scholarly journals Myocyte enhancer factor 2C in hematopoiesis and leukemia

Oncogene ◽  
2013 ◽  
Vol 33 (4) ◽  
pp. 403-410 ◽  
Author(s):  
K Canté-Barrett ◽  
R Pieters ◽  
J P P Meijerink
Keyword(s):  
Myocyte Enhancer Factor ◽  
Enhancer Factor

scholarly journals Involvement of myocyte enhancer factor 2c in the pathogenesis of autism spectrum disorder

Heliyon ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e06854
Author(s):  
Rishabh Chaudhary ◽  
Vipul Agarwal ◽  
Arjun Singh Kaushik ◽  
Mujeeba Rehman
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Myocyte Enhancer Factor ◽  
Enhancer Factor

Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2

2004 ◽  
Vol 127 (4) ◽  
pp. 1174-1188 ◽  
Author(s):  
Xuemin Wang ◽  
Xiaoli Tang ◽  
Xiaoming Gong ◽  
Efsevia Albanis ◽  
Scott L. Friedman ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Hepatic Stellate Cell ◽  
Cell Activation ◽  
Stellate Cell ◽  
Myocyte Enhancer Factor 2 ◽  
Hepatic Stellate Cell Activation ◽  
Myocyte Enhancer Factor ◽  
Enhancer Factor

scholarly journals Angiopoietin-1 Induces Krüppel-like Factor 2 Expression through a Phosphoinositide 3-Kinase/AKT-dependent Activation of Myocyte Enhancer Factor 2

2008 ◽  
Vol 284 (9) ◽  
pp. 5592-5601 ◽  
Author(s):  
Keisuke Sako ◽  
Shigetomo Fukuhara ◽  
Takashi Minami ◽  
Takao Hamakubo ◽  
Haihua Song ◽  
...  
Keyword(s):  
Myocyte Enhancer Factor 2 ◽  
Myocyte Enhancer Factor ◽  
Phosphoinositide 3 Kinase ◽  
Angiopoietin 1 ◽  
Enhancer Factor

scholarly journals Myocyte Enhancer Factor 2C and Nkx2–5 Up-regulate Each Other’s Expression and Initiate Cardiomyogenesis in P19 Cells

1998 ◽  
Vol 273 (52) ◽  
pp. 34904-34910 ◽  
Author(s):  
Ilona S. Skerjanc ◽  
Helen Petropoulos ◽  
Alan G. Ridgeway ◽  
Sharon Wilton
Keyword(s):  
P19 Cells ◽  
Myocyte Enhancer Factor ◽  
Enhancer Factor

scholarly journals A myocyte enhancer factor 2D (MEF2D) kinase activated during neuronal apoptosis is a novel target inhibited by lithium

2003 ◽  
Vol 86 (4) ◽  
pp. 1055-1055
Author(s):  
Daniel A. Linseman ◽  
Brandon J. Cornejo ◽  
Shoshona S. Le ◽  
Mary Kay Meintzer ◽  
Tracey A. Laessig ◽  
...  
Keyword(s):  
Neuronal Apoptosis ◽  
Myocyte Enhancer Factor ◽  
Novel Target ◽  
Enhancer Factor

scholarly journals Nemo-Like Kinase-Myocyte Enhancer Factor 2A Signaling Regulates Anterior Formation in Xenopus Development

2007 ◽  
Vol 27 (21) ◽  
pp. 7623-7630 ◽  
Author(s):  
Kiyotoshi Satoh ◽  
Junji Ohnishi ◽  
Atsushi Sato ◽  
Michio Takeyama ◽  
Shun-ichiro Iemura ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Neural Development ◽  
Marker Genes ◽  
Neural Structure ◽  
Animal Pole ◽  
Endogenous Expression ◽  
Myocyte Enhancer Factor ◽  
Molecular Events ◽  
Bone Morphogenic Protein 4 ◽  
Enhancer Factor

ABSTRACT The development of anterior neural structure in Xenopus laevis requires the inhibition of bone morphogenic protein 4 and Wnt signaling. We previously reported that Nemo-like kinase (NLK) negatively regulates Wnt signaling via the phosphorylation of T-cell factor/lymphoid enhancer factor. However, the molecular events occurring downstream of NLK pathways in early neural development remain unclear. In the present study, we identified the transcription factor myocyte enhancer factor 2A (MEF2A) as a novel substrate for NLK. NLK regulates the function of Xenopus MEF2A (xMEF2A) via phosphorylation, and this modification can be inhibited by the depletion of endogenous NLK. In Xenopus embryos, the depletion of either NLK or MEF2A results in a severe defect in anterior development. The endogenous expression of anterior markers was blocked by the depletion of endogenous Xenopus NLK (xNLK) or xMEF2A but, notably, not by the depletion of other xMEF2 family proteins, xMEF2C and xMEF2D. Defects in head formation or the expression of the anterior marker genes caused by the depletion of endogenous xMEF2A could be eliminated by the expression of wild-type xMEF2A, but not xMEF2A containing mutated xNLK phosphorylation sites. Furthermore, the expression of xNLK-induced anterior markers was efficiently blocked by the depletion of endogenous xMEF2A in animal pole explants. These results show that NLK specifically regulates the MEF2A activity required for anterior formation in Xenopus development.

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