scholarly journals Role of Runx2 in IGF-1Rβ/Akt- and AMPK/Erk-dependent growth, survival and sensitivity towards metformin in breast cancer bone metastasis

Oncogene ◽  
2016 ◽  
Vol 35 (36) ◽  
pp. 4730-4740 ◽  
Author(s):  
M Tandon ◽  
Z Chen ◽  
A H Othman ◽  
J Pratap
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Dependent Growth ◽  
Breast Cancer Bone Metastasis

Role of RAMP2 and BSP2 in the c-Src-regulated osteomimicry of breast cancer bone metastasis

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S273
Author(s):  
B. Peruzzi⁎ ◽  
M. Capulli ◽  
A. Teti ◽  
N. Rucci
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Breast Cancer Bone Metastasis

scholarly journals The role of katanin p60 in breast cancer bone metastasis

2018 ◽  
Author(s):  
Wenrong Fu ◽  
Hui Wu ◽  
Zhengjiang Cheng ◽  
Shaojun Huang ◽  
Hui Rao
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Breast Cancer Bone Metastasis

scholarly journals The Role of Adipokines and Bone Marrow Adipocytes in Breast Cancer Bone Metastasis

2020 ◽  
Vol 21 (14) ◽  
pp. 4967 ◽  
Author(s):  
Eunah Shin ◽  
Ja Seung Koo
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Bone Metastasis ◽  
Cancer Progression ◽  
Breast Cancer Cells ◽  
Cell Types ◽  
Bone Marrow Adipocytes ◽  
Bone Marrow Adipocyte ◽  
Breast Cancer Bone Metastasis

The morbidity and mortality of breast cancer is mostly due to a distant metastasis, especially to the bone. Many factors may be responsible for bone metastasis in breast cancer, but interactions between tumor cells and other surrounding types of cells, and cytokines secreted by both, are expected to play the most important role. Bone marrow adipocyte (BMA) is one of the cell types comprising the bone, and adipokine is one of the cytokines secreted by both breast cancer cells and BMAs. These BMAs and adipokines are known to be responsible for cancer progression, and this review is focused on how BMAs and adipokines work in the process of breast cancer bone metastasis. Their potential as suppressive targets for bone metastasis is also explored in this review.

scholarly journals The role of osteoclasts in breast cancer bone metastasis

2016 ◽  
Vol 5 (3) ◽  
pp. 93-95 ◽  
Author(s):  
François Le Pape ◽  
Geoffrey Vargas ◽  
Philippe Clézardin
Keyword(s):  
Breast Cancer ◽  
Bone Metastasis ◽  
Breast Cancer Bone Metastasis
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