Cell-specific, spike timing–dependent plasticities in the dorsal cochlear nucleus

2004 ◽  
Vol 7 (7) ◽  
pp. 719-725 ◽  
Author(s):  
Thanos Tzounopoulos ◽  
Yuil Kim ◽  
Donata Oertel ◽  
Laurence O Trussell
Keyword(s):  
Cochlear Nucleus ◽  
Spike Timing ◽  
Dorsal Cochlear Nucleus

Model of auditory prediction in the dorsal cochlear nucleus via spike-timing dependent plasticity

2006 ◽  
Vol 69 (10-12) ◽  
pp. 1191-1194 ◽  
Author(s):  
Patrick D. Roberts ◽  
Christine V. Portfors ◽  
Nathaniel Sawtell ◽  
Richard Felix II
Keyword(s):  
Cochlear Nucleus ◽  
Spike Timing ◽  
Dorsal Cochlear Nucleus ◽  
Spike Timing Dependent Plasticity ◽  
Dependent Plasticity

scholarly journals Kv3 K+ currents contribute to spike-timing in dorsal cochlear nucleus principal cells

2018 ◽  
Vol 133 ◽  
pp. 319-333 ◽  
Author(s):  
Timothy Olsen ◽  
Alberto Capurro ◽  
Nadia Pilati ◽  
Charles H. Large ◽  
Martine Hamann
Keyword(s):  
Cochlear Nucleus ◽  
Spike Timing ◽  
Dorsal Cochlear Nucleus ◽  
Principal Cells ◽  
K Currents

scholarly journals Somatosensory inputs modify auditory spike timing in dorsal cochlear nucleus principal cells

2010 ◽  
Vol 33 (3) ◽  
pp. 409-420 ◽  
Author(s):  
Seth D. Koehler ◽  
Shashwati Pradhan ◽  
Paul B. Manis ◽  
Susan E. Shore
Keyword(s):  
Cochlear Nucleus ◽  
Spike Timing ◽  
Dorsal Cochlear Nucleus ◽  
Principal Cells

scholarly journals Action Potential Timing Precision in Dorsal Cochlear Nucleus Pyramidal Cells

2007 ◽  
Vol 97 (6) ◽  
pp. 4162-4172 ◽  
Author(s):  
Sarah E. Street ◽  
Paul B. Manis
Keyword(s):  
Firing Rate ◽  
Cochlear Nucleus ◽  
Pyramidal Neurons ◽  
Pyramidal Cells ◽  
Spike Trains ◽  
Spike Timing ◽  
Dorsal Cochlear Nucleus ◽  
Information Encoding ◽  
Temporal Precision ◽  
Noise Current

Many studies of the dorsal cochlear nucleus (DCN) have focused on the representation of acoustic stimuli in terms of average firing rate. However, recent studies have emphasized the role of spike timing in information encoding. We sought to ascertain whether DCN pyramidal cells might employ similar strategies and to what extent intrinsic excitability regulates spike timing. Gaussian distributed low-pass noise current was injected into pyramidal cells in a brain slice preparation. The shuffled autocorrelation-based analysis was used to compute a correlation index of spike times across trials. The noise causes the cells to fire with temporal precision (SD ≅ 1–2 ms) and high reproducibility. Increasing the coefficient of variation of the noise improved the reproducibility of the spike trains, whereas increasing the firing rate of the neuron decreased the neurons' ability to respond with predictable patterns of spikes. Simulated inhibitory postsynaptic potentials superimposed on the noise stimulus enhanced spike timing for >300 ms, although the enhancement was greatest during the first 100 ms. We also found that populations of pyramidal neurons respond to the same noise stimuli with correlated spike trains, suggesting that ensembles of neurons in the DCN receiving shared input can fire with similar timing. These results support the hypothesis that spike timing can be an important aspect of information coding in the DCN.

Blast-Induced tinnitus and spontaneous firing changes in the rat dorsal cochlear nucleus

2014 ◽  
Vol 92 (11) ◽  
pp. 1466-1477 ◽  
Author(s):  
Hao Luo ◽  
Edward Pace ◽  
Xueguo Zhang ◽  
Jinsheng Zhang
Keyword(s):  
Cochlear Nucleus ◽  
Dorsal Cochlear Nucleus ◽  
Spontaneous Firing
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