scholarly journals Amygdala Transcriptome and Cellular Mechanisms Underlying Stress-Enhanced Fear Learning in a Rat Model of Posttraumatic Stress Disorder

2010 ◽  
Vol 35 (6) ◽  
pp. 1402-1411 ◽  
Author(s):  
Igor Ponomarev ◽  
Vinuta Rau ◽  
Edmond I Eger ◽  
R Adron Harris ◽  
Michael S Fanselow
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rat Model ◽  
Stress Disorder ◽  
Fear Learning ◽  
Cellular Mechanisms

Amygdala Deep Brain Stimulation Is Superior to Paroxetine Treatment in a Rat Model of Posttraumatic Stress Disorder

2013 ◽  
Vol 6 (6) ◽  
pp. 837-844 ◽  
Author(s):  
David A. Stidd ◽  
Kimberly Vogelsang ◽  
Scott E. Krahl ◽  
Jean-Philippe Langevin ◽  
Jean-Marc Fellous
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Deep Brain Stimulation ◽  
Posttraumatic Stress ◽  
Brain Stimulation ◽  
Rat Model ◽  
Stress Disorder ◽  
Paroxetine Treatment ◽  
Deep Brain

scholarly journals Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder

2015 ◽  
Vol 78 (12) ◽  
pp. 871-879 ◽  
Author(s):  
Nicole M. Enman ◽  
Kayti Arthur ◽  
Sara J. Ward ◽  
Shane A. Perrine ◽  
Ellen M. Unterwald
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rat Model ◽  
Stress Disorder ◽  
Cocaine Reward

Searching for glycomic biomarkers for predicting resilience and vulnerability in a rat model of posttraumatic stress disorder

Stress ◽  
2020 ◽  
Vol 23 (6) ◽  
pp. 715-731
Author(s):  
Csilla Lea Fazekas ◽  
Eszter Sipos ◽  
Thomas Klaric ◽  
Bibiána Török ◽  
Manon Bellardie ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rat Model ◽  
Stress Disorder

scholarly journals Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder

2015 ◽  
Vol 35 (1) ◽  
pp. 65-75 ◽  
Author(s):  
Naimesh Solanki ◽  
Isam Alkadhi ◽  
Fatin Atrooz ◽  
Gaurav Patki ◽  
Samina Salim
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rat Model ◽  
Stress Disorder ◽  
Cognitive Behavioral

Neurobiology of Trauma and Stressor-Related Disorders

2018 ◽  
Author(s):  
Marissa Elizabeth Maheu ◽  
Joseph Hunter Howie ◽  
Kerry James Ressler
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Stress Response ◽  
Posttraumatic Stress ◽  
Large Scale ◽  
Stress Disorder ◽  
Acute Stress ◽  
Molecular Techniques ◽  
Fear Learning ◽  
Recent Developments ◽  
Genomic Studies

Posttraumatic stress disorder (PTSD) and acute stress disorder are precipitated by exposure to one or more traumatic events, and result in debilitating fear-related symptoms. Advances made over the past several years have greatly improved our understanding of these disorders, as well as the neurobiological and genetic factors that contribute to their emergence and progression. In this review, we provide an overview of this research, with a particular focus on recent developments in understanding the neurocircuitry underlying relevant aspects of fear learning, including acquisition, generalization, and the extinction of fear. Molecular regulators of stress response and candidate genes implicated in PTSD are also discussed. Although there remains a great deal to learn about these disorders, novel approaches, large-scale genomic studies, and new molecular techniques promise to help untangle the neurobiology of trauma- and stressor-related illness over the coming years. This review contains 3 figures, 3 tables and 56 references Key words: Posttraumatic stress disorder, fear, genetics, GWAS, HPA stress response, neurocircuitry models of trauma, generalization, extinction learning.

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