Effect of Food Restriction on Ghrelin in Normal-Cycling Female Rats and in Pregnancy

2002 ◽  
Vol 10 (7) ◽  
pp. 682-687 ◽  
Author(s):  
Oreste Gualillo ◽  
Jorge E. Caminos ◽  
Rubén Nogueiras ◽  
Luisa M. Seoane ◽  
Eva Arvat ◽  
...  
Keyword(s):  
Food Restriction ◽  
Female Rats ◽  
Effect Of Food ◽  
In Pregnancy

Effect of food manipulation on the GnRH-LH-estradiol axis of young female rats

1988 ◽  
Vol 254 (4) ◽  
pp. R616-R621 ◽  
Author(s):  
F. H. Bronson
Keyword(s):  
Food Restriction ◽  
Dark Period ◽  
Pubertal Development ◽  
Young Female ◽  
Female Rats ◽  
The Third ◽  
Feedback Sensitivity ◽  
Effect Of Food ◽  
Ad Libitum ◽  
Ad Libitum Feeding

Female rats were prevented from growing and developing reproductively by restricting their food intake from the time they reached 80-85 g (27-29 days of age) until they were 2 mo old. A return to ad libitum feeding then typically yielded the pubertal ovulation during the third or fourth dark period. Ad libitum feeding for 48 h increased the frequency of luteinizing hormone (LH) pulsing in ovariectomized females. This treatment also depressed the level of circulating estradiol in ovariectomized females implanted with Silastic capsules. It had no effect on the rate at which estradiol was cleared from the blood in a 1-h test, however, nor did it affect the pool of assayable gonadotropin-releasing hormone (GnRH) in the hypothalamus, the pool of assayable LH in the pituitary, the response of the pituitary to GnRH, or the rate at which LH was cleared from the blood. In toto, the present results suggest that food restriction inhibits pubertal development by acting rather specifically on GnRH secretion via an ovarian steroid-independent pathway. The presumed supplemental role for enhanced negative-feedback sensitivity could not be evaluated because of the aberrant results with encapsulated estradiol.

Food restriction and reproductive development: male and female mice and male rats

1986 ◽  
Vol 250 (3) ◽  
pp. R370-R376 ◽  
Author(s):  
G. D. Hamilton ◽  
F. H. Bronson
Keyword(s):  
Food Restriction ◽  
Reproductive Development ◽  
Body Growth ◽  
Female Rats ◽  
Male Rats ◽  
Male And Female ◽  
Female Mice ◽  
Total Absence ◽  
Body Weights ◽  
Effect Of Food

The effect of food restriction on reproductive development was compared in male and female mice. This was accomplished using an experimental design that allowed us to assess the amount of reproductive development that could occur in the total absence of body growth, when growth was stopped at each of three different body weights. Our results demonstrate that reproductive development has much more inertia in males than in females. Specifically, the final stages of reproductive development can proceed largely independently of body growth in males but not in females. This same design was also employed in an abbreviated study of male rats. When its results are coupled with the existing literature for female rats, it appears as though the sex differences noted above are characteristic of both species.

The effect of level of milk intake and protein content in the post-weaning diet on internal fat distribution of lambs

1993 ◽  
Vol 1993 ◽  
pp. 123-123
Author(s):  
T. Manso ◽  
A.R. Mantecón ◽  
M.A. Chaso ◽  
P. Lavin ◽  
T. Castro
Keyword(s):  
Protein Content ◽  
Food Restriction ◽  
Fat Distribution ◽  
Milk Intake ◽  
Energy Reserves ◽  
Fat Depots ◽  
Effect Of Food

The effect of food restriction and subsequent realimentation depends on age of animals at restriction and energy/protein relationship during post-restriction period (Ryan, 1990). In Spanish Churra breed the internal fat depots are the most important energy reserves (Frutos et al., 1991) and the proportion of different depots after restriction could be affect to recovery during realimentation.The aim of this paper is to study the effect of level of intake during milk-fed period and the protein content in the diet during the post-weaning period on the performance and different internal fat depots in the Churra lambs until they were 20 Kg of live weigth (LW).

scholarly journals Gestation Food Restriction and Refeeding Compensate Maternal Energy Status and Alleviate Metabolic Consequences in Juvenile Offspring in a Rabbit Model

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 310
Author(s):  
Rosa M. García-García ◽  
María Arias-Álvarez ◽  
Pilar Millán ◽  
María Rodríguez ◽  
Ana Sánchez-Rodríguez ◽  
...  
Keyword(s):  
Food Restriction ◽  
Rabbit Model ◽  
Later Life ◽  
Female Offspring ◽  
Energy Status ◽  
Juvenile Period ◽  
Body Reserves ◽  
Effect Of Food ◽  
Serum Aminotransferases ◽  
Similar Body

Nutritional status during gestation can influence mother and offspring metabolism. Undernutrition in pregnancy affects women in both western and developing countries, and it is associated with a high prevalence of chronic diseases in later life. The present work was conducted in the rabbit model, as a longitudinal study, to examine the effect of food restriction during early and mid-gestation, and re-feeding ad libitum until the end of pregnancy on metabolic status and body reserves of mother and, its association with development and metabolism of fetuses and female offspring to the juvenile stage. Little changes in live body weight (LBW), compensatory feed intake, similar body reserves, and metabolism were observed in dams. Placenta biometry and efficiency were slightly affected, but fetal BW and phenotype were not modified. However, hyperinsulinemia, insulin resistance, and hypertriglyceridemia were demonstrated in pre-term fetuses. In the juvenile period, these changes were not evidenced, and a similar pattern of growth and serum metabolic parameters in offspring of food-restricted mothers were found, except in serum aminotransferases levels, which increased. These were associated with higher liver fibrosis. Maternal food restriction in the early and mid-pregnancy followed by re-feeding in our rabbit model established a compensatory energy status in dams and alleviated potential long-term consequences in growth and metabolism in the offspring, even if fetal metabolism was altered.

Food restriction-induced augmentation of heroin seeking in female rats: manipulations of ovarian hormones

2015 ◽  
Vol 232 (20) ◽  
pp. 3773-3782 ◽  
Author(s):  
Firas Sedki ◽  
James Gardner Gregory ◽  
Adriana Luminare ◽  
Tracey M. D’Cunha ◽  
Uri Shalev
Keyword(s):  
Food Restriction ◽  
Ovarian Hormones ◽  
Female Rats

Effect of food restriction on the insulin signalling pathway in rat skeletal muscle and adipose tissue

2005 ◽  
Vol 16 (10) ◽  
pp. 602-609 ◽  
Author(s):  
Ana Alonso ◽  
Yolanda Fernández ◽  
Rebeca Fernández ◽  
Patricia Ordóñez ◽  
María Moreno ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Adipose Tissue ◽  
Food Restriction ◽  
Insulin Signalling ◽  
Signalling Pathway ◽  
Rat Skeletal Muscle ◽  
Insulin Signalling Pathway ◽  
Effect Of Food

Maternal food restriction in rats of the F0 generation increases retroperitoneal fat, the number and size of adipocytes and induces periventricular astrogliosis in female F1 and male F2 generations

2017 ◽  
Vol 29 (7) ◽  
pp. 1340 ◽  
Author(s):  
A. O. Joaquim ◽  
C. P. Coelho ◽  
P. Dias Motta ◽  
L. F. Felício ◽  
E. F. Bondan ◽  
...  
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Food Restriction ◽  
Bodyweight Gain ◽  
Male Offspring ◽  
Acidic Protein ◽  
Female Rats ◽  
Juvenile Period ◽  
Gfap Expression ◽  
F2 Generation ◽  
F1 Generation

The present study investigated whether male offspring (F2 generation) from female rats (F1 generation) whose mothers (F0 generation) were food restricted during gestation inherit a phenotypic transgenerational tendency towards being overweight and obese in the juvenile period, in the absence of food restriction in the F1/F2 generations. Dams of the F0 generation were 40% food restricted during pregnancy. Bodyweight, the number and size of larger and small hypodermal adipocytes (HAs), total retroperitoneal fat (RPF) weight and the expression of glial fibrillary acidic protein (GFAP) in periventricular hypothalamic astrocytes (PHAs), as determined by immunohistochemistry, were evaluated in both generations. In the female F1 generation, there was low bodyweight gain only during the juvenile period (30–65 days of age), a decrease in the size of small adipocytes, an increase in the number of small adipocytes, an increase in RPF weight and an increase in GFAP expression in PHAs at 90–95 days of age. In males of the F2 generation at 50 days of age, there was increased bodyweight and RPF weight, and a small number of adipocytes and GFAP expression in PHAs. These data indicate that the phenotypic transgenerational tendency towards being overweight and obese was observed in females (F1) from mothers (F0) that were prenatally food restricted was transmitted to their male offspring.

Sign in / Sign up

Export Citation Format

Share Document