Association of LIPA Gene Polymorphisms With Obesity-Related Metabolic Complications Among Severely Obese Patients

Obesity ◽  
2012 ◽  
Vol 20 (10) ◽  
pp. 2075-2082 ◽  
Author(s):  
Frédéric Guénard ◽  
Alain Houde ◽  
Luigi Bouchard ◽  
André Tchernof ◽  
Yves Deshaies ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Obese Patients ◽  
Metabolic Complications ◽  
Severely Obese

scholarly journals DUSP1 gene polymorphisms are associated with obesityrelated metabolic complications and gene methylation levels in severely obese patients

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Frédéric Guénard ◽  
Luigi Bouchard ◽  
André Tchernof ◽  
Yves Deshaies ◽  
Frédéric‐Simon Hould ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Obese Patients ◽  
Gene Methylation ◽  
Metabolic Complications ◽  
Severely Obese

scholarly journals Impact of NMT1 Gene Polymorphisms on Features of the Metabolic Syndrome among Severely Obese Patients

2016 ◽  
Vol 2 (4) ◽  
pp. 101-110
Author(s):  
Stéphanie Bégin ◽  
◽  
Frédéric Guénard ◽  
André Tchernof ◽  
Yves Deshaies ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Gene Polymorphisms ◽  
Obese Patients ◽  
The Metabolic Syndrome ◽  
Severely Obese

scholarly journals DUSP1Gene Polymorphisms Are Associated with Obesity-Related Metabolic Complications among Severely Obese Patients and Impact on Gene Methylation and Expression

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
F. Guénard ◽  
L. Bouchard ◽  
A. Tchernof ◽  
Y. Deshaies ◽  
F. S. Hould ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Obese Patients ◽  
Gene Methylation ◽  
Metabolic Complications ◽  
Expression Levels ◽  
Cpg Sites ◽  
Severely Obese ◽  
The Impact ◽  
Gene Expression Levels

TheDUSP1gene encodes a member of the dual-specificity phosphatase family previously identified as being differentially expressed in visceral adipose tissue (VAT) of severely obese men with versus without the metabolic syndrome.Objective.To test the association betweenDUSP1polymorphisms, obesity-related metabolic complications, gene methylation, and expression levels in VAT.Methods.TheDUSP1locus and promoter region were sequenced in 25 individuals. SNPs were tested for association with obesity-related complications in a cohort of more than 1900 severely obese individuals. The impact of SNPs on methylation levels of 36 CpG sites and correlations between DNA methylation and gene expression levels in VAT were computed in a subset of 14 samples.Results.Heterozygotes for rs881150 had lower HDL-cholesterol levels (HDL-C;P=0.01), and homozygotes for the minor allele of rs13184134 and rs7702178 had increased fasting glucose levels (P=0.04and 0.01, resp.). rs881150 was associated with methylation levels of CpG sites located ~1250 bp upstream the transcription start site. Methylation levels of 4 CpG sites were inversely correlated withDUSP1gene expression.Conclusion.These results suggest thatDUSP1polymorphisms modulate plasma glucose and HDL-C levels in obese patients possibly through alterations of DNA methylation and gene expression levels.

2030-P: The Efficacy of Laparoscopic Sleeve Gastrectomy in Severely Obese Patients with Varying Serum Triglyceride Levels

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2030-P
Author(s):  
GUIFANG LI ◽  
YUEYE HUANG ◽  
JUNYI ZHANG ◽  
XINGCHUN WANG ◽  
CHUNHUA QIAN ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Serum Triglyceride ◽  
Obese Patients ◽  
Severely Obese

Differential impact of bariatric surgery-induced weight loss on upper leg tissue composition in severely obese patients

2011 ◽  
Vol 35 (2) ◽  
pp. 188
Author(s):  
A. Auclair ◽  
J. Martin ◽  
M. Bastien ◽  
N. Bonneville ◽  
S. Marceau ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Weight Loss ◽  
Obese Patients ◽  
Tissue Composition ◽  
Differential Impact ◽  
Severely Obese

scholarly journals Blood Pressure Measurement in Severely Obese Patients: Validation of the Forearm Approach in Different Arm Positions

2018 ◽  
Vol 32 (2) ◽  
pp. 175-185 ◽  
Author(s):  
Marie-Ève Leblanc ◽  
Audrey Auclair ◽  
Jacinthe Leclerc ◽  
Jean Bussières ◽  
Mohsen Agharazii ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement ◽  
Obese Patients ◽  
Severely Obese

Poor mental health in severely obese patients is not explained by the presence of comorbidities

2014 ◽  
Vol 5 (1) ◽  
pp. 12-21 ◽  
Author(s):  
R. Somerville ◽  
K. McKenzie ◽  
S. Eslami ◽  
C. Breen ◽  
D. O'Shea ◽  
...  
Keyword(s):  
Mental Health ◽  
Poor Mental Health ◽  
Obese Patients ◽  
Severely Obese

scholarly journals Ophthalmologic evaluation of severely obese patients undergoing bariatric surgery: A pilot, monocentric, prospective, open-label study

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216351 ◽  
Author(s):  
Chiara Posarelli ◽  
Guido Salvetti ◽  
Paolo Piaggi ◽  
Francesca Guido ◽  
Giovanni Ceccarini ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Obese Patients ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Severely Obese

Association between nesfatin-1 levels and metabolic improvements in severely obese patients who underwent biliopancreatic derivation with duodenal switch

Peptides ◽  
2016 ◽  
Vol 86 ◽  
pp. 6-12 ◽  
Author(s):  
David H. St-Pierre ◽  
Julie Martin ◽  
Hiroyuki Shimizu ◽  
Yuko Tagaya ◽  
Takahumi Tsuchiya ◽  
...  
Keyword(s):  
Duodenal Switch ◽  
Obese Patients ◽  
Severely Obese
Sign in / Sign up

Export Citation Format

Share Document