Myocardial Ischemic-reperfusion Injury in a Rat Model of Metabolic Syndrome

Obesity ◽  
2008 ◽  
Vol 16 (10) ◽  
pp. 2253-2258 ◽  
Author(s):  
Mahmood S. Mozaffari ◽  
Stephen W. Schaffer
Keyword(s):  
Metabolic Syndrome ◽  
Reperfusion Injury ◽  
Rat Model ◽  
Ischemic Reperfusion Injury ◽  
Ischemic Reperfusion

Propofol with N-Acetylcysteine Reduces Global Myocardial Ischemic Reperfusion Injury More than Ketamine in a Rat Model

2009 ◽  
Vol 22 (5) ◽  
pp. 348-352 ◽  
Author(s):  
Hafize Oksuz ◽  
Nimet Senoglu ◽  
Aptekin Yasim ◽  
Hasan Turut ◽  
Fatma Tolun ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Rat Model ◽  
Ischemic Reperfusion Injury ◽  
Ischemic Reperfusion

scholarly journals Inhibition of Hepatic Ischemic Reperfusion Injury Using Saline Exposed to Electron Discharge in a Rat Model

Cell Medicine ◽  
2013 ◽  
Vol 5 (2-3) ◽  
pp. 83-87 ◽  
Author(s):  
Masaharu Dozen ◽  
Shin Enosawa ◽  
Yuki Tada ◽  
Keisuke Hirasawa
Keyword(s):  
Reperfusion Injury ◽  
Rat Model ◽  
Ischemic Reperfusion Injury ◽  
Ischemic Reperfusion

scholarly journals PET Demonstrates Functional Recovery after Treatment by Danhong Injection in a Rat Model of Cerebral Ischemic-Reperfusion Injury

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Zefeng Wang ◽  
Fahuan Song ◽  
Jinhui Li ◽  
Yuyan Zhang ◽  
Yu He ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Reperfusion Injury ◽  
Rat Model ◽  
Infarct Volume ◽  
Cerebral Infarct ◽  
Ischemic Reperfusion Injury ◽  
Ischemic Reperfusion ◽  
Danhong Injection ◽  
Cerebral Ischemic ◽  
Cerebral Ischemic Reperfusion

This study aimed to investigate neuroprotection of Danhong injection (DHI) in a rat model of cerebral ischemia using18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET).Method. Rats were divided into 5 groups: sham group, ischemia-reperfusion untreated (IRU) group, DHI-1 group (DHI 1 mL/kg/d), DHI-2 group (DHI 2 mL/kg/d), and DHI-4 group (DHI 4 mL/kg/d). AII the treated groups were intraperitoneally injected with DHI daily for 14 days. The therapeutic effects in terms of cerebral infarct volume, neurological function, and cerebral glucose metabolism were evaluated. Expression of TNF-αand IL-1βwas detected with enzyme-linked immunosorbent assay (ELISA). Levels of mature neuronal marker (NeuN), glial marker (GFAP), vascular density factor (vWF), and glucose transporter 1 (GLUT1) were assessed by immunohistochemistry.Results. Compared with the IRU group, rats treated with DHI showed dose dependent reductions in cerebral infarct volume and levels of proinflammatory cytokines, improvement of neurological function, and recovery of cerebral glucose metabolism. Meanwhile, the significantly increased numbers of neurons, gliocytes, and vessels and the recovery of glucose utilization were found in the peri-infarct region after DHI treatment using immunohistochemical analysis.Conclusion. This study demonstrated the metabolic recovery after DHI treatment by micro-PET imaging with18F-FDG and the neuroprotective effects of DHI in a rat model of cerebral ischemic-reperfusion injury.

The Effect of C1 Esterase Inhibitor on Ischemic Reperfusion Injury in Rat Epigastric Skin Flaps: Preliminary Results

2014 ◽  
Vol 30 (S 01) ◽  
Author(s):  
Inmaculada Jurado ◽  
Alberto Rodríguez ◽  
Carmen Vázquez ◽  
Víctor Velasco ◽  
Víctor Turrión ◽  
...  
Keyword(s):  
Reperfusion Injury ◽  
Skin Flaps ◽  
Ischemic Reperfusion Injury ◽  
Preliminary Results ◽  
C1 Esterase Inhibitor ◽  
Ischemic Reperfusion ◽  
Esterase Inhibitor
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