The GABAB Positive Allosteric Modulator ADX71441 Attenuates Alcohol Self-Administration and Relapse to Alcohol Seeking in Rats

Eric Augier; Russell S Dulman; Ruslan Damadzic; Andrew Pilling; J Paul Hamilton; Markus Heilig

doi:10.1038/npp.2017.53

The GABAB Positive Allosteric Modulator ADX71441 Attenuates Alcohol Self-Administration and Relapse to Alcohol Seeking in Rats

Neuropsychopharmacology ◽

10.1038/npp.2017.53 ◽

2017 ◽

Vol 42 (9) ◽

pp. 1789-1799 ◽

Cited By ~ 25

Author(s):

Eric Augier ◽

Russell S Dulman ◽

Ruslan Damadzic ◽

Andrew Pilling ◽

J Paul Hamilton ◽

...

Keyword(s):

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator ◽

Alcohol Seeking

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Suppressing effect of CMPPE, a new positive allosteric modulator of the GABAB receptor, on alcohol self-administration and reinstatement of alcohol seeking in rats

Alcohol ◽

10.1016/j.alcohol.2018.05.015 ◽

2019 ◽

Vol 75 ◽

pp. 79-87 ◽

Cited By ~ 5

Author(s):

Paola Maccioni ◽

Federica Fara ◽

Irene Lorrai ◽

Carla Acciaro ◽

Claudia Mugnaini ◽

...

Keyword(s):

Gabab Receptor ◽

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator ◽

Alcohol Seeking

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The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys

Biological Psychiatry ◽

10.1016/j.biopsych.2015.01.014 ◽

2015 ◽

Vol 78 (7) ◽

pp. 452-462 ◽

Cited By ~ 32

Author(s):

Zuzana Justinova ◽

Leigh V. Panlilio ◽

Maria E. Secci ◽

Godfrey H. Redhi ◽

Charles W. Schindler ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Squirrel Monkeys ◽

Allosteric Modulator ◽

The Novel ◽

Self Administration ◽

Positive Allosteric Modulator ◽

Metabotropic Glutamate

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The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats

Neuropsychopharmacology ◽

10.1038/npp.2016.107 ◽

2016 ◽

Vol 41 (12) ◽

pp. 2932-2940 ◽

Cited By ~ 17

Author(s):

Eric Augier ◽

Russell S Dulman ◽

Caroline Rauffenbart ◽

Gaëlle Augier ◽

Alan J Cross ◽

...

Keyword(s):

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Alcohol Seeking

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Design and Synthesis of an Orally Active Metabotropic Glutamate Receptor Subtype-2 (mGluR2) Positive Allosteric Modulator (PAM) That Decreases Cocaine Self-Administration in Rats

Journal of Medicinal Chemistry ◽

10.1021/jm1012165 ◽

2011 ◽

Vol 54 (1) ◽

pp. 342-353 ◽

Cited By ~ 34

Author(s):

Raveendra-Panickar Dhanya ◽

Shyama Sidique ◽

Douglas J. Sheffler ◽

Hilary Highfield Nickols ◽

Ananda Herath ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Subtype ◽

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator ◽

Metabotropic Glutamate ◽

Design And Synthesis ◽

Orally Active

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The GABAB receptor positive allosteric modulator ASP8062 reduces operant alcohol self-administration in male and female Sprague Dawley rats

Psychopharmacology ◽

10.1007/s00213-021-05881-0 ◽

2021 ◽

Author(s):

Colin N. Haile ◽

Benjamin A. Carper ◽

Tracy L. Nolen ◽

Therese A. Kosten

Keyword(s):

Gabab Receptor ◽

Allosteric Modulator ◽

Sprague Dawley ◽

Self Administration ◽

Positive Allosteric Modulator ◽

Male And Female ◽

Sprague Dawley Rats

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Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082

Pharmacology Biochemistry and Behavior ◽

10.1016/j.pbb.2008.06.006 ◽

2008 ◽

Vol 91 (1) ◽

pp. 14-20 ◽

Cited By ~ 40

Author(s):

M SALLING ◽

S FACCIDOMO ◽

C HODGE

Keyword(s):

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator

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Comparison of the Effect of the GABABReceptor Agonist, Baclofen, and the Positive Allosteric Modulator of the GABABReceptor, GS39783, on Alcohol Self-Administration in 3 Different Lines of Alcohol-Preferring Rats

Alcoholism Clinical and Experimental Research ◽

10.1111/j.1530-0277.2012.01782.x ◽

2012 ◽

Vol 36 (10) ◽

pp. 1748-1766 ◽

Cited By ~ 50

Author(s):

Paola Maccioni ◽

Alessandro Zaru ◽

Barbara Loi ◽

Carla Lobina ◽

Mauro A. M. Carai ◽

...

Keyword(s):

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator

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KK-92A, a novel GABAB receptor positive allosteric modulator, attenuates nicotine self-administration and cue-induced nicotine seeking in rats

Psychopharmacology ◽

10.1007/s00213-017-4594-9 ◽

2017 ◽

Vol 234 (9-10) ◽

pp. 1633-1644 ◽

Cited By ~ 7

Author(s):

Xia Li ◽

Emmanuel Sturchler ◽

Katarzyna Kaczanowska ◽

Michael Cameron ◽

M. G. Finn ◽

...

Keyword(s):

Gabab Receptor ◽

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator

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Faculty Opinions recommendation of The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726446227.793520386 ◽

2016 ◽

Author(s):

Yavin Shaham ◽

Daniele Caprioli

Keyword(s):

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Alcohol Seeking

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P.2.004 Nonsedative doses of a GABA-B positive allosteric modulator normalise VTA neuroadaptations and self-administration induced by drugs of abuse in mice

European Neuropsychopharmacology ◽

10.1016/s0924-977x(16)70031-9 ◽

2016 ◽

Vol 26 ◽

pp. S28

Author(s):

E. Vashchinkina ◽

O. Vekovischeva ◽

A.M. Linden ◽

P. Hyytia ◽

E. Korpi

Keyword(s):

Drugs Of Abuse ◽

Allosteric Modulator ◽

Self Administration ◽

Positive Allosteric Modulator

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