scholarly journals Proteins of the XMRV retrovirus implicated in chronic fatigue syndrome and prostate cancer are homologous to human proteins relevant to both diseases.

2010 ◽  
Author(s):  
Christopher Carter ◽  
Christopher Carter
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome ◽  
Human Proteins

scholarly journals Raltegravir Is a Potent Inhibitor of XMRV, a Virus Implicated in Prostate Cancer and Chronic Fatigue Syndrome

PLoS ONE ◽  
2010 ◽  
Vol 5 (4) ◽  
pp. e9948 ◽  
Author(s):  
Ila R. Singh ◽  
John E. Gorzynski ◽  
Daria Drobysheva ◽  
Leda Bassit ◽  
Raymond F. Schinazi
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Potent Inhibitor ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

The human retrovirus XMRV in prostate cancer and chronic fatigue syndrome

2010 ◽  
Vol 7 (7) ◽  
pp. 392-402 ◽  
Author(s):  
Robert H. Silverman ◽  
Carvell Nguyen ◽  
Christopher J. Weight ◽  
Eric A. Klein
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome ◽  
Human Retrovirus

scholarly journals Phylogeny-Directed Search for Murine Leukemia Virus-Like Retroviruses in Vertebrate Genomes and in Patients Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Prostate Cancer

2011 ◽  
Vol 2011 ◽  
pp. 1-20 ◽  
Author(s):  
Jonas Blomberg ◽  
Ali Sheikholvaezin ◽  
Amal Elfaitouri ◽  
Fredrik Blomberg ◽  
Anna Sjösten ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Optimal Strategies ◽  
Chronic Fatigue ◽  
Myalgic Encephalomyelitis ◽  
Directed Search ◽  
Fatigue Syndrome ◽  
Murine Leukemia

Gammaretrovirus-like sequences occur in most vertebrate genomes. Murine Leukemia Virus (MLV) like retroviruses (MLLVs) are a subset, which may be pathogenic and spread cross-species. Retroviruses highly similar to MLLVs (xenotropic murine retrovirus related virus (XMRV) and Human Mouse retrovirus-like RetroViruses (HMRVs)) reported from patients suffering from prostate cancer (PC) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) raise the possibility that also humans have been infected. Structurally intact, potentially infectious MLLVs occur in the genomes of some mammals, especially mouse. Mouse MLLVs contain three major groups. One, MERV G3, contained MLVs and XMRV/HMRV. Its presence in mouse DNA, and the abundance of xenotropic MLVs in biologicals, is a source of false positivity. Theoretically, XMRV/HMRV could be one of several MLLV transspecies infections. MLLV pathobiology and diversity indicate optimal strategies for investigating XMRV/HMRV in humans and raise ethical concerns. The alternatives that XMRV/HMRV may give a hard-to-detect “stealth” infection, or that XMRV/HMRV never reached humans, have to be considered.

scholarly journals XMRV, prostate cancer and chronic fatigue syndrome

2011 ◽  
Vol 98 (1) ◽  
pp. 61-74 ◽  
Author(s):  
J. C. Kenyon ◽  
A. M. L. Lever
Keyword(s):  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

scholarly journals Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome

2013 ◽  
Vol 38 (12) ◽  
pp. 2983-2995 ◽  
Author(s):  
Kathleen C. Light ◽  
Neeraj Agarwal ◽  
Eli Iacob ◽  
Andrea T. White ◽  
Anita Y. Kinney ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Chronic Fatigue Syndrome ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Chronic Fatigue ◽  
Fatigue Syndrome
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