scholarly journals The dynamics of the brain transcriptome revealed

2011 ◽  
Vol 12 (12) ◽  
pp. 703-703 ◽  
Author(s):  
Monica Hoyos Flight
Keyword(s):  
Brain Transcriptome ◽  
The Brain

scholarly journals A gene expression atlas for different kinds of stress in the mouse brain

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Tiziano Flati ◽  
Silvia Gioiosa ◽  
Giovanni Chillemi ◽  
Andrea Mele ◽  
Alberto Oliverio ◽  
...  
Keyword(s):  
Gene Expression ◽  
Coping With Stress ◽  
Gene Expression Atlas ◽  
Sequence Read Archive ◽  
Brain Transcriptome ◽  
Expression Atlas ◽  
Differential Gene ◽  
Stress Related Genes ◽  
Public Repositories ◽  
The Brain

AbstractStressful experiences are part of everyday life and animals have evolved physiological and behavioral responses aimed at coping with stress and maintaining homeostasis. However, repeated or intense stress can induce maladaptive reactions leading to behavioral disorders. Adaptations in the brain, mediated by changes in gene expression, have a crucial role in the stress response. Recent years have seen a tremendous increase in studies on the transcriptional effects of stress. The input raw data are freely available from public repositories and represent a wealth of information for further global and integrative retrospective analyses. We downloaded from the Sequence Read Archive 751 samples (SRA-experiments), from 18 independent BioProjects studying the effects of different stressors on the brain transcriptome in mice. We performed a massive bioinformatics re-analysis applying a single, standardized pipeline for computing differential gene expression. This data mining allowed the identification of novel candidate stress-related genes and specific signatures associated with different stress conditions. The large amount of computational results produced was systematized in the interactive “Stress Mice Portal”.

Accelerated aging of the brain transcriptome by the common chemotherapeutic doxorubicin

2021 ◽  
pp. 111451
Author(s):  
Alyssa N. Cavalier ◽  
Zachary S. Clayton ◽  
David A. Hutton ◽  
Devin Wahl ◽  
Julie A. Reisz ◽  
...  
Keyword(s):  
Accelerated Aging ◽  
Brain Transcriptome ◽  
The Common ◽  
The Brain

BINGE ALCOHOL CONSUMPTION IN ADOLESCENT AND ADULT MICE DIFFERENTIALLY REMODELS THE BRAIN TRANSCRIPTOME

2008 ◽  
Vol 32 (6s1) ◽  
pp. 368A-368A
Author(s):  
Julie A. Owen ◽  
Oscar Velasquez ◽  
Patricia S. Levin ◽  
Yan Wang ◽  
Harish Krishnan ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Adult Mice ◽  
Brain Transcriptome ◽  
The Brain

Variant calling from RNA-seq data of the brain transcriptome of pigs and its application for allele-specific expression and imprinting analysis

Gene ◽  
2018 ◽  
Vol 641 ◽  
pp. 367-375 ◽  
Author(s):  
Maria Oczkowicz ◽  
Tomasz Szmatoła ◽  
Katarzyna Piórkowska ◽  
Katarzyna Ropka-Molik
Keyword(s):  
Variant Calling ◽  
Rna Seq ◽  
Specific Expression ◽  
Allele Specific Expression ◽  
Brain Transcriptome ◽  
Allele Specific ◽  
The Brain

scholarly journals Abdominal Vagal Afferents Modulate the Brain Transcriptome and Behaviors Relevant to Schizophrenia

2018 ◽  
Vol 38 (7) ◽  
pp. 1634-1647 ◽  
Author(s):  
Melanie Klarer ◽  
Jean-Philippe Krieger ◽  
Juliet Richetto ◽  
Ulrike Weber-Stadlbauer ◽  
Lydia Günther ◽  
...  
Keyword(s):  
Vagal Afferents ◽  
Brain Transcriptome ◽  
And Behaviors ◽  
The Brain

Circular RNAs: The Brain Transcriptome Comes Full Circle

2020 ◽  
Vol 43 (10) ◽  
pp. 752-766 ◽  
Author(s):  
Akira Gokool ◽  
Clement T. Loy ◽  
Glenda M. Halliday ◽  
Irina Voineagu
Keyword(s):  
Circular Rnas ◽  
Full Circle ◽  
Brain Transcriptome ◽  
The Brain

scholarly journals A review of sleep deprivation studies evaluating the brain transcriptome

SpringerPlus ◽  
2014 ◽  
Vol 3 (1) ◽  
pp. 728 ◽  
Author(s):  
Alisa S Elliott ◽  
Jason D Huber ◽  
James P O’Callaghan ◽  
Charles L Rosen ◽  
Diane B Miller
Keyword(s):  
Sleep Deprivation ◽  
Brain Transcriptome ◽  
The Brain

scholarly journals Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders

2019 ◽  
Vol 20 (9) ◽  
pp. 2270 ◽  
Author(s):  
Maryam Ardalan ◽  
Tetyana Chumak ◽  
Zinaida Vexler ◽  
Carina Mallard
Keyword(s):  
Developmental Trajectories ◽  
Neuropsychiatric Disorders ◽  
Brain Regions ◽  
Inflammatory Reactions ◽  
Glia Cells ◽  
Complex Interactions ◽  
Early Life Programming ◽  
Brain Transcriptome ◽  
Attention Deficit Hyperactivity Disorders ◽  
The Brain

Individuals born preterm have higher rates of neurodevelopmental disorders such as schizophrenia, autistic spectrum, and attention deficit/hyperactivity disorders. These conditions are often sexually dimorphic and with different developmental trajectories. The etiology is likely multifactorial, however, infections both during pregnancy and in childhood have emerged as important risk factors. The association between sex- and age-dependent vulnerability to neuropsychiatric disorders has been suggested to relate to immune activation in the brain, including complex interactions between sex hormones, brain transcriptome, activation of glia cells, and cytokine production. Here, we will review sex-dependent effects on brain development, including glia cells, both under normal physiological conditions and following perinatal inflammation. Emphasis will be given to sex-dependent effects on brain regions which play a role in neuropsychiatric disorders and inflammatory reactions that may underlie early-life programming of neurobehavioral disturbances later in life.

Neuroprotective Effects of Peptides in the Brain: Transcriptome Approach

2020 ◽  
Vol 85 (3) ◽  
pp. 279-287
Author(s):  
I. B. Filippenkov ◽  
L. V. Dergunova ◽  
S. A. Limborska ◽  
N. F. Myasoedov
Keyword(s):  
Neuroprotective Effects ◽  
Brain Transcriptome ◽  
The Brain
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