scholarly journals Cortical Thickness and Subcortical Gray Matter Volume in Pediatric Anxiety Disorders

2017 ◽  
Vol 42 (12) ◽  
pp. 2423-2433 ◽  
Author(s):  
Andrea L Gold ◽  
Elizabeth R Steuber ◽  
Lauren K White ◽  
Jennifer Pacheco ◽  
Jessica F Sachs ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume ◽  
Pediatric Anxiety ◽  
Pediatric Anxiety Disorders

scholarly journals Effects of Meditation on Structural Changes of the Brain in Patients With Mild Cognitive Impairment or Alzheimer’s Disease Dementia

2021 ◽  
Vol 15 ◽  
Author(s):  
Madhukar Dwivedi ◽  
Neha Dubey ◽  
Aditya Jain Pansari ◽  
Raju Surampudi Bapi ◽  
Meghoranjani Das ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Brain Areas ◽  
Hippocampal Subfields ◽  
Matter Volume ◽  
The Right ◽  
The Brain

Previous cross-sectional studies reported positive effects of meditation on the brain areas related to attention and executive function in the healthy elderly population. Effects of long-term regular meditation in persons with mild cognitive impairment (MCI) and Alzheimer’s disease dementia (AD) have rarely been studied. In this study, we explored changes in cortical thickness and gray matter volume in meditation-naïve persons with MCI or mild AD after long-term meditation intervention. MCI or mild AD patients underwent detailed clinical and neuropsychological assessment and were assigned into meditation or non-meditation groups. High resolution T1-weighted magnetic resonance images (MRI) were acquired at baseline and after 6 months. Longitudinal symmetrized percentage changes (SPC) in cortical thickness and gray matter volume were estimated. Left caudal middle frontal, left rostral middle frontal, left superior parietal, right lateral orbitofrontal, and right superior frontal cortices showed changes in both cortical thickness and gray matter volume; the left paracentral cortex showed changes in cortical thickness; the left lateral occipital, left superior frontal, left banks of the superior temporal sulcus (bankssts), and left medial orbitofrontal cortices showed changes in gray matter volume. All these areas exhibited significantly higher SPC values in meditators as compared to non-meditators. Conversely, the left lateral occipital, and right posterior cingulate cortices showed significantly lower SPC values for cortical thickness in the meditators. In hippocampal subfields analysis, we observed significantly higher SPC in gray matter volume of the left CA1, molecular layer HP, and CA3 with a trend for increased gray matter volume in most other areas. No significant changes were found for the hippocampal subfields in the right hemisphere. Analysis of the subcortical structures revealed significantly increased volume in the right thalamus in the meditation group. The results of the study point out that long-term meditation practice in persons with MCI or mild AD leads to salutary changes in cortical thickness and gray matter volumes. Most of these changes were observed in the brain areas related to executive control and memory that are prominently at risk in neurodegenerative diseases.

Longitudinal assessment of subcortical gray matter volume, cortical thickness, and white matter integrity in HIV-positive patients

2016 ◽  
Vol 44 (5) ◽  
pp. 1262-1269 ◽  
Author(s):  
Diogo Goulart Corrêa ◽  
Nicolle Zimmermann ◽  
Gustavo Tukamoto ◽  
Thomas Doring ◽  
Nina Ventura ◽  
...  
Keyword(s):  
White Matter ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
White Matter Integrity ◽  
Hiv Positive ◽  
Longitudinal Assessment ◽  
Matter Volume

Mapping gray matter volume and cortical thickness in Alzheimer's disease

2010 ◽  
Author(s):  
Xiaojuan Guo ◽  
Ziyi Li ◽  
Kewei Chen ◽  
Li Yao ◽  
Zhiqun Wang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume

scholarly journals Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume?

2012 ◽  
Vol 33 (3) ◽  
pp. 617.e1-617.e9 ◽  
Author(s):  
Herve Lemaitre ◽  
Aaron L. Goldman ◽  
Fabio Sambataro ◽  
Beth A. Verchinski ◽  
Andreas Meyer-Lindenberg ◽  
...  
Keyword(s):  
Surface Area ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume ◽  
Age Related

scholarly journals Reduced gray matter volume and cortical thickness associated with traffic-related air pollution in a longitudinally studied pediatric cohort

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0228092 ◽  
Author(s):  
Travis Beckwith ◽  
Kim Cecil ◽  
Mekibib Altaye ◽  
Rachel Severs ◽  
Christopher Wolfe ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cortical Thickness ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume

Electroconvulsive therapy increases temporal gray matter volume and cortical thickness

2016 ◽  
Vol 26 (3) ◽  
pp. 506-517 ◽  
Author(s):  
Alexander Sartorius ◽  
Traute Demirakca ◽  
Andreas Böhringer ◽  
Christian Clemm von Hohenberg ◽  
Suna Su Aksay ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Electroconvulsive Therapy ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume

scholarly journals The mediating role of cortical thickness and gray matter volume on sleep slow-wave activity during adolescence

2017 ◽  
Vol 223 (2) ◽  
pp. 669-685 ◽  
Author(s):  
Aimée Goldstone ◽  
Adrian R. Willoughby ◽  
Massimiliano de Zambotti ◽  
Peter L. Franzen ◽  
Dongjin Kwon ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Slow Wave ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Mediating Role ◽  
Matter Volume

scholarly journals Gray Matter Volume Abnormalities in Depressive Patients With and Without Anxiety Disorders

Medicine ◽  
2014 ◽  
Vol 93 (29) ◽  
pp. e345 ◽  
Author(s):  
Haochen Qi ◽  
Yuping Ning ◽  
Jie Li ◽  
Shengwen Guo ◽  
Minyue Chi ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Matter Volume ◽  
Depressive Patients

scholarly journals Association of Plasma Complement System With Brain Structure Deficits in Bipolar and Major Depressive Disorders

2021 ◽  
Author(s):  
Hua Yu ◽  
Peiyan Ni ◽  
Yang Tian ◽  
Liansheng Zhao ◽  
Mingli Li ◽  
...  
Keyword(s):  
Cortical Thickness ◽  
Gray Matter ◽  
Brain Structure ◽  
Gray Matter Volume ◽  
Factor H ◽  
Major Depressive ◽  
Complement Components ◽  
Factor B ◽  
Matter Volume ◽  
Patient Groups

Abstract Objective Inflammation plays a crucial role in the pathogenesis of major depressive disorder (MDD) and bipolar disorder (BD). However, the underlying neurobiological mechanisms are poorly understood. This study aimed to examine whether the dysregulation of complement components contributes to brain structure deficits in BD and MDD patients. Methods A total of 52 BD patients, 35 MDD patients, and 53 mentally healthy controls were recruited from the inpatient and outpatient departments of West China Hospital of Sichuan University. The human complement panel 2-immunology multiplex assay was used to measure the levels of complement C1q, C3, C3b, C4, factor B, factor H, and properdin. Whole brain-based comparison was performed to investigate differences in gray matter volume and cortical thickness among the BD, MDD, and control groups, and relationships were explored between neuroanatomical differences and levels of complement components.Results The gray matter volume in the medial orbital frontal cortex (mOFC) and middle cingulum decreased in both patient groups, while the cortical thickness of the left precentral and left superior frontal gyrus was affected differently. Log10-transformed concentrations of C1q, C4, factor B, factor H, and properdin were higher in both patient groups than in controls, while levels of C1q, factor H, and properdin showed a significant negative correlation with gray matter volume in the mOFC at the voxel-wise level.Conclusion Greater inflammation in mOFC was observed in BD and MDD patients than in controls. Structural deficits in both patient groups were associated with elevated levels of certain complement factors, providing insight into the neuro-inflammatory pathogenesis of mood disorders.

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