scholarly journals Intravenous Nicotine Self-Administration in Smokers: Dose–Response Function and Sex Differences

2015 ◽  
Vol 41 (8) ◽  
pp. 2034-2040 ◽  
Author(s):  
Kevin P Jensen ◽  
Elise E DeVito ◽  
Gerald Valentine ◽  
Ralitza Gueorguieva ◽  
Mehmet Sofuoglu
Keyword(s):  
Sex Differences ◽  
Response Function ◽  
Dose Response ◽  
Self Administration ◽  
Intravenous Nicotine ◽  
Dose Response Function

scholarly journals Encoding fear intensity in human sweat

2020 ◽  
Vol 375 (1800) ◽  
pp. 20190271 ◽  
Author(s):  
Jasper H. B. de Groot ◽  
Peter A. Kirk ◽  
Jay A. Gottfried
Keyword(s):  
Response Function ◽  
Dose Response ◽  
Physiological Data ◽  
Olfactory Communication ◽  
Film Clips ◽  
Combination Of Methods ◽  
Multivariate Pattern ◽  
And Control ◽  
Photo Ionization ◽  
Dose Response Function

Humans, like other animals, have an excellent sense of smell that can serve social communication. Although ample research has shown that body odours can convey transient emotions like fear, these studies have exclusively treated emotions as categorical , neglecting the question whether emotion quantity can be expressed chemically. Using a unique combination of methods and techniques, we explored a dose–response function: Can experienced fear intensity be encoded in fear sweat? Specifically, fear experience was quantified using multivariate pattern classification (combining physiological data and subjective feelings with partial least-squares-discriminant analysis), whereas a photo-ionization detector quantified volatile molecules in sweat. Thirty-six male participants donated sweat while watching scary film clips and control (calming) film clips. Both traditional univariate and novel multivariate analysis (100% classification accuracy; Q 2 : 0.76; R 2 : 0.79) underlined effective fear induction. Using their regression-weighted scores, participants were assigned significantly above chance (83% > 33%) to fear intensity categories (low–medium–high). Notably, the high fear group ( n = 12) produced higher doses of armpit sweat, and greater doses of fear sweat emitted more volatile molecules ( n = 3). This study brings new evidence to show that fear intensity is encoded in sweat (dose–response function), opening a field that examines intensity coding and decoding of other chemically communicable states/traits. This article is part of the Theo Murphy meeting issue ‘Olfactory communication in humans’.

Annual atmospheric corrosion rate and dose-response function for carbon steel in Bogotá

Atmósfera ◽  
2017 ◽  
Vol 30 (1) ◽  
pp. 53-61 ◽  
Author(s):  
John Fredy Ríos Rojas ◽  
◽  
David Aperador Rodríguez ◽  
Edwin Arbey Hernández García ◽  
Carlos Enrique Arroyave Posada ◽  
...  
Keyword(s):  
Carbon Steel ◽  
Corrosion Rate ◽  
Response Function ◽  
Dose Response ◽  
Atmospheric Corrosion ◽  
Dose Response Function

scholarly journals Rational design of a biosensor circuit with semi-log dose-response function in Escherichia coli

2013 ◽  
Vol 1 (3) ◽  
pp. 209-220 ◽  
Author(s):  
Haoqian Zhang ◽  
Ying Sheng ◽  
Qianzhu Wu ◽  
Ao Liu ◽  
Yuheng Lu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Response Function ◽  
Dose Response ◽  
Rational Design ◽  
Dose Response Function
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