scholarly journals Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

2011 ◽  
Vol 18 (9) ◽  
pp. 1015-1019 ◽  
Author(s):  
Xuefeng Chen ◽  
Hengyao Niu ◽  
Woo-Hyun Chung ◽  
Zhu Zhu ◽  
Alma Papusha ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Regulation ◽  
Strand Break ◽  
Double Strand Break ◽  
Dna Double Strand Break ◽  
Cycle Regulation ◽  
End Resection

scholarly journals DNA double-strand break end resection: a critical relay point for determining the pathway of repair and signaling

2020 ◽  
Vol 1 (4) ◽  
pp. 155-171 ◽  
Author(s):  
Yoko Katsuki ◽  
Penny A. Jeggo ◽  
Yuki Uchihara ◽  
Minoru Takata ◽  
Atsushi Shibata
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Dna Double Strand Break ◽  
End Resection

scholarly journals Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

2012 ◽  
Vol 45 (4) ◽  
pp. 505-516 ◽  
Author(s):  
Sophie E. Polo ◽  
Andrew N. Blackford ◽  
J. Ross Chapman ◽  
Linda Baskcomb ◽  
Serge Gravel ◽  
...  
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Dna Double Strand Break ◽  
Dna End Resection ◽  
End Resection

scholarly journals The Effect of Atypical Nucleic Acids Structures in DNA Double Strand Break Repair: A Tale of R-loops and G-Quadruplexes

2021 ◽  
Vol 12 ◽  
Author(s):  
Rosa Camarillo ◽  
Sonia Jimeno ◽  
Pablo Huertas
Keyword(s):  
Nucleic Acids ◽  
Strand Break ◽  
Double Strand Break ◽  
Fine Tuning ◽  
Double Strand Break Repair ◽  
Dna Double Strand Breaks ◽  
Dna Double Strand Break ◽  
Break Repair ◽  
Dna End Resection ◽  
End Resection

The fine tuning of the DNA double strand break repair pathway choice relies on different regulatory layers that respond to environmental and local cues. Among them, the presence of non-canonical nucleic acids structures seems to create challenges for the repair of nearby DNA double strand breaks. In this review, we focus on the recently published effects of G-quadruplexes and R-loops on DNA end resection and homologous recombination. Finally, we hypothesized a connection between those two atypical DNA structures in inhibiting the DNA end resection step of HR.

Dependence of DNA double strand break repair pathways on cell cycle phase in human lymphoblastoid cells

2009 ◽  
Vol 50 (9) ◽  
pp. 815-822 ◽  
Author(s):  
Yoshio Takashima ◽  
Mayumi Sakuraba ◽  
Tomoko Koizumi ◽  
Hiroko Sakamoto ◽  
Makoto Hayashi ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Strand Break ◽  
Double Strand Break ◽  
Cell Cycle Phase ◽  
Double Strand Break Repair ◽  
Cycle Phase ◽  
Lymphoblastoid Cells ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair
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