scholarly journals Polintons: a hotbed of eukaryotic virus, transposon and plasmid evolution

2014 ◽  
Vol 13 (2) ◽  
pp. 105-115 ◽  
Author(s):  
Mart Krupovic ◽  
Eugene V. Koonin
1991 ◽  
Vol 16 (4) ◽  
pp. 601-614 ◽  
Author(s):  
Francois Paulus ◽  
Jean Canaday ◽  
Florence Vincent ◽  
G�raldine Bonnard ◽  
Christa Kares ◽  
...  

2020 ◽  
Vol 30 (19) ◽  
pp. R1158-R1163
Author(s):  
Tanita Wein ◽  
Tal Dagan
Keyword(s):  

Nature ◽  
1976 ◽  
Vol 263 (5580) ◽  
pp. 731-734 ◽  
Author(s):  
Stanley N. Cohen

2005 ◽  
Vol 187 (17) ◽  
pp. 5977-5983 ◽  
Author(s):  
Alena Dabrazhynetskaya ◽  
Kirill Sergueev ◽  
Stuart Austin

ABSTRACT The P1par family of active plasmid partition systems consists of at least six members, broadly distributed in a variety of plasmid types and bacterial genera. Each encodes two Par proteins and contains a cis-acting parS site. Individual par systems can show distinct species specificities; the proteins from one type cannot function with the parS site of another. P1par-versus-P7par specificity resides within two hexamer BoxB repeats encoded by parS that contact the ParB protein near the carboxy terminus. Here, we examine the species specificity differences between Yersinia pestis pMT1parS and Escherichia coli P1 and P7parS. pMT1parS site specificity could be altered to that of either P1 or P7 by point mutation changes in the BoxB repeats. Just one base change in a single BoxB repeat sometimes sufficed. The BoxB sequence appears to be able to adopt a number of forms that define exclusive interactions with different ParB species. The looped parS structure may facilitate this repertoire of interaction specificities. Different P1par family members have different partition-mediated incompatibility specificities. This property defines whether two related plasmids can coexist in the same cell and is important in promoting the evolution of new plasmid species. BoxB sequence changes that switch species specificity between P1, P7, and pMT1 species switched partition-mediated plasmid incompatibility in concert. Thus, there is a direct mechanistic link between species specificity and partition-mediated incompatibility, and the BoxB-ParB interaction can be regarded as a special mechanism for facilitating plasmid evolution.


2010 ◽  
Vol 54 (8) ◽  
pp. 3534-3534 ◽  
Author(s):  
M. A. Toleman ◽  
T. R. Walsh ◽  
D. R. Call

2014 ◽  
Vol 69 (9) ◽  
pp. 2388-2393 ◽  
Author(s):  
Monika Dolejska ◽  
Laura Villa ◽  
Marco Minoia ◽  
Luca Guardabassi ◽  
Alessandra Carattoli

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