Antibody modeling using the Prediction of ImmunoGlobulin Structure (PIGS) web server

2014 ◽  
Vol 9 (12) ◽  
pp. 2771-2783 ◽  
Author(s):  
Paolo Marcatili ◽  
Pier Paolo Olimpieri ◽  
Anna Chailyan ◽  
Anna Tramontano
Keyword(s):  
Web Server ◽  
Antibody Modeling

scholarly journals Erratum: Antibody modeling using the Prediction of ImmunoGlobulin Structure (PIGS) web server

2015 ◽  
Vol 10 (4) ◽  
pp. 644-644 ◽  
Author(s):  
Paolo Marcatili ◽  
Pier Paolo Olimpieri ◽  
Anna Chailyan ◽  
Anna Tramontano
Keyword(s):  
Web Server ◽  
Antibody Modeling

scholarly journals Modeling and docking antibody structures with Rosetta

2016 ◽  
Author(s):  
Brian D. Weitzner ◽  
Jeliazko R. Jeliazkov ◽  
Sergey Lyskov ◽  
Nicholas Marze ◽  
Daisuke Kuroda ◽  
...  
Keyword(s):  
Model Uncertainty ◽  
De Novo ◽  
Three Dimensional ◽  
Web Server ◽  
Relative Orientation ◽  
Dimensional Structure ◽  
Multiple Models ◽  
Loop Conformations ◽  
Complementarity Determining Region ◽  
Antibody Modeling

ABSTRACTWe describe Rosetta-based computational protocols for predicting the three-dimensional structure of an antibody from sequence and then docking the antibody–protein-antigen complexes. Antibody modeling leverages canonical loop conformations to graft large segments from experimentally-determined structures as well as (1) energetic calculations to minimize loops, (2) docking methodology to refine the VL–VH relative orientation, and (3) de novo prediction of the elusive complementarity determining region (CDR) H3 loop. To alleviate model uncertainty, antibody–antigen docking resamples CDR loop conformations and can use multiple models to represent an ensemble of conformations for the antibody, the antigen or both. These protocols can be run fully-automated via the ROSIE web server or manually on a computer with user control of individual steps. For best results, the protocol requires roughly 2,500 CPU-hours for antibody modeling and 250 CPU-hours for antibody–antigen docking. Tasks can be completed in under a day by using public supercomputers.

Jurnal uji web serber

2020 ◽  
Author(s):  
Wawan saputra
Keyword(s):  
Web Server ◽  
Word Wide Web

Web server adalah tulang belakang dari word wide web(www)

APLIKASI PENCARI INFORMASI PERMINTAAN LAYANAN WEB YANG ERROR MENGGUNAKAN ALGORITMA BOYER-MOORE

2016 ◽  
Vol 1 (1) ◽  
pp. 001
Author(s):  
Harry Setya Hadi
Keyword(s):  
Data Storage ◽  
Computer Network ◽  
Web Server ◽  
Access Methods ◽  
Ip Address ◽  
String Searching ◽  
Common Process ◽  
Web Server Logs ◽  
Different Parts ◽  
The Web

String searching is a common process in the processes that made the computer because the text is the main form of data storage. Boyer-Moore is the search string from right to left is considered the most efficient methods in practice, and matching string from the specified direction specifically an algorithm that has the best results theoretically. A system that is connected to a computer network that literally pick a web server that is accessed by multiple users in different parts of both good and bad aim. Any activity performed by the user, will be stored in Web server logs. With a log report contained in the web server can help a web server administrator to search the web request error. Web server log is a record of the activities of a web site that contains the data associated with the IP address, time of access, the page is opened, activities, and access methods. The amount of data contained in the resulting log is a log shed useful information.

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