Retinol-binding Protein 4, Visceral Fat, and the Metabolic Syndrome: Effects of Weight Loss

Obesity ◽  
2008 ◽  
Vol 16 (11) ◽  
pp. 2439-2444 ◽  
Author(s):  
Alexander Tschoner ◽  
Wolfgang Sturm ◽  
Julia Engl ◽  
Susanne Kaser ◽  
Markus Laimer ◽  
...  
2009 ◽  
Vol 85 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Cheng-Chieh Lin ◽  
Ming-May Lai ◽  
Tsai-Chung Li ◽  
Chia-Ing Li ◽  
Chiu-Shong Liu ◽  
...  

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Aleksandra Klisic ◽  
Nebojsa Kavaric ◽  
Ivan Soldatovic ◽  
Ana Ninic ◽  
Jelena Kotur-Stevuljevic

Abstract Background Retinol-binding protein 4 (RBP4) and cystatin C are regarded as novel metabolic risk markers. Therefore, we aimed to examine which one of these biomarkers better correlates with metabolic syndrome (MetS) in a cohort of postmenopausal women. Methods A total of 129 postmenopausal women (among which 62 women had MetS) were recruited in this cross-sectional study. MetS was diagnosed according to the International Diabetes Federation criteria. Results Cystatin C and RBP4 levels were significantly higher in women with MetS, compared to those without MetS (p=0.011 vs. p<0.001, respectively). A significant difference in the proportion of women with and without MetS across cystatin C and RBP4 quartiles was observed (χ2=5.1, p=0.025, and χ2=11.1, p=0.001, respectively). Logistic regression analysis revealed a borderline significant relationship between cystatin C and MetS (p=0.066), but this significance disappeared after adjustment for age, inflammation level and duration of menopause (p=0.221). On the contrary, a significant relationship between RBP4 and MetS was observed not only without adjustment (p=0.009), but also even after adjustment for age, inflammation level and duration of menopause (p=0.006). Conclusions RBP4 better correlates with MetS than cystatin C in postmenopausal women.


Sign in / Sign up

Export Citation Format

Share Document