scholarly journals COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer

Oncogene ◽  
2013 ◽  
Vol 33 (26) ◽  
pp. 3432-3440 ◽  
Author(s):  
Y-H Wu ◽  
T-H Chang ◽  
Y-F Huang ◽  
H-D Huang ◽  
C-Y Chou
Keyword(s):  
Ovarian Cancer ◽  
Clinical Outcome ◽  
Tumor Progression ◽  
Poor Clinical Outcome

Claspin Overexpression Promotes Tumor Progression and Predicts Poor Clinical Outcome in Prostate Cancer

2021 ◽  
Vol 25 (2) ◽  
pp. 131-139 ◽  
Author(s):  
Chao Cai ◽  
Jiexin Luo ◽  
Qinwei Liu ◽  
Zezhen Liu ◽  
Yan Zhao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Clinical Outcome ◽  
Tumor Progression ◽  
Poor Clinical Outcome

Cytoplasmic expression of estrogen receptor beta (ERβ) predicts poor clinical outcome in advanced serous ovarian cancer

2011 ◽  
Vol 122 (3) ◽  
pp. 573-579 ◽  
Author(s):  
Ilaria De Stefano ◽  
Gian Franco Zannoni ◽  
Maria Grazia Prisco ◽  
Anna Fagotti ◽  
Lucia Tortorella ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Clinical Outcome ◽  
Estrogen Receptor Beta ◽  
Serous Ovarian Cancer ◽  
Poor Clinical Outcome ◽  
Cytoplasmic Expression ◽  
Receptor Beta

scholarly journals High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression

2017 ◽  
Vol 37 (5) ◽  
pp. 2955-2963 ◽  
Author(s):  
Mengsi Ye ◽  
Yun He ◽  
Hao Lin ◽  
Shouxing Yang ◽  
Yuhui Zhou ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Clinical Outcome ◽  
Tumor Progression ◽  
High Expression ◽  
Poor Clinical Outcome

scholarly journals Overexpression of Runt-Related Transcription Factor-2 Is Associated with Advanced Tumor Progression and Poor Prognosis in Epithelial Ovarian Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Weiping Li ◽  
Shujuan Xu ◽  
Shuang Lin ◽  
Wei Zhao
Keyword(s):  
Ovarian Cancer ◽  
Transcription Factor ◽  
Clinical Outcome ◽  
Epithelial Ovarian Cancer ◽  
Tumor Progression ◽  
Clinical Stage ◽  
Runx2 Expression ◽  
Advanced Tumor ◽  
Clinical Stages ◽  
Related Transcription Factor

Aim. To investigate clinical significance of runt-related transcription factor (RUNX)-2 in epithelial ovarian cancer (EOC).Methods. RUNX2 protein expression and its subcellular localization were detected by immunohistochemistry in 116 patients with EOC.Results. RUNX2 protein was predominantly expressed in cell nucleus of EOC tissues. The expression level of RUNX2 in EOC tissues was significantly higher than that in normal ovarian tissues(P<0.001). In addition, the nuclear labeling index (LI) of RUNX2 in tumor cells was significantly associated with the advanced clinical stage of EOC tissues(P=0.001). Moreover, EOC patients with high RUNX2 LI had significantly shorter overall(P<0.001)and progression-free(P=0.002)survival than those with low RUNX2 LI. Especially, subgroup analysis revealed that EOC patients with high clinical stages (III~IV) in high RUNX2 expression group demonstrated a significantly worse clinical outcome than those in low RUNX2 expression group, but patients with low clinical stages (I~II) had no significantly different prognosis between high and low RUNX2 expression groups.Conclusions. Our data suggest for the first time that RUNX2 overexpression is associated with advanced tumor progression and poor clinical outcome of EOC patients. RUNX2 might be a novel prognostic marker of EOC.

Abstract 1511: Stromal gene signature regulated by TGFβ signaling predicts poor clinical outcome in ovarian cancer .

2013 ◽  
Author(s):  
Dong-Joo Cheon ◽  
Yunguang Tong ◽  
Myung-Shin Sim ◽  
Xiaojiang Cui ◽  
Dror Berel ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Clinical Outcome ◽  
Gene Signature ◽  
Tgfβ Signaling ◽  
Poor Clinical Outcome

scholarly journals MEP1A contributes to tumor progression and predicts poor clinical outcome in human hepatocellular carcinoma

Hepatology ◽  
2016 ◽  
Vol 63 (4) ◽  
pp. 1227-1239 ◽  
Author(s):  
Han-Yue OuYang ◽  
Jing Xu ◽  
Jun Luo ◽  
Ru-Hai Zou ◽  
Keng Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Outcome ◽  
Tumor Progression ◽  
Human Hepatocellular Carcinoma ◽  
Poor Clinical Outcome

scholarly journals Class III β-Tubulin Overexpression Is a Marker of Poor Clinical Outcome in Advanced Ovarian Cancer Patients

2006 ◽  
Vol 12 (9) ◽  
pp. 2774-2779 ◽  
Author(s):  
Gabriella Ferrandina ◽  
Gian Franco Zannoni ◽  
Enrica Martinelli ◽  
Amelia Paglia ◽  
Valerio Gallotta ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Clinical Outcome ◽  
Cancer Patients ◽  
Advanced Ovarian Cancer ◽  
Class Iii ◽  
Poor Clinical Outcome ◽  
Β Tubulin
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