal Axis ◽  
Pituitary Adrenal Axis ◽  
Suppressive Action

Permissive effect of cytochalasin B on DNA synthesis in concanavalin-A-treated lymphocytes

1984 ◽  
Vol 66 (1) ◽  
pp. 155-166
Author(s):  
K.G. Sundqvist ◽  
L. Wanger ◽  
W. Ensgstom
Keyword(s):  
Dna Synthesis ◽  
Concanavalin A ◽  
Cytochalasin B ◽  
Human Lymphocytes ◽  
Initial Period ◽  
Culture Conditions ◽  
Plant Lectins ◽  
Conventional Culture ◽  
Per Se ◽  
Suppressive Action

Unfractionated or T-cell-enriched human lymphocytes can be stimulated to undergo DNA synthesis and mitosis by the addition of polyclonal cell activators such as the plant lectins phytohaemagglutinin and concanavalin A (ConA). Under conventional culture conditions stimulated cells cease proliferating only a few days after the first cells have initiated DNA synthesis. Cytochalasin B (CB), which is non-mitogenic per se, causes a prolongation of the period during which ConA stimulates DNA synthesis from normally 3–5 days to more than 3 weeks. The CB-induced prolongation of cell proliferation is clearly stage-specific in the sense that the CB effects are exerted after an initial period of 24 h and do not come into effect until 48 h after onset of ConA stimulation. In contrast, CB exerts a slight suppressive action on DNA synthesis between 24 h (when activated cells initiate DNA synthesis) and 48 h after onset of stimulation. These two separate effects of CB, i.e. augmentation of lymphocyte stimulation 48 h after stimulation, and suppression of stimulation before this point of time, are relatively independent of the concentration of CB.

Suppressive action of acth on growth hormone secretion in patients with infantile spasms

1985 ◽  
Vol 7 (6) ◽  
pp. 636-639 ◽  
Author(s):  
Tatsuro Izumi ◽  
Chizuko Imaizumi ◽  
Etsuko Ashida ◽  
Takako Ochiai ◽  
Pen-Jung Wang ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Infantile Spasms ◽  
Suppressive Action

Suppressive action of acetate on interleukin‐8 production via tubulin‐α acetylation

2014 ◽  
Vol 92 (7) ◽  
pp. 624-630 ◽  
Author(s):  
Kazuhiro Ishiguro ◽  
Takafumi Ando ◽  
Osamu Maeda ◽  
Osamu Watanabe ◽  
Hidemi Goto
Keyword(s):  
Interleukin 8 ◽  
Suppressive Action

Suppressive action of cobalt on exocytosis and respiratory burst in neutrophils

1989 ◽  
Vol 257 (5) ◽  
pp. C859-C864 ◽  
Author(s):  
J. G. Elferink ◽  
M. Deierkauf
Keyword(s):  
Plasma Membrane ◽  
Phorbol Myristate Acetate ◽  
Respiratory Burst ◽  
Cytochalasin B ◽  
Superoxide Production ◽  
Co2 Activation ◽  
Chemotactic Peptide ◽  
Myristate Acetate ◽  
Intracellular Target ◽  
Suppressive Action

Activation of exocytosis and respiratory burst in rabbit neutrophils by the chemotactic peptide fMet-Leu-Phe is inhibited by Co2+. Inhibition is antagonized by extracellular Ca2+ and is dependent on the time of preincubation of cells with Co2+ before addition of activator. Co2+ inhibits the enhancement of 45Ca association that occurs during activation with fMet-Leu-Phe. Interference with Ca2+ translocation across the plasma membrane by Co2+ is probably not the cause of inhibition of neutrophil activation, because activation in the absence of extracellular Ca2+ is inhibited by Co2+. Activation of neutrophils by phorbol myristate acetate is inhibited at higher Co2+ concentrations than activation by fMet-Leu-Phe. Inhibition of the superoxide production by Co2+ occurs both in the presence or in the absence of cytochalasin B. Fluorescence of neutrophils loaded with quin2 is diminished by Co2+, indicating that Co2+ had entered into the cytoplasm. The results are compatible with the view that Co2+ inhibits exocytosis and respiratory burst in neutrophils by an interaction with a Ca2+-dependent intracellular target.

Lyophilized whole human melanoma cells enhanced suppressive action of PBMC toward survival of the corresponding malignant cell line in vitro

1999 ◽  
Vol 35 ◽  
pp. S358-S359
Author(s):  
Z.D. Juranic ◽  
T. Stanojkovic ◽  
N. Stanojevic-Bakic ◽  
D. Milosevic ◽  
S. Radulovic ◽  
...  
Keyword(s):  
Cell Line ◽  
Malignant Cell ◽  
Melanoma Cells ◽  
Human Melanoma ◽  
Malignant Cell Line ◽  
Human Melanoma Cells ◽  
Suppressive Action

Maternal behavior in male rats: Critical times for the suppressive action of androgens

1976 ◽  
Vol 16 (3) ◽  
pp. 293-297 ◽  
Author(s):  
Phyllis A. Rosenberg ◽  
Lorraine Roth Herrenkohl
Keyword(s):  
Maternal Behavior ◽  
Male Rats ◽  
Suppressive Action ◽  
Critical Times
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