Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change

2013 ◽  
Vol 16 (5) ◽  
pp. 587-595 ◽  
Author(s):  
Iftach Dolev ◽  
Hilla Fogel ◽  
Hila Milshtein ◽  
Yevgeny Berdichevsky ◽  
Noa Lipstein ◽  
...  
Keyword(s):  
Conformational Change ◽  
Amyloid Β ◽  
Presenilin 1 ◽  
Spike Bursts

scholarly journals Monitoring amyloid-β 42 conformational change using a spray-printed graphene electrode

2021 ◽  
Vol 123 ◽  
pp. 106927
Author(s):  
Bing Li ◽  
Guohui Zhang ◽  
Islam Bogachan Tahirbegi ◽  
Michael J. Morten ◽  
Haijie Tan
Keyword(s):  
Conformational Change ◽  
Amyloid Β ◽  
Graphene Electrode

Hydrophobicity and Conformational Change as Mechanistic Determinants for Nonspecific Modulators of Amyloid β Self-Assembly

Biochemistry ◽  
2011 ◽  
Vol 51 (1) ◽  
pp. 126-137 ◽  
Author(s):  
Axel Abelein ◽  
Benedetta Bolognesi ◽  
Christopher M. Dobson ◽  
Astrid Gräslund ◽  
Christofer Lendel
Keyword(s):  
Conformational Change ◽  
Self Assembly ◽  
Amyloid Β

Alterations in presenilin 1 processing by amyloid-β peptide in the rat retina

2007 ◽  
Vol 181 (1) ◽  
pp. 69-77 ◽  
Author(s):  
Helena R. Watts ◽  
Valerie Vince ◽  
Desmond T. Walsh ◽  
Laura G. Bresciani ◽  
Stephen M. Gentleman ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Presenilin 1 ◽  
Amyloid Β Peptide ◽  
Rat Retina

scholarly journals Interrelationship between Changes in the Amyloid β 42/40 Ratio and Presenilin 1 Conformation

2016 ◽  
Vol 22 (1) ◽  
pp. 329-337 ◽  
Author(s):  
Katarzyna Marta Zoltowska ◽  
Masato Maesako ◽  
Oksana Berezovska
Keyword(s):  
Amyloid Β ◽  
Presenilin 1

scholarly journals The Large Hydrophilic Loop of Presenilin 1 Is Important for Regulating γ-Secretase Complex Assembly and Dictating the Amyloid β Peptide (Aβ) Profile without Affecting Notch Processing

2010 ◽  
Vol 285 (12) ◽  
pp. 8527-8536 ◽  
Author(s):  
Johanna Wanngren ◽  
Jenny Frånberg ◽  
Annelie I. Svensson ◽  
Hanna Laudon ◽  
Fredrik Olsson ◽  
...  
Keyword(s):  
Amyloid Β ◽  
Presenilin 1 ◽  
Amyloid Β Peptide ◽  
Complex Assembly ◽  
Hydrophilic Loop

scholarly journals The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for γ-Secretase Activity and Amyloid β-Protein Generation

2000 ◽  
Vol 275 (5) ◽  
pp. 3173-3178 ◽  
Author(s):  
W. Taylor Kimberly ◽  
Weiming Xia ◽  
Talat Rahmati ◽  
Michael S. Wolfe ◽  
Dennis J. Selkoe
Keyword(s):  
Amyloid Β ◽  
Presenilin 1 ◽  
Amyloid Β Protein ◽  
Β Protein ◽  
Secretase Activity

P4-369: Folic Acid Modulate Presenilin 1 Inhibits Amyloid β-Peptide Production in N2A-App Cells

2016 ◽  
Vol 12 ◽  
pp. P1178-P1178
Author(s):  
Wen Li ◽  
Huan Liu ◽  
Xumei Zhang ◽  
Guowei Huang
Keyword(s):  
Folic Acid ◽  
Amyloid Β ◽  
Presenilin 1 ◽  
Amyloid Β Peptide

Enhancement of amyloid β 42 secretion by 28 different presenilin 1 mutations of familial Alzheimer's disease

1999 ◽  
Vol 265 (1) ◽  
pp. 61-63 ◽  
Author(s):  
Ohoshi Murayama ◽  
Taisuke Tomita ◽  
Naomi Nihonmatsu ◽  
Miyuki Murayama ◽  
Xiaoyan Sun ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Β ◽  
Presenilin 1 ◽  
Familial Alzheimer’S Disease ◽  
Familial Alzheimer's Disease
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