Recent advances in nuclear physics through on-line isotope separation

2014 ◽  
Vol 10 (12) ◽  
pp. 909-913 ◽  
Author(s):  
David Gareth Jenkins
Keyword(s):  
Nuclear Physics ◽  
Isotope Separation ◽  
Recent Advances ◽  
On Line

scholarly journals Early Evaluation of Copper Radioisotope Production at ISOLPHARM

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2437 ◽  
Author(s):  
Francesca Borgna ◽  
Michele Ballan ◽  
Chiara Favaretto ◽  
Marco Verona ◽  
Marianna Tosato ◽  
...  
Keyword(s):  
Nuclear Physics ◽  
Specific Activity ◽  
Isotope Separation ◽  
Pure Copper ◽  
Mass Separation ◽  
Monte Carlo Code ◽  
Early Evaluation ◽  
On Line ◽  
Isol Facility

The ISOLPHARM (ISOL technique for radioPHARMaceuticals) project is dedicated to the development of high purity radiopharmaceuticals exploiting the radionuclides producible with the future Selective Production of Exotic Species (SPES) Isotope Separation On-Line (ISOL) facility at the Legnaro National Laboratories of the Italian National Institute for Nuclear Physics (INFN-LNL). At SPES, a proton beam (up to 70 MeV) extracted from a cyclotron will directly impinge a primary target, where the produced isotopes are released thanks to the high working temperatures (2000 °C), ionized, extracted and accelerated, and finally, after mass separation, only the desired nuclei are collected on a secondary target, free from isotopic contaminants that decrease their specific activity. A case study for such project is the evaluation of the feasibility of the ISOL production of 64Cu and 67Cu using a zirconium germanide target, currently under development. The producible activities of 64Cu and 67Cu were calculated by means of the Monte Carlo code FLUKA, whereas dedicated off-line tests with stable beams were performed at LNL to evaluate the capability to ionize and recover isotopically pure copper.

scholarly journals RIB production and related experiments at EXOTIC

2018 ◽  
Vol 184 ◽  
pp. 01012
Author(s):  
Marco Mazzocco
Keyword(s):  
Nuclear Physics ◽  
Large Scale ◽  
Isotope Separation ◽  
Big Bang ◽  
Weakly Bound ◽  
Production Techniques ◽  
On Line ◽  
Main Production ◽  
Supernova Explosions ◽  
The Big Bang

Radioactive nuclei have a very deep relevance in many astrophysical scenarios, from the Big Bang nucleo-synthesis to supernova explosions. Several Nuclear Physics laboratories around the world have been constructing large-scale facilities for the production of Radioactive Ion Beams (RIBs). The main production techniques, i.e. In-Flight and Isotope Separation On Line, which will be reviewed in this contribution. In particular, we will concentrate on the production of light weakly-bound RIBs at the facility EXOTIC, located at INFN-LNL (Italy) and we will describe the most recent experiments.

Recent advances in nuclear physics

1953 ◽  
Vol 4 (10) ◽  
pp. 289-297 ◽  
Author(s):  
Sir John Cockcroft
Keyword(s):  
Nuclear Physics ◽  
Recent Advances

scholarly journals The ISOLPHARM project: A New ISOL production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors

2018 ◽  
Vol 48 ◽  
pp. 1860103 ◽  
Author(s):  
A. Andrighetto ◽  
F. Borgna ◽  
M. Ballan ◽  
S. Corradetti ◽  
E. Vettorato ◽  
...  
Keyword(s):  
Nuclear Reactions ◽  
Specific Activity ◽  
Isotope Separation ◽  
High Specific Activity ◽  
Target Material ◽  
Mass Range ◽  
Production Method ◽  
Radioactive Isotopes ◽  
Innovative Technology ◽  
On Line

The ISOLPHARM project explores the feasibility of exploiting an innovative technology to produce extremely high specific activity beta-emitting radionuclides as radiopharmaceutical precursors. This technique is expected to produce radiopharmaceuticals that are virtually mainly impossible to obtain in standard production facilities, at lower cost and with less environmental impact than traditional techniques. The groundbreaking ISOLPHARM method investigated in this project has been granted an international patent (INFN). As a component of the SPES (Selective Production of Exotic Species) project at the Istituto Nazionale di Fisica Nucleare–Laboratori Nazionali di Legnaro (INFN–LNL), a new facility will produce radioactive ion beams of neutron-rich nuclei with high purity and a mass range of 80–160 amu. The radioactive isotopes will result from nuclear reactions induced by accelerating 40 MeV protons in a cyclotron to collide on a target of UC[Formula: see text]. The uranium in the target material will be [Formula: see text]U, yielding radioactive isotopes that belong to elements with an atomic number between 28 and 57. Isotope separation on line (ISOL) is adopted in the ISOLPHARM project to obtain pure isobaric beams for radiopharmaceutical applications, with no isotopic contaminations in the beam or subsequent trapping substrate. Isobaric contaminations may potentially affect radiochemical and radionuclide purity, but proper methods to separate chemically different elements can be developed.

scholarly journals ISOLDE target and ion source chemistry

2001 ◽  
Vol 89 (11-12) ◽  
Author(s):  
U. Köster
Keyword(s):  
Liquid Metals ◽  
Molecular Form ◽  
Isotope Separation ◽  
Thick Target ◽  
Ion Source ◽  
Resonance Ionization ◽  
Surface Ionization ◽  
Laser Ion Source ◽  
Reaction Products ◽  
On Line

For the production of radioactive ion beams by means of the ISOL (isotope separation on-line) method in which the nuclei of interest are stopped in a thick target, chemistry plays a crucial role. It serves to separate the nuclear reaction products in atomic or molecular form from the bulk target and to transfer them efficiently to an ion source. This article gives an overview of ISOLDE radiochemical methods where targets (liquid metals, solid metals, carbides and oxides) and ion sources are optimized with respect to efficiency, speed and chemical selectivity. Rather pure beams of non-metals and volatile metals can be obtained with a temperature-controlled transfer line acting as thermo-chromatograph. For less volatile metals the temperature of the target and ion source units needs to be kept as high as possible, but a selective ion source can be used: positive surface ionization for metals with ionization potentials below about 6 eV and the RILIS (resonance ionization laser ion source) technique for most other metals.

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