Molecular mechanisms of memory reconsolidation

2007 ◽  
Vol 8 (4) ◽  
pp. 262-275 ◽  
Author(s):  
Natalie C. Tronson ◽  
Jane R. Taylor
Keyword(s):  
Molecular Mechanisms ◽  
Memory Reconsolidation ◽  
Mechanisms Of Memory

scholarly journals The Role and Mechanisms of Action of Glucocorticoid Involvement in Memory Storage

1998 ◽  
Vol 6 (3) ◽  
pp. 41-52 ◽  
Author(s):  
Carmen Sandi
Keyword(s):  
Glucocorticoid Receptors ◽  
Molecular Mechanisms ◽  
Memory Formation ◽  
Contextual Fear Conditioning ◽  
Memory Storage ◽  
Long Term Memory ◽  
Contextual Fear ◽  
Adrenal Steroid ◽  
Response To Stress ◽  
Mechanisms Of Memory

Adrenal steroid hormones modulate learning and memory processes by interacting with specific glucocorticoid receptors at different brain areas. In this article, certain components of the physiological response to stress elicited by learning situations are proposed to form an integral aspect of the neurobiological mechanism underlying memory formation. By reviewing the work carried out in different learning models in chicks (passive avoidance learning) and rats (spatial orientation in the Morris water maze and contextual fear conditioning), a role for brain corticosterone action through the glucocorticoid receptor type on the mechanisms of memory consolidation is hypothesized. Evidence is also presented to relate post-training corticosterone levels to the strength of memory storage. Finally, the possible molecular mechanisms that might mediate the influences of glucocorticoids in synaptic plasticity subserving long-term memory formation are considered, mainly by focusing on studies implicating a steroid action through (i) glutamatergic transmission and (ii) cell adhesion molecules.

scholarly journals Cellular and molecular mechanisms of memory T-cell survival

2009 ◽  
Vol 8 (3) ◽  
pp. 299-312 ◽  
Author(s):  
Andre Tanel ◽  
Simone G Fonseca ◽  
Bader Yassine-Diab ◽  
Rebeka Bordi ◽  
Joumana Zeidan ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Survival ◽  
Molecular Mechanisms ◽  
Memory T Cell ◽  
Mechanisms Of Memory ◽  
T Cell Survival

Molecular Mechanisms of Memory Storage inAplysia

2006 ◽  
Vol 210 (3) ◽  
pp. 174-191 ◽  
Author(s):  
Robert D. Hawkins ◽  
Eric R. Kandel ◽  
Craig H. Bailey
Keyword(s):  
Molecular Mechanisms ◽  
Memory Storage ◽  
Mechanisms Of Memory

Molecular mechanisms of synaptic consolidation during sleep: BDNF function and dendritic protein synthesis

2005 ◽  
Vol 28 (1) ◽  
pp. 65-66
Author(s):  
Clive R. Bramham
Keyword(s):  
Memory Consolidation ◽  
Molecular Mechanisms ◽  
Long Term Potentiation ◽  
Term Potentiation ◽  
Dendritic Protein Synthesis ◽  
Mechanisms Of Memory ◽  
Activity Dependent ◽  
Specific Contribution

Insights into the role of sleep in the molecular mechanisms of memory consolidation may come from studies of activity-dependent synaptic plasticity, such as long-term potentiation (LTP). This commentary posits a specific contribution of sleep to LTP stabilization, in which mRNA transported to dendrites during wakefulness is translated during sleep. Brain-derived neurotrophic factor may drive the translation of newly transported and resident mRNA.

The role of DNA methylation in the mechanisms of memory reconsolidation and development of amnesia

2015 ◽  
Vol 279 ◽  
pp. 148-154 ◽  
Author(s):  
V.P. Nikitin ◽  
S.V. Solntseva ◽  
P.V. Nikitin ◽  
S.A. Kozyrev
Keyword(s):  
Dna Methylation ◽  
Memory Reconsolidation ◽  
Mechanisms Of Memory

Molecular mechanisms of memory formation

1991 ◽  
Vol 5 (2-4) ◽  
pp. 333-350 ◽  
Author(s):  
K. T. Ng ◽  
M. E. Gibbs ◽  
S. F. Crowe ◽  
G. L. Sedman ◽  
F. Hua ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Memory Formation ◽  
Mechanisms Of Memory

Neural plasticity and memory: molecular mechanism

2015 ◽  
Vol 26 (3) ◽  
Author(s):  
Zareen Amtul ◽  
Atta-ur-Rahman
Keyword(s):  
Neural Plasticity ◽  
Molecular Mechanisms ◽  
Mrna Translation ◽  
Information Storage ◽  
Memory Storage ◽  
Cognitive Information ◽  
Intramolecular Bonding ◽  
Mechanisms Of Memory ◽  
The Individual

AbstractDeciphering the cellular and molecular mechanisms of memory has been an important topic encompassing the learning and memory domain besides the neurodegenerative disorders. Synapses accumulate cognitive information from life-lasting alterations of their molecular and structural composition. Current memory storage models identify posttranslational modification imperative for short-term information storage and mRNA translation for long-term information storage. However, the precise account of these modifications has not been summarized at the individual synapse level. Therefore, herein we describe the spatiotemporal reorganization of synaptic plasticity at the dendritic spine level to elucidate the mechanism through which synaptic substructures are remodeled; though at the molecular level, such mechanisms are still quite unclear. It has thus been concluded that the existing mechanisms do not entirely elaborate memory storage processes. Further efforts are therefore encouraged to delineate the mechanism of neuronal connectivity at the chemical level as well, including inter- or intramolecular bonding patterns at the synaptic level, which may be a permissive and vital step of memory storage.

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