scholarly journals Protein Markers of Neurotransmitter Synthesis and Release in Postmortem Schizophrenia Substantia Nigra

2016 ◽  
Vol 42 (2) ◽  
pp. 540-550 ◽  
Author(s):  
Kirsten E Schoonover ◽  
Lesley A McCollum ◽  
Rosalinda C Roberts
Keyword(s):  
Substantia Nigra ◽  
Protein Markers ◽  
Neurotransmitter Synthesis

Immunocytochemical methodology for the localization of neuronal antigens at the ultrastructural level

1990 ◽  
Vol 48 (3) ◽  
pp. 876-877
Author(s):  
Jorge Pecci Saavedra ◽  
Mark Connaughton ◽  
Juan José López ◽  
Alicia Brusco
Keyword(s):  
Spinal Cord ◽  
Substantia Nigra ◽  
Polyclonal Antibodies ◽  
Ultrastructural Level ◽  
Point Of View ◽  
Nerve Tissue ◽  
Tissue Fixation ◽  
Optimal Conditions ◽  
Interpeduncular Nucleus ◽  
Technical Point

The use of antibodies as labels for the localization of specific molecules in the nervous systan has been extensively applied in recent years. Both monoand polyclonal antibodies or antisera have been employed. The knowledge of the organization of neuronal connectivities, gliovascular relationships, glioneuronal relationships and other features of nerve tissue has greatly increased.A number of areas of the nervous systan have been analyzed in our laboratory, including the nuclei of the raphe system, the reticular formation, interpeduncular nucleus, substantia nigra, caudate nucleus, putamen, pallidum, spinal cord, pineal gland and others.From a technical point of view, a number of variables needed to be taken into account in order to obtain reliable and reproducible results. The design of the optimal conditions of tissue fixation, embedding, sectioning, dilution of antibodies, and adaptation of Sternberger PAP technique were sane of the parameters taken into account to optimize the results. It is critical that each step of the technique be defined for each particular case.

Diagnostic evaluation of the substantia nigra

1996 ◽  
Vol 22 (3) ◽  
pp. 228-232 ◽  
Author(s):  
D. A. McRitchie ◽  
G. M. Halliday ◽  
R. Pamphlett
Keyword(s):  
Substantia Nigra ◽  
Diagnostic Evaluation

Hyperechogenicity of substantia nigra in Parkinson's disease – Searching for genetic predictors

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
C Funke ◽  
A Soehn ◽  
C Schulte ◽  
M Bonin ◽  
C Klein ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Substantia Nigra ◽  
Genetic Predictors

Substantia nigra hyperechogenicity and CSF dopamine depletion in HIV

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
J Thiermann ◽  
M Obermann ◽  
M Küper ◽  
O Kastrup ◽  
Ö Yaldizli ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
Dopamine Depletion ◽  
Substantia Nigra Hyperechogenicity

Funktionelle und strukturelle Konnektivität beim M. Parkinson mit moderater und hoher Hyperechogenität der Substantia Nigra

2012 ◽  
Vol 43 (01) ◽  
Author(s):  
M Al-Khaled ◽  
M Heldmann ◽  
C Erdmann ◽  
M Göttlich ◽  
C Klein ◽  
...  
Keyword(s):  
Substantia Nigra
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