Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

Ana Ricobaraza; Mar Cuadrado-Tejedor; Alberto Pérez-Mediavilla; Diana Frechilla; Joaquin Del Río; Ana García-Osta

doi:10.1038/npp.2008.229

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

Neuropsychopharmacology ◽

10.1038/npp.2008.229 ◽

2009 ◽

Vol 34 (7) ◽

pp. 1721-1732 ◽

Cited By ~ 232

Author(s):

Ana Ricobaraza ◽

Mar Cuadrado-Tejedor ◽

Alberto Pérez-Mediavilla ◽

Diana Frechilla ◽

Joaquin Del Río ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficit ◽

Tau Pathology

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Amelioration of Tau Pathology by Anle138b Rescues Neuronal Function in a Mouse Model of Human Alzheimer's Disease Tau

10.1055/s-0039-1683472 ◽

2019 ◽

Author(s):

M Deussing ◽

T Blume ◽

L Kaiser ◽

F Probst ◽

F Overhoff ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Neuronal Function ◽

Tau Pathology

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Correction to: Norovirus P particle-based tau vaccine-generated phosphorylated tau antibodies markedly ameliorate tau pathology and improve behavioral deficits in mouse model of Alzheimer’s disease

Signal Transduction and Targeted Therapy ◽

10.1038/s41392-021-00657-6 ◽

2021 ◽

Vol 6 (1) ◽

Author(s):

Yao Sun ◽

Yongqing Guo ◽

Xuejian Feng ◽

Lu Fu ◽

Yayuan Zheng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Phosphorylated Tau ◽

Tau Pathology ◽

Behavioral Deficits ◽

Model Of Alzheimer’S Disease

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Prebiotic Lactulose Ameliorates the Cognitive Deficit in Alzheimer’s Disease Mouse Model through Macroautophagy and Chaperone-Mediated Autophagy Pathways

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.0c07327 ◽

2021 ◽

Vol 69 (8) ◽

pp. 2422-2437 ◽

Cited By ~ 1

Author(s):

Yan-Suan Lee ◽

Dar-Ming Lai ◽

Hei-Jen Huang ◽

Guey-Jen Lee-Chen ◽

Ching-Hwa Chang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficit ◽

Chaperone Mediated Autophagy

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Longitudinal assessment of cerebral perfusion and vascular response to hypoventilation in a bigenic mouse model of Alzheimer's disease with amyloid and tau pathology

NMR in Biomedicine ◽

10.1002/nbm.4037 ◽

2018 ◽

Vol 32 (2) ◽

pp. e4037 ◽

Cited By ~ 3

Author(s):

Kristof Govaerts ◽

Benoit Lechat ◽

Tom Struys ◽

Anna Kremer ◽

Peter Borghgraef ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cerebral Perfusion ◽

Vascular Response ◽

Longitudinal Assessment ◽

Tau Pathology ◽

Model Of Alzheimer’S Disease

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9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model

Neuropharmacology ◽

10.1016/j.neuropharm.2020.108354 ◽

2020 ◽

Vol 181 ◽

pp. 108354

Author(s):

Yaojun Ju ◽

Kin Yip Tam

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Cognitive Deficit ◽

Dual Inhibitor

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Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer’s disease by restoring microglial function via a PPAR-γ-dependent mechanism

Journal of Neuroinflammation ◽

10.1186/s12974-019-1515-3 ◽

2019 ◽

Vol 16 (1) ◽

Cited By ~ 9

Author(s):

Elisa Medrano-Jiménez ◽

Itzia Jiménez-Ferrer Carrillo ◽

Martha Pedraza-Escalona ◽

Cristina E. Ramírez-Serrano ◽

Lourdes Álvarez-Arellano ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

High Fat Diet ◽

Cognitive Deficit ◽

High Fat ◽

Ppar Γ ◽

Model Of Alzheimer’S Disease ◽

Malva Parviflora ◽

Dependent Mechanism

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Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

PLoS ONE ◽

10.1371/journal.pone.0007917 ◽

2009 ◽

Vol 4 (11) ◽

pp. e7917 ◽

Cited By ~ 106

Author(s):

Yazi D. Ke ◽

Fabien Delerue ◽

Amadeus Gladbach ◽

Jürgen Götz ◽

Lars M. Ittner

Keyword(s):

Diabetes Mellitus ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Experimental Diabetes ◽

Transgenic Mouse Model ◽

Tau Pathology ◽

Experimental Diabetes Mellitus ◽

Model Of Alzheimer’S Disease

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Space radiation does not alter amyloid or tau pathology in the 3xTg mouse model of Alzheimer's disease

Life Sciences in Space Research ◽

10.1016/j.lssr.2020.08.001 ◽

2020 ◽

Vol 27 ◽

pp. 89-98

Author(s):

Laura Owlett ◽

Elizabeth K. Belcher ◽

Dawling A. Dionisio-Santos ◽

Jacqueline P. Williams ◽

John A. Olschowka ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Space Radiation ◽

Tau Pathology ◽

Model Of Alzheimer’S Disease

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High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology

Neurobiology of Aging ◽

10.1016/j.neurobiolaging.2016.07.016 ◽

2016 ◽

Vol 47 ◽

pp. 71-73 ◽

Cited By ~ 14

Author(s):

Maud Gratuze ◽

Jacinthe Julien ◽

Françoise Morin ◽

Frédéric Calon ◽

Sébastien S. Hébert ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

High Cholesterol ◽

Tau Pathology ◽

High Fat ◽

High Sugar ◽

Model Of Alzheimer’S Disease

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Amyloid and tau pathology of familial Alzheimer’s disease APP/PS1 mouse model in a senescence phenotype background (SAMP8)

AGE ◽

10.1007/s11357-015-9747-3 ◽

2015 ◽

Vol 37 (1) ◽

Cited By ~ 15

Author(s):

D. Porquet ◽

P. Andrés-Benito ◽

C. Griñán-Ferré ◽

A. Camins ◽

I. Ferrer ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Tau Pathology ◽

Familial Alzheimer’S Disease ◽

Familial Alzheimer's Disease ◽

Senescence Phenotype

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